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"Comron Saifi"

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Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly
Neurospine. 2021;18(1):226-233.   Published online March 31, 2021
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Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly
Neurospine. 2021;18(1):226-233.   Published online March 31, 2021
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Objective
The objective of the current study was to perform a retrospective review of a national database to assess the safety of cement augmentation for vertebral compression fractures in geriatric populations in varying age categories.
Methods
The 2005–2016 National Surgical Quality Improvement Program databases were queried to identify patients undergoing kyphoplasty or vertebroplasty in the following age categories: 60–69, 70–79, 80–89, and 90+ years old. Demographic variables, comorbidity status, procedure type, provider specialty, inpatient/outpatient status, number of procedure levels, and periprocedure complications were compared between age categories using chi-square analysis. Multivariate logistic regressions controlling for patient and procedural variables were then performed to assess the relative periprocedure risks of adverse outcomes of patients in the different age categories relative to those who were 60–69 years old.
Results
For the 60–69, 70–79, 80–89, and 90+ years old cohorts, 486, 822, 937, and 215 patients were identified, respectively. After controlling for patient and procedural variables, 30-day any adverse events, serious adverse events, reoperation, readmission, and mortality were not different for the respective age categories. Cases in the 80- to 89-year-old cohort were at increased risk of minor adverse events compared to cases in the 60- to 69-year-old cohort.
Conclusion
As the population ages, cement augmentation is being considered as a treatment for vertebral compression fractures in increasingly older patients. These results suggest that even the very elderly may be appropriately considered for these procedures (level of evidence: 3).

Citations

Citations to this article as recorded by  Crossref logo
  • Surgical management of spinal metastases from primary lung carcinoma: demographics, clinical characteristics, and outcomes—A retrospective analysis
    Jun Li, Yuhan Zheng, Xiaohua Lv, Rong Zeng, Yating Zhao, Yucheng Xiang, Ke Zhan, Congcong Liu, Houqing Long, Ke Chen
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Advantages of TiRobot-assisted surgery in the treatment of osteoporotic thoracolumbar compression fractures: a meta-analysis based on multiple clinical indicators
    Yu Liu, Zidong Xia, Huiling Chen, Jian Wang, Mengtian Cao, Guohang Shen, Mingyuan Fan, Kaiyong Wang, Yang Chen, Yupei Dai
    Journal of Robotic Surgery.2025;[Epub]     CrossRef
  • Spinal augmentation for vertebral body fractures in the elderly population
    Alexander R. Evans, Taylor Niznik, Chao Li, Zachary A. Smith
    GeroScience.2025;[Epub]     CrossRef
  • The future of ambulatory surgery for geriatric patients
    Mary Ann Vann
    Best Practice & Research Clinical Anaesthesiology.2023; 37(3): 343.     CrossRef
  • What are the risk factors for a second osteoporotic vertebral compression fracture?
    Sang Hoon Hwang, Pyung Goo Cho, Kyoung-Tae Kim, Keung Nyun Kim, Sang Hyun Kim, Sung Hyun Noh
    The Spine Journal.2023; 23(11): 1586.     CrossRef
  • Beyond Pain Relief: An In-Depth Review of Vertebral Height Restoration After Balloon Kyphoplasty in Vertebral Compression Fractures
    Siddharth K Patel, Sohael Khan, Ventaktesh Dasari, Suvarn Gupta
    Cureus.2023;[Epub]     CrossRef
  • Risk of Revision After Vertebral Augmentation for Osteoporotic Vertebral Fracture: A Narrative Review
    Shinji Takahashi, Hiroyuki Inose, Koji Tamai, Masayoshi Iwamae, Hidetomi Terai, Hiroaki Nakamura
    Neurospine.2023; 20(3): 852.     CrossRef
  • The Effectiveness of Vertebral Height Restoration Based on the Vertebroplasty Procedure Used to Treat Osteoporotic Vertebral Fractures
    Kunio Yokoyama, Naokado Ikeda, Hidekazu Tanaka, Yutaka Ito, Akira Sugie, Makoto Yamada, Masahiko Wanibuchi, Masahiro Kawanishi
    Neurospine.2023; 20(4): 1159.     CrossRef
  • Treatment for Osteoporotic Vertebral Fracture - A Short Review of Orthosis and Percutaneous Vertebroplasty and Balloon Kyphoplasty
    Masahiro Kawanishi, Hidekazu Tanaka, Yutaka Ito, Makoto Yamada, Kunio Yokoyama, Akira Sugie, Naokado Ikeda
    Neurospine.2023; 20(4): 1124.     CrossRef
  • Commentary on “Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty”
    Sahir S. Jabbouri, Peter G. Whang
    Neurospine.2023; 20(4): 1140.     CrossRef
  • Difference in the Cobb Angle Between Standing and Supine Position as a Prognostic Factor After Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures
    In-Suk Bae, Byung Gwan Moon, Hee In Kang, Jae Hoon Kim, Cheolsu Jwa, Deok Ryeong Kim
    Neurospine.2022; 19(2): 357.     CrossRef
  • Kyphoplasty: why, when and how?
    Umile Giuseppe Longo, Rocco Papalia, Sergio De Salvatore, Valentina Piccioni, Vincenzo Denaro
    International Journal of Bone Fragility.2022; 2(1): 41.     CrossRef
  • 11,311 View
  • 222 Download
  • 11 Web of Science
  • 12 Crossref

