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"Benjamin Khechen"

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Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion
Neurospine. 2019;16(4):772-779.   Published online July 8, 2019
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Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion
Neurospine. 2019;16(4):772-779.   Published online July 8, 2019
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Objective
The relationship between bone graft technique and postoperative outcomes for minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) has not been well-defined. This study aims to determine the effect of iliac crest bone grafting (ICBG) on patient-reported outcomes (PROs) and complication rates following MIS TLIF.
Methods
Primary, single-level MIS TLIF patients were consecutively analyzed. Patients that prospectively received a percutaneous technique of ICBG were compared to patients that retrospectively received bone morphogenetic protein-2 (BMP-2). Complication rates were assessed perioperatively and up to 1 year postoperatively. Changes in Oswestry Disability Index (ODI), visual analogue scale (VAS) back, and VAS leg pain were compared. Rates of minimum clinically important difference (MCID) achievement at final follow-up for ODI, VAS back, and VAS leg scores were compared.
Results
One hundred forty-nine patients were included: 101 in the BMP-2 cohort and 48 in the ICBG cohort. The ICBG cohort demonstrated increases in intraoperative blood loss and shorter lengths of stay. ICBG patients also experienced longer operative times, though this did not reach statistical significance. No significant differences in complication or reoperation rates were identified. The ICBG cohort demonstrated greater improvements in VAS leg pain at 6-week and 12-week follow-up. No other significant differences in PROs or MCID achievement rates were identified.
Conclusion
Patients undergoing MIS TLIF with ICBG experienced clinically insignificant increases in intraoperative blood loss and did not experience increases in postoperative pain or disability. Complication and reoperation rates were similar between groups. These results suggest that ICBG is a safe option for MIS TLIF.

Citations

Citations to this article as recorded by  Crossref logo
  • Posterior Wall Reconstruction Using Iliac Strut Graft in Posterior Acetabular Wall Fracture
    SINA HAGHIGHAT, MAZIAR MALEKZADE, ALI MOUSAPOUR, YAHYA SALIMI, VAHID FEIZOLAHI, GHOBAD RAMEZANI
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca.2026; 92(6): 343.     CrossRef
  • Analysis of Procedural Costs and Outcomes Between Autograft, BMP-2, and Viable Cellular Allograft in Lumbar Interbody Fusions
    Thomas P. Giannasca, Michael Mancini, Jake M. Laverdiere, Ekrem M. Ayhan, Marissa Gedman, Alexander K. Hahn, Laura Sanzari, Aris Yannopoulos
    Spine.2026; 51(7): 508.     CrossRef
  • A systematic review of bone graft products used in lumbar interbody fusion procedures for degenerative disc disease
    Anita Fitzgerald, Rachael McCool, Emma Carr, Paul Miller, Katie Reddish, Cynthia C Lohr, Elena Annoni, Brandon Lawrence
    North American Spine Society Journal (NASSJ).2025; 21: 100579.     CrossRef
  • Evolution of the Minimally Invasive Surgery Transforaminal Lumbar Interbody Fusion: Where Are We Now?
    Abraham Dada, Satvir Saggi, Vardhaan S. Ambati, Arati Patel, Praveen V. Mummaneni
    Neurosurgery.2025; 96(3S): S33.     CrossRef
  • Efficacy and Safety of Osteobiologics for Lumbar Spinal Fusion
    Luca Ambrosio, Jordy Schol, Shota Tamagawa, Sathish Muthu, Daisuke Sakai, Rocco Papalia, Gianluca Vadalà, Vincenzo Denaro
    Journal of Bone and Joint Surgery.2025; 107(18): 2110.     CrossRef
  • Comparative Efficacy of Bone Graft Materials in Transforaminal Lumbar Interbody Fusion: A Systematic Review and Meta-Analysis
    Sami Al Eissa, Fahad Al Helal, Majed Abaalkhail, Abdullah Al Shehri, Raed Al Mousa, Abdullah Bin Shabib, Hussam Al Angari, Abdulrahman M. AlJahani, Dana W. AlDughiman
    Journal of Spine Practice.2025; 4(3): 88.     CrossRef
  • Comparative evaluation of clinical-radiological outcomes of Russian osteoplastic material BioOst in minimally invasive transforaminal interbody fusion
    V. V. Khlebov, I. V. Volkov
    Russian Neurosurgical Journal named after Professor A. L. Polenov.2025; 17(3): 123.     CrossRef
  • Comparative Analysis of ABM/P-15, Bone Morphogenic Protein and Demineralized Bone Matrix after Instrumented Lumbar Interbody Fusion
    Ashwin Sathe, Sang-Ho Lee, Shin-Jae Kim, Sang Soo Eun, Yong Soo Choi, Shih-min Lee, Ju-Wan Seuk, Yoon Sun Lee, Sang-Ha Shin, Junseok Bae
    Journal of Korean Neurosurgical Society.2022; 65(6): 825.     CrossRef
  • A BMP/Activin A Chimera Induces Posterolateral Spine Fusion in Nonhuman Primates at Lower Concentrations Than BMP-2
    Howard J. Seeherman, Christopher G. Wilson, Eric J. Vanderploeg, Christopher T. Brown, Pablo R. Morales, Douglas C. Fredricks, John M. Wozney
    Journal of Bone and Joint Surgery.2021; 103(16): e64.     CrossRef
  • A Prospective, Multi-Center, Double-Blind, Randomized Study to Evaluate the Efficacy and Safety of the Synthetic Bone Graft Material DBM Gel with rhBMP-2 versus DBM Gel Used during the TLIF Procedure in Patients with Lumbar Disc Disease
    Seung-Jae Hyun, Seung Hwan Yoon, Joo Han Kim, Jae Keun Oh, Chang-Hyun Lee, Jun Jae Shin, Jiin Kang, Yoon Ha
    Journal of Korean Neurosurgical Society.2021; 64(4): 562.     CrossRef
  • Autologous Bone Grafting in Trauma and Orthopaedic Surgery: An Evidence-Based Narrative Review
    Filippo Migliorini, Francesco Cuozzo, Ernesto Torsiello, Filippo Spiezia, Francesco Oliva, Nicola Maffulli
    Journal of Clinical Medicine.2021; 10(19): 4347.     CrossRef
  • Minimally invasive transforaminal lumbar interbody fusion — A narrative review on the present status
    S. Phani Kiran, G. Sudhir
    Journal of Clinical Orthopaedics and Trauma.2021; 22: 101592.     CrossRef
  • Efficacy for Whitlockite for Augmenting Spinal Fusion
    Su Yeon Kwon, Jung Hee Shim, Yu Ha Kim, Chang Su Lim, Seong Bae An, Inbo Han
    International Journal of Molecular Sciences.2021; 22(23): 12875.     CrossRef
  • 12,360 View
  • 250 Download
  • 11 Web of Science
  • 13 Crossref

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Swallowing Function Following Anterior Cervical Discectomy and Fusion With and Without Anterior Plating: A SWAL-QOL (Swallowing-Quality of Life) and Radiographic Assessment
Neurospine. 2019;16(3):601-607.   Published online July 8, 2019
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Swallowing Function Following Anterior Cervical Discectomy and Fusion With and Without Anterior Plating: A SWAL-QOL (Swallowing-Quality of Life) and Radiographic Assessment
Neurospine. 2019;16(3):601-607.   Published online July 8, 2019
Close
Objective
Anterior cervical plating in anterior cervical discectomy and fusion (ACDF) procedures are associated with improved outcomes compared to stand-alone cages. However, concerns exist regarding increased rates of postoperative dysphagia following an ACDF. This study aims to quantify the effect of anterior plating on swallowing-quality of life (SWAL-QOL) scores and radiographic swelling assessments following a primary, single-level ACDF.
Methods
Patients retrospectively reviewed. Patients grouped into those receiving a cage or anterior plate. SWAL-QOL scores were recorded preoperatively and 6 weeks and 12 weeks postoperatively. Lateral radiographs were used to create a swelling index with a ratio of the prevertebral swelling distance to the anterior-posterior diameter of each involved vertebral body. An air index was created using the same methodology. Statistical analysis was performed using chi-square analysis and independent t-tests for categorical and continuous variables.
Results
Sixty-eight primary, single-level ACDF patients were included. Forty-one (60.3%) received a stand-alone cage and 27 (39.7%) received a cage with anterior plating. No differences in demographics, comorbidities, operative time, estimated blood loss, or length of hospital stay were identified between Cage and Plate cohorts. Finally, no differences were observed in postoperative SWAL-QOL scores or swelling and air indices between groups.
Conclusion
The results demonstrate that patients undergoing a primary, single-level ACDF with or without anterior plating experience similar operative times and lengths of stay. Patients that receive a cage with anterior plating did not experience significant increases in dysphagia as measured by the SWAL-QOL questionnaire compared to patients that received a stand-alone cage. Furthermore, radiographic assessments of swelling are comparable.

Citations

Citations to this article as recorded by  Crossref logo
  • Can we predict postoperative dysphagia after anterior cervical discectomy and fusion based on lateral x-ray? An external validation of two outcome scores
    Gloria Cabrera, Andrés Rojas-Gil, Nuria Montagut, Jorge Herrero Hernando, Jorge Torales, Alberto Di Somma, Abel Ferrés, Pedro Roldán, Ramon Torné, Alejandra Mosteiro, Jose Poblete Carizo
    Neurosurgical Review.2026;[Epub]     CrossRef
  • Evolving trends in anterior cervical spine surgery: a decade-long shift towards standalone constructs
    Nolan M. Reinhart, Jackson P. Tate, Zachary Salas, William F. Sherman, Mathew Cyriac
    Current Orthopaedic Practice.2026;[Epub]     CrossRef
  • Comparison of Interbody Fusion Strategies in Anterior Cervical Discectomy and Fusion: A Network Meta-Analysis and Systematic Review
    Hongfeng Meng, Tianyu Jin, Jialu Wang, Xiangtian Ji, Zhiyuan Peng, Maoyang Qi, Can Zhang, Wanru Duan, Zan Chen
    World Neurosurgery.2024; 190: 65.     CrossRef
  • Using Swallowing Quality of Life to Compare Oropharyngeal Dysphagia Following Cervical Disc Arthroplasty or Anterior Cervical Discectomy and Fusion
    Shruthi Mohan, Caroline N Jadczak, Elliot D K Cha, Conor P Lynch, Madhav R Patel, Kevin C Jacob, Hanna Pawlowski, Michael C Prabhu, Nisheka N Vanjani, Kern Singh
    Journal of Minimally Invasive Spine Surgery and Technique.2022; 7(1): 140.     CrossRef
  • Surgical Treatment of Dysphagia Secondary to Anterior Cervical Osteophytes Due to Diffuse Idiopathic Skeletal Hyperostosis
    Ho Yong Choi, Dae Jean Jo
    Medicina.2022; 58(7): 928.     CrossRef
  • Comparison of the effectiveness and safety of bioactive glass ceramic to allograft bone for anterior cervical discectomy and fusion with anterior plate fixation
    Hyung Cheol Kim, Jae Keun Oh, Du Su Kim, Jeffrey S. Roh, Tae Woo Kim, Seong Bae An, Hyeong Seok Jeon, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Do Heum Yoon, Yoon Ha
    Neurosurgical Review.2020; 43(5): 1423.     CrossRef
  • Surgical Outcomes of Dysphagia Provoked by Diffuse Idiopathic Skeletal Hyperostosis in the Cervical Spine
    Young Soo Chung, Ho Yeol Zhang, Yoon Ha, Jeong-Yoon Park
    Yonsei Medical Journal.2020; 61(4): 341.     CrossRef
  • Biomechanical Comparison of a New Memory Compression Alloy Plate versus Traditional Titanium Plate for Anterior Cervical Discectomy and Fusion: A Finite Element Analysis
    Jiantao Liu, Runqing Wang, Hongbo Wang, Yanbiao Wang, Dongbo Lv, Pan Diao, Shihan Feng, Yanzheng Gao, Aijun Wang
    BioMed Research International.2020;[Epub]     CrossRef
  • Minimum Clinically Important Differences of the Hospital for Special Surgery Dysphagia and Dysphonia Inventory and Other Dysphagia Measurements in Patients Undergoing ACDF
    Ichiro Okano, Courtney Ortiz Miller, Stephan N. Salzmann, Yushi Hoshino, Jennifer Shue, Andrew A. Sama, Frank P. Cammisa, Federico P. Girardi, Alexander P. Hughes
    Clinical Orthopaedics & Related Research.2020; 478(10): 2309.     CrossRef
  • 10,726 View
  • 264 Download
  • 11 Web of Science
  • 9 Crossref

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Postoperative Fever Evaluation Following Lumbar Fusion Procedures
Neurospine. 2018;15(2):154-162.   Published online June 19, 2018
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Postoperative Fever Evaluation Following Lumbar Fusion Procedures
Neurospine. 2018;15(2):154-162.   Published online June 19, 2018
Close
Objective
This study aimed to determine the incidence of postoperative fever, the workup conducted for postoperative fever, the rate of subsequent fever-related diagnoses or complications, and the risk factors associated with fever following lumbar fusion.
Methods
A retrospective review of patients undergoing lumbar fusion was performed. For patients in whom fever (≥38.6°C) was documented, charts were reviewed for any fever workup or diagnosis. Multivariate regression was used to identify independent risk factors for the development of postoperative fever.
Results
A total of 868 patients met the inclusion criteria, of whom 105 exhibited at least 1 episode of fever during hospitalization. The first documentation of fever occurred during the first 24 hours in 43.8% of cases, during postoperative hours 24–48 in 53.3%, and later than 48 hours postoperatively in 2.9%. At least 1 component of a fever workup was conducted in 47 of the 105 patients who had fever, resulting in fever-associated diagnoses in 4 patients prior to discharge. Three patients who had fever during the inpatient stay developed complications after discharge. On multivariate analysis, operations longer than 150 minutes (relative risk [RR], 1.66; p=0.015) and narcotic consumption greater than 85 oral morphine equivalents on postoperative day 0 (RR, 1.53; p=0.038) were independently associated with an increased risk of developing postoperative fever.
Conclusion
The results of this study suggest that inpatient fever occurred in roughly 1 in 8 patients following lumbar fusion surgery. In most cases where a fever workup was performed, no cause of fever was detected. Longer operative time and increased early postoperative narcotic use may increase the risk of developing postoperative fever.

Citations

Citations to this article as recorded by  Crossref logo
  • Postoperative Fever in Children Hospitalized After Surgery: Incidence and Risk Factors
    Peter J. Hong, Lynne Ferrari, Steven Staffa, Ben Reis, Maria Osipovich, Jonathan D. Hron, Jay G. Berry
    Hospital Pediatrics.2026; 16(5): 357.     CrossRef
  • Postoperative fever after elective minimally invasive resection for gastric and colorectal cancer: incidence, risk factors and characteristics
    Fan He, Chenglin Tang, Fuyu Yang, Dongqin Zhao, Junjie Xiong, Yu Zou, Defei Chen, Guoquan Huang, Kun Qian
    Frontiers in Oncology.2025;[Epub]     CrossRef
  • Postoperative Fever Following Pelvic and Acetabular Fixation: Incidence, Risk Factors, and Lack of Association With Surgical Site Infection
    Mark Ayoub, Eric Curtis, Yeng Vue, Daniel Wilson, Kamran Movassaghi
    Orthopedics.2025; 48(4): 229.     CrossRef
  • Postoperative Noninfectious Fever in Degenerative Lumbar Spine Diseases: A Multivariate Logistic Regression Analysis
    Yao Li, Guanyu Yang, Tianci Fang, Fanqi Kong, Peng Yang, Bin Pi, Huilin Yang, Xuwei Ling
    World Neurosurgery.2025; 200: 124190.     CrossRef
  • A Randomized Study on the Prophylactic Use of Acetaminophen to Prevent Fever after the Removal of Drainage Tubes for Lumbar Surgery
    Kaifeng Ye, Yan Li, Yong Xing, Kaixi Liu, Fang Zhou, Yun Tian, Yanping Zhang
    Orthopaedic Surgery.2023; 15(2): 440.     CrossRef
  • Preoperative predictors of prolonged hospitalization in patients undergoing lateral lumbar interbody fusion
    James W. Nie, Timothy J. Hartman, Keith R. MacGregor, Omolabake O. Oyetayo, Eileen Zheng, Vincent P. Federico, Dustin H. Massel, Arash J. Sayari, Kern Singh
    Acta Neurochirurgica.2023; 165(9): 2615.     CrossRef
  • Single-Level Minimally Invasive Transforaminal Lumbar Interbody Fusion versus Anterior Lumbar Interbody Fusion with Posterior Instrumentation at L5/S1
    Kevin C. Jacob, Madhav R. Patel, Max A. Ribot, Alexander W. Parsons, Nisheka N. Vanjani, Hanna Pawlowski, Michael C. Prabhu, Kern Singh
    World Neurosurgery.2022; 157: e111.     CrossRef
  • Postoperative fever after liver resection: Incidence, risk factors, and characteristics associated with febrile infectious complication
    Hon-Fan Lai, Ivy Yenwen Chau, Hao-Jan Lei, Shu-Cheng Chou, Cheng-Yuan Hsia, Yi-Chu Kao, Gar-Yang Chau, Leonidas G Koniaris
    PLOS ONE.2022; 17(1): e0262113.     CrossRef
  • Preoperative Cognitive Impairment as a Predictor of Postoperative Outcomes in Elderly Patients Undergoing Spinal Surgery for Degenerative Spinal Disease
    Hyung Cheol Kim, Seong Bae An, Hyeongseok Jeon, Tae Woo Kim, Jae Keun Oh, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Phil Hyu Lee, Suk Yun Kang, Yoon Ha
    Journal of Clinical Medicine.2021; 10(7): 1385.     CrossRef
  • Association Between Postoperative Fever and Readmission Rates in Lumbar Fusion Patients
    Geoffrey P. Stricsek, Thiago S. Montenegro, Glenn A. Gonzalez, Akash Singh, Catriona Harrop, James Harrop
    Clinical Spine Surgery.2021; 34(6): E349.     CrossRef
  • Local temperature elevation as a marker of spinal implant infection in an animal model
    Steven D. Glassman, Leah Y. Carreon, Olumide Aruwajoye, Nicholas M. Benson, Ping Li, Arjun Siby Kurian
    North American Spine Society Journal (NASSJ).2021; 7: 100077.     CrossRef
  • The Effect of the Severity of Preoperative Back Pain on Patient-Reported Outcomes, Recovery Ratios, and Patient Satisfaction Following Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS-TLIF)
    Kevin C. Jacob, Madhav R. Patel, Alexander W. Parsons, Nisheka N. Vanjani, Hanna Pawlowski, Michael C. Prabhu, Kern Singh
    World Neurosurgery.2021; 156: e254.     CrossRef
  • Experimental Comparison of Autograft and DBM Flex (Grafton) for Spinal Lumbar Fusion in Rabbits
    Cem DEMİREL, Dursun TÜRKÖZ, Tuncay YİLMAZ
    Archives of Clinical and Experimental Medicine.2021; 6(3): 153.     CrossRef
  • Comparison of Fusion Rate between Demineralized Bone Matrix versus Autograft in Lumbar Fusion : Meta-Analysis
    Sanghyun Han, Bumsoo Park, Jeong-Wook Lim, Jin-Young Youm, Seoung-Won Choi, Dae Hwan Kim, Dong Ki Ahn
    Journal of Korean Neurosurgical Society.2020; 63(6): 673.     CrossRef
  • Management of Common Postoperative Complications
    Christopher Stephenson, Arya Mohabbat, David Raslau, Elizabeth Gilman, Elizabeth Wight, Deanne Kashiwagi
    Mayo Clinic Proceedings.2020; 95(11): 2540.     CrossRef
  • 15,576 View
  • 188 Download
  • 13 Web of Science
  • 15 Crossref