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"Arya G. Varthi"

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"Arya G. Varthi"

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Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly
Neurospine. 2021;18(1):226-233.   Published online March 31, 2021
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Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly
Neurospine. 2021;18(1):226-233.   Published online March 31, 2021
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Objective
The objective of the current study was to perform a retrospective review of a national database to assess the safety of cement augmentation for vertebral compression fractures in geriatric populations in varying age categories.
Methods
The 2005–2016 National Surgical Quality Improvement Program databases were queried to identify patients undergoing kyphoplasty or vertebroplasty in the following age categories: 60–69, 70–79, 80–89, and 90+ years old. Demographic variables, comorbidity status, procedure type, provider specialty, inpatient/outpatient status, number of procedure levels, and periprocedure complications were compared between age categories using chi-square analysis. Multivariate logistic regressions controlling for patient and procedural variables were then performed to assess the relative periprocedure risks of adverse outcomes of patients in the different age categories relative to those who were 60–69 years old.
Results
For the 60–69, 70–79, 80–89, and 90+ years old cohorts, 486, 822, 937, and 215 patients were identified, respectively. After controlling for patient and procedural variables, 30-day any adverse events, serious adverse events, reoperation, readmission, and mortality were not different for the respective age categories. Cases in the 80- to 89-year-old cohort were at increased risk of minor adverse events compared to cases in the 60- to 69-year-old cohort.
Conclusion
As the population ages, cement augmentation is being considered as a treatment for vertebral compression fractures in increasingly older patients. These results suggest that even the very elderly may be appropriately considered for these procedures (level of evidence: 3).

Citations

Citations to this article as recorded by  Crossref logo
  • Surgical management of spinal metastases from primary lung carcinoma: demographics, clinical characteristics, and outcomes—A retrospective analysis
    Jun Li, Yuhan Zheng, Xiaohua Lv, Rong Zeng, Yating Zhao, Yucheng Xiang, Ke Zhan, Congcong Liu, Houqing Long, Ke Chen
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Advantages of TiRobot-assisted surgery in the treatment of osteoporotic thoracolumbar compression fractures: a meta-analysis based on multiple clinical indicators
    Yu Liu, Zidong Xia, Huiling Chen, Jian Wang, Mengtian Cao, Guohang Shen, Mingyuan Fan, Kaiyong Wang, Yang Chen, Yupei Dai
    Journal of Robotic Surgery.2025;[Epub]     CrossRef
  • Spinal augmentation for vertebral body fractures in the elderly population
    Alexander R. Evans, Taylor Niznik, Chao Li, Zachary A. Smith
    GeroScience.2025;[Epub]     CrossRef
  • The future of ambulatory surgery for geriatric patients
    Mary Ann Vann
    Best Practice & Research Clinical Anaesthesiology.2023; 37(3): 343.     CrossRef
  • What are the risk factors for a second osteoporotic vertebral compression fracture?
    Sang Hoon Hwang, Pyung Goo Cho, Kyoung-Tae Kim, Keung Nyun Kim, Sang Hyun Kim, Sung Hyun Noh
    The Spine Journal.2023; 23(11): 1586.     CrossRef
  • Beyond Pain Relief: An In-Depth Review of Vertebral Height Restoration After Balloon Kyphoplasty in Vertebral Compression Fractures
    Siddharth K Patel, Sohael Khan, Ventaktesh Dasari, Suvarn Gupta
    Cureus.2023;[Epub]     CrossRef
  • Risk of Revision After Vertebral Augmentation for Osteoporotic Vertebral Fracture: A Narrative Review
    Shinji Takahashi, Hiroyuki Inose, Koji Tamai, Masayoshi Iwamae, Hidetomi Terai, Hiroaki Nakamura
    Neurospine.2023; 20(3): 852.     CrossRef
  • The Effectiveness of Vertebral Height Restoration Based on the Vertebroplasty Procedure Used to Treat Osteoporotic Vertebral Fractures
    Kunio Yokoyama, Naokado Ikeda, Hidekazu Tanaka, Yutaka Ito, Akira Sugie, Makoto Yamada, Masahiko Wanibuchi, Masahiro Kawanishi
    Neurospine.2023; 20(4): 1159.     CrossRef
  • Treatment for Osteoporotic Vertebral Fracture - A Short Review of Orthosis and Percutaneous Vertebroplasty and Balloon Kyphoplasty
    Masahiro Kawanishi, Hidekazu Tanaka, Yutaka Ito, Makoto Yamada, Kunio Yokoyama, Akira Sugie, Naokado Ikeda
    Neurospine.2023; 20(4): 1124.     CrossRef
  • Commentary on “Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty”
    Sahir S. Jabbouri, Peter G. Whang
    Neurospine.2023; 20(4): 1140.     CrossRef
  • Difference in the Cobb Angle Between Standing and Supine Position as a Prognostic Factor After Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures
    In-Suk Bae, Byung Gwan Moon, Hee In Kang, Jae Hoon Kim, Cheolsu Jwa, Deok Ryeong Kim
    Neurospine.2022; 19(2): 357.     CrossRef
  • Kyphoplasty: why, when and how?
    Umile Giuseppe Longo, Rocco Papalia, Sergio De Salvatore, Valentina Piccioni, Vincenzo Denaro
    International Journal of Bone Fragility.2022; 2(1): 41.     CrossRef
  • 11,311 View
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  • 11 Web of Science
  • 12 Crossref

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Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
Neurospine. 2020;17(4):871-878.   Published online December 31, 2020
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Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
Neurospine. 2020;17(4):871-878.   Published online December 31, 2020
Close
Objective
To compare the perioperative morbidity of 2-level anterior cervical discectomy and fusion (ACDF) with that of 1-level anterior cervical corpectomy and fusion (ACCF) for the treatment of cervical degenerative conditions.
Methods
A retrospective study of the 2005–2016 National Surgical Quality Improvement Program database for patients undergoing 2-level ACDF and 1-level ACCF was performed. Patient data included: age, sex, body mass index (BMI), functional status, and American Society of Anesthesiologists (ASA) physical status (PS) classification. Hospital data included: operative time and length of hospital stay (LOS). Thirty-day outcome data included: any, serious, and minor adverse events, return to the operating room, readmission, and mortality. After propensity matching for age, sex, ASA PS classification, functional status, and BMI, multivariate logistic regression analysis was used to compare outcomes between the 2 propensity-matched subcohorts. Finally, multivariate logistic regression that additionally controlled for operative time was performed to compare the 2 propensity-matched subcohorts.
Results
A total of 17,497 cases were identified, with 90.20% undergoing 2-level ACDF and 9.80% undergoing 1-level ACCF. Patients undergoing 2-level ACDF were younger, more likely to be female, had higher functional status, and had shorter operative time and LOS (p < 0.001). After propensity score matching, cases undergoing 1-level ACCF had a statistically significant higher rate of serious adverse events (p = 0.005). This difference was no longer significant after controlling for operative time.
Conclusion
While there was noted to be additional morbidity in 1-level ACCF cases relative to 2-level ACDF cases, the lack of difference once controlling for the surgical time supports using the procedure that best accomplishes the surgical objectives.

Citations

Citations to this article as recorded by  Crossref logo
  • Association of frailty with healthcare resource utilization after open thoracic/thoracolumbar posterior spinal fusion for adult spinal deformity
    Aladine A. Elsamadicy, Andrew B. Koo, Josiah J. Z. Sherman, Margot Sarkozy, Benjamin C. Reeves, Samuel Craft, Sumaiya Sayeed, Mani Ratnesh S. Sandhu, Andrew M. Hersh, Sheng-Fu Larry Lo, John H. Shin, Ehud Mendel, Daniel M. Sciubba
    European Spine Journal.2026; 35(6): 3027.     CrossRef
  • A Meta-Analysis of Surgical Outcomes in 25727 Patients Undergoing Anterior Cervical Discectomy and Fusion or Anterior Cervical Corpectomy and Fusion for Cervical Deformity
    Karma Barot, Miguel A. Ruiz-Cardozo, Som Singh, Gabriel Trevino, Michael R. Kann, Samuel Brehm, Tim Bui, Karan Joseph, Rujvee Patel, Angela Hardi, Alexander T. Yahanda, Julio J. Jauregui, Magalie Cadieux, Brenton Pennicooke, Camilo A. Molina
    Global Spine Journal.2025; 15(2): 1390.     CrossRef
  • Association of malnutrition with surgical outcomes after spine surgery for spinal epidural abscess
    Aladine A. Elsamadicy, Paul Serrato, Shaila D. Ghanekar, Lucas P. Mitre, Syed I. Khalid, Sheng-fu Larry Lo, Daniel M. Sciubba
    Clinical Neurology and Neurosurgery.2025; 249: 108754.     CrossRef
  • Anterior Cervical Discectomy and Fusion vs. Anterior Cervical Corpectomy and Fusion for 2-Level Degenerative Cervical Myelopathy
    Aman Verma, Anil Kumar, Utsav Anand, Siddharth Sekhar Sethy, Aakash Jain, Vibhor Abrol, Kaustubh Ahuja, Bhaskar Sarkar, Pankaj Kandwal
    JBJS Reviews.2025;[Epub]     CrossRef
  • Comparison of Recent Efficacy of Two Surgical Techniques for Multi-Stage Radiculopathy Cervical Spondylosis
    斌 闫
    Advances in Clinical Medicine.2025; 15(04): 758.     CrossRef
  • Composite RAI, Malnutrition, and Anemia Model Superiorly Predicts 30-Day Morbidity and Mortality After Surgery for Adult Spinal Deformity
    Aladine A. Elsamadicy, Paul Serrato, Shaila D. Ghanekar, Justice Hansen, Ethan D. L. Brown, Syed I. Khalid, Daniel Schneider, Sheng-fu Larry Lo, Daniel M. Sciubba
    Journal of Clinical Medicine.2025; 14(15): 5379.     CrossRef
  • Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty
    Aladine A. Elsamadicy, Andrew B. Koo, Benjamin C. Reeves, James L. Cross, Andrew Hersh, Astrid C. Hengartner, Aditya V. Karhade, Zach Pennington, Oluwaseun O. Akinduro, Sheng-Fu Larry Lo, Ziya L. Gokaslan, John H. Shin, Ehud Mendel, Daniel M. Sciubba
    Global Spine Journal.2024; 14(4): 1227.     CrossRef
  • Association of Malnutrition with Surgical and Hospital Outcomes after Spine Surgery for Spinal Metastases: A National Surgical Quality Improvement Program Study of 1613 Patients
    Aladine A. Elsamadicy, John Havlik, Benjamin C. Reeves, Josiah J. Z. Sherman, Samuel Craft, Paul Serrato, Sumaiya Sayeed, Andrew B. Koo, Syed I. Khalid, Sheng-Fu Larry Lo, John H. Shin, Ehud Mendel, Daniel M. Sciubba
    Journal of Clinical Medicine.2024; 13(6): 1542.     CrossRef
  • A Comparison of Short-Term Outcomes after Surgical Treatment of Multilevel Degenerative Cervical Myelopathy in the Geriatric Patient Population: An Analysis of the National Surgical Quality Improvement Program Database 2010–2020
    Jeffrey Hyun-Kyu Choi, Paramveer Singh Birring, Joshua Lee, Sohaib Zafar Hashmi, Nitin Narain Bhatia, Yu-po Lee
    Asian Spine Journal.2024; 18(2): 190.     CrossRef
  • Does the novel artificial cervical joint complex resolve the conflict between stability and mobility after anterior cervical surgery? a finite element study
    Bing Meng, Xiong Zhao, Xin-Li Wang, Jian Wang, Chao Xu, Wei Lei
    Frontiers in Bioengineering and Biotechnology.2024;[Epub]     CrossRef
  • Safety of anterior cervical corpectomy and fusion (ACCF) for the treatment of subaxial cervical spine injuries, a single center comparative matched analysis
    Victor Gabriel El-Hajj, Aman Singh, Alexander Fletcher-Sandersjöö, Simon Blixt, Vasilios Stenimahitis, Gunnar Nilsson, Paul Gerdhem, Erik Edström, Adrian Elmi-Terander
    Acta Neurochirurgica.2024;[Epub]     CrossRef
  • Association of inpatient opioid consumption on postoperative outcomes after open posterior spinal fusion for adult spine deformity
    Aladine A. Elsamadicy, Mani Ratnesh S. Sandhu, Benjamin C. Reeves, Isaac G. Freedman, Andrew B. Koo, Christina Jayaraj, Astrid C. Hengartner, John Havlik, Andrew M. Hersh, Zach Pennington, Sheng-Fu Larry Lo, John H. Shin, Ehud Mendel, Daniel M. Sciubba
    Spine Deformity.2023; 11(2): 439.     CrossRef
  • Geriatric relationship with inpatient opioid consumption and hospital outcomes after open posterior spinal fusion for adult spine deformity
    Aladine A. Elsamadicy, Mani Ratnesh S. Sandhu, Benjamin C. Reeves, Josiah J.Z. Sherman, Samuel Craft, Mica Williams, John H. Shin, Daniel M. Sciubba
    Clinical Neurology and Neurosurgery.2023; 224: 107532.     CrossRef
  • Correction and Maintenance of Cervical Alignment
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    Clinical Spine Surgery.2023; 36(4): E118.     CrossRef
  • Comparison of anterior cervical discectomy and fusion versus anterior cervical corpectomy and fusion in the treatment of localized ossification of the posterior longitudinal ligament
    Tangyiheng Chen, Yujie Wang, Hong Zhou, Cheng Lin, Xuefeng Li, Huilin Yang, Yijie Liu, Weimin Jiang
    Journal of Orthopaedic Surgery.2023;[Epub]     CrossRef
  • MRI T2WI High Signal Is a Risk Factor for Perioperative Complications in Patients with Cervical Spondylosis with Spinal Cord Compression: A Propensity Matching Score Analysis
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    BioMed Research International.2022;[Epub]     CrossRef
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  • Marfan syndrome and adolescent idiopathic scoliosis patients have similar 90-day postoperative outcomes and 5-year reoperation rates after spinal deformity surgery
    Peter Y. Joo, Dennis L. Caruana, Michael J. Gouzoulis, Harold G. Moore, Justin R. Zhu, Bijan Ameri, Jonathan N. Grauer
    Spine Deformity.2022; 10(5): 1169.     CrossRef
  • Critical analysis of the evaluation of postoperative dysphagia following an anterior cervical discectomy and fusion
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    American Journal of Otolaryngology.2022; 43(3): 103466.     CrossRef
  • Anterior Cervical Corpectomy and Fusion for Degenerative Cervical Spondylotic Myelopathy
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    Clinical Spine Surgery.2022; 35(10): 440.     CrossRef
  • Biomechanics of a novel artificial cervical vertebra from an in vivo caprine cervical spine non-fusion model
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    Interdisciplinary Neurosurgery.2021; 25: 101206.     CrossRef
  • Effects of preoperative nutritional status on complications and readmissions after posterior lumbar decompression and fusion for spondylolisthesis: A propensity-score analysis
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  • 10,318 View
  • 127 Download
  • 23 Web of Science
  • 24 Crossref