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Rigid-Plating and Cortico-Cancellous Allograft Are Effective for 3-Level Anterior Cervical Discectomy and Fusion: Radiographic and Clinical Outcomes
Neurospine. 2020;17(1):146-155.   Published online April 12, 2019
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Rigid-Plating and Cortico-Cancellous Allograft Are Effective for 3-Level Anterior Cervical Discectomy and Fusion: Radiographic and Clinical Outcomes
Neurospine. 2020;17(1):146-155.   Published online April 12, 2019
Close
Objective
To determine the risk factors associated with radiographic changes and clinical outcomes following 3-level anterior cervical discectomy and fusion (ACDF) using rigidplate constructs and cortico-cancellous allograft. ACDF has demonstrated efficacy for treatment of multilevel degenerative cervical conditions, but current data exists in small heterogeneous forms.
Methods
A retrospective review included 98 patients with primary 3-level ACDF surgery at one institution from 2008 to 2013 with minimum 1-year follow-up. Cervical sagittal vertical axis (SVA), segmental height, fusion, and lordosis radiographs were measured preoperatively and at 2 postoperative periods.
Results
Rates of asymptomatic pseudarthroses and total reoperations were 18% and 4%, respectively. Results demonstrated immediate improvements in cervical lordosis (5.5°, p < 0.01) and segmental height (5.0-mm increase, p < 0.01) with little changes in the cervical SVA (3.2-mm increase, p < 0.01). The segmental height decreased from immediate postoperative period to final follow-up (1.7-mm decrease, p < 0.01). Older age was protective against radiolucent lines (p < 0.05). Patient-reported outcomes significantly improved following surgery (p < 0.01). Current smoking status and diagnosis of diabetes mellitus had no impact on radiographic or clinical outcomes. Risk factors were not identified for the 5 reoperations (4%).
Conclusion
Three-level ACDF with rigid-plating and cortico-cancellous allograft is an effective procedure for degenerative diseases of the cervical spine without the application of additional adjuncts or combined anteriorposterior cervical surgeries. Significant improvements in cervical lordosis, segmental height, and segmental alignment can be achieved with little change in cervical SVA and a low rate of reoperations over short-term follow-up. Similarly, patient-reported outcomes show significant improvements.

Citations

Citations to this article as recorded by  Crossref logo
  • Bone Density Distribution in the Cervical Spine
    Francis Lovecchio, Bryan Ang, Philip K. Louie, Chirag Chaudary, Sachin P. Shah, Ananth Punyala, Yu-Cheng Yao, Mike Steinhaus, Michael H. McCarthy, Russel Huang, Darren Lebl, Virginie Lafage, Todd J. Albert, Sravisht Iyer, Sheeraz Qureshi, Han Jo Kim
    Global Spine Journal.2024; 14(1): 169.     CrossRef
  • Anterior Plate-Screws and Lower Postoperative T1 Slope Affect Cervical Allospacer Failures in Multi-Level ACDF Surgery: Anterior Versus Posterior Fixation
    Kyung-Soo Suk, Kathryn Anne Jimenez, Je Hyung Jo, Hak-Sun Kim, Hwan-Mo Lee, Seong-Hwan Moon, Byung Ho Lee
    Global Spine Journal.2023; 13(1): 89.     CrossRef
  • Is 3D-printed Titanium cage a reliable option for 3-level anterior cervical discectomy and fusion in treating degenerative cervical spondylosis?
    Shanxi Wang, Xuan Fang, Yunkun Qu, Rui Lu, Xiaojun Yu, Shaoze Jing, Qing Ding, Chaoxu Liu, Hua Wu, Yang Liu
    Frontiers in Surgery.2023;[Epub]     CrossRef
  • Outcomes of 2-Level Versus 3- or 4-Level Anterior Cervical Discectomy and Fusion Using a Biomimetic Surface Titanium Cage: Multicenter Experience
    Alexander O. Aguirre, Mohamed A.R. Soliman, Nicholas J. Minissale, Patrick K. Jowdy, Cathleen C. Kuo, Asham Khan, Ryan M. Hess, David E. Smolar, Barrett I. Woods, Mark S. Eskander, Paul J. Slosar, John Pollina, Jeffrey P. Mullin
    World Neurosurgery.2023; 177: e453.     CrossRef
  • Mechanistically Scoping Cell‐Free and Cell‐Dependent Artificial Scaffolds in Rebuilding Skeletal and Dental Hard Tissues
    Peng Yu, Fanyuan Yu, Jie Xiang, Kai Zhou, Ling Zhou, Zhengmin Zhang, Xiao Rong, Zichuan Ding, Jiayi Wu, Wudi Li, Zongke Zhou, Ling Ye, Wei Yang
    Advanced Materials.2022;[Epub]     CrossRef
  • What Type of Incision for Anterior Cervical Spine Surgery Involving Long Segments Can Bring Better Cosmetic and Functional Outcomes?
    Hyung Rae Lee, Dong-Ho Lee, Sang Yun Seok, Sehan Park, Jae Hwan Cho, Chang Ju Hwang, Choon Sung Lee
    Neurospine.2022; 19(2): 412.     CrossRef
  • Morphologic Change of CorticoCancellous Allograft Used for Anterior Cervical Discectomy and Fusion
    Jae Jun Yang, Byungyoung Ryu, Ji Weon Moon, Taehyun Kim, Sehan Park
    Spine.2022; 47(13): 944.     CrossRef
  • The Effect of Subsidence on Segmental and Global Lordosis at Long-term Follow-up After Anterior Cervical Discectomy and Fusion
    Akiro H. Duey, Christopher Gonzalez, Eric A. Geng, Pierce J. Ferriter Jr, Ashley M. Rosenberg, Ula N. Isleem, Bashar Zaidat, Paul M. Al-Attar, Jonathan S. Markowitz, Jun S. Kim, Samuel K. Cho
    Neurospine.2022; 19(4): 927.     CrossRef
  • 8,239 View
  • 179 Download
  • 7 Web of Science
  • 8 Crossref