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"Eric O. Klineberg"

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"Eric O. Klineberg"

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Outcomes of Surgical Treatment for Patients With Mild Scoliosis and Age-Appropriate Sagittal Alignment With Minimum 2-Year Follow-up
Neurospine. 2023;20(3):837-848.   Published online September 30, 2023
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Outcomes of Surgical Treatment for Patients With Mild Scoliosis and Age-Appropriate Sagittal Alignment With Minimum 2-Year Follow-up
Neurospine. 2023;20(3):837-848.   Published online September 30, 2023
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Objective
The goal of this study was to determine if patients with mild scoliosis and age-appropriate sagittal alignment have favorable outcomes following surgical correction.
Methods
Retrospective review of a prospective, multicenter adult spinal deformity database. Inclusion criteria: operative patients age ≥18 years, and preoperative pelvic tilt, mismatch between pelvic incidence and lumbar lordosis (PI–LL), and C7 sagittal vertical axis all within established age-adjusted thresholds with minimum 2-year follow-up. Health-related quality of life (HRQoL) scores: Oswestry Disability Index (ODI), 36-item Short Form health survey (SF-36), Scoliosis Research Society-22R (SRS22R), back/leg pain Numerical Rating Scale and minimum clinically important difference (MCID)/substantial clinical benefit (SCB). Two-year and preoperative HRQoL radiographic data were compared. Patients with mild scoliosis (Mild Scoli, Max coronal Cobb 10°–30°) were compared to those with larger curves (Scoli).
Results
One hundred fifty-one patients included from 667 operative patients (82.8% women; average age, 56.4 ± 16.2 years). Forty-two patients (27.8%) included in Mild Scoli group. Mild Scoli group had significantly worse baseline leg pain, ODI, and physical composite scores (p < 0.02). Mean 2-year maximum coronal Cobb angle was significantly improved compared to baseline (p < 0.001). All 2-year HRQoL measures were significantly improved compared to (p < 0.001) except mental composite score, SRS activity and SRS mental for the Mild Scoli group (p > 0.05). From the mild Scoli group, 36%–74% met either MCID or SCB for the HRQoL measures. Sixty-four point three percent had minimum 1 complication, 28.6% had a major complication, 35.7% had reoperation.
Conclusion
Mild scoliosis patients with age-appropriate sagittal alignment benefit from surgical correction, decompression, and stabilization at 2 years postoperative despite having a high complication rate.

Citations

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  • Subject‐Specific Musculoskeletal Modeling: The Future of Predicting and Preventing Proximal Junctional Failure in Adult Spinal Deformity
    Nima Ashjaee, Alexa Semonche, Anthony L. Mikula, Laszlo Kiss, Dennis E. Anderson, Dominika Ignasiak, Stephen H. M. Brown, John Street, Sidney Fels, Samuel R. Ward, Christopher Ames, Thomas R. Oxland
    JOR SPINE.2025;[Epub]     CrossRef
  • 5,508 View
  • 158 Download
  • 3 Web of Science
  • 1 Crossref

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Ligament Augmentation With Mersilene Tape Reduces the Rates of Proximal Junctional Kyphosis and Failure in Adult Spinal Deformity
Neurospine. 2021;18(3):580-586.   Published online September 30, 2021
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Ligament Augmentation With Mersilene Tape Reduces the Rates of Proximal Junctional Kyphosis and Failure in Adult Spinal Deformity
Neurospine. 2021;18(3):580-586.   Published online September 30, 2021
Close
Objective
To investigate prevention of proximal junctional kyphosis (PJK) and failure (PJF) following adult spinal deformity (ASD) surgery utilizing a novel technique of posterior ligament augmentation with polyester fiber tether.
Methods
This study evaluated ASD adult patients who underwent posterior decompression and instrumented fusion from the thoracolumbar junction (T9–L1) to the pelvis from 2011–2017. Basic demographic data were obtained. Radiographic outcomes included proximal junctional angle (PJA), sagittal vertical axis, PJK, and PJF. The study population was divided into patients who had ASD surgery with and without ligamentous augmentation.
Results
A total of 43 subjects were evaluated, including 20 without and 23 with ligamentous augmentation. PJA increased over time for both groups. PJA was smaller for the augmented group, and rate of increase in PJA was slower in the augmented group (p < 0.0001). The rate of PJK was significantly higher in the nonaugmented group (p = 0.01). PJF was significantly less common in the augmented group (p = 0.003). Time to revision surgery was lower in the nonaugmented group (p = 0.003).
Conclusion
Our novel ligament augmentation technique utilizing polyethylene tape is an effective technique to slow progression of the PJA and lower the risk for proximal junctional disease in ASD surgery.

Citations

Citations to this article as recorded by  Crossref logo
  • Differential Risk Factors for Proximal Junctional Kyphosis Between T8-T10 and T11-L1 Upper Instrumented Vertebrae in Adult Spinal Deformity
    Se-Jun Park, Jin-Sung Park, Dong-Ho Kang, Chong-Suh Lee
    Neurosurgery.2026;[Epub]     CrossRef
  • Proximal Junctional Kyphosis Prevention in Adult Spinal Deformity Surgery: A Technical Review of Tethering and Adjunctive Strategies
    Paritash Tahmasebpour, Pawel P. Jankowski, Jason Liang, Joshua Lin, Kyriakos D. Chatzis, Peter S. Tretiakov, Spencer Matthews, Louis Boissiere, John F. Burke, Christopher I. Shaffrey, Aaron Hockley, Peter Passias
    Operative Neurosurgery.2026;[Epub]     CrossRef
  • Clinical Outcomes and Mechanical Complications After Adult Spinal Deformity Surgery in Patients Aged 80 Years or Older: A Propensity Score-Matched Comparative Study
    Kai Inoue, Atsuyuki Kawabata, Jun Hashimoto, Takayuki Motoyoshi, Kurando Utagawa, Yu Matsukura, Takuya Oyaizu, Takashi Hirai, Hiroaki Onuma, Satoru Egawa, Kentaro Yamada, Shingo Morishita, Kazuo Kusano, Kazuyuki Otani, Shigeo Shindo, Toshitaka Yoshii
    Global Spine Journal.2026;[Epub]     CrossRef
  • Proximal junctional kyphosis above long spinal fusions
    Léonard Chatelain, Abbas Dib, Louise Ponchelet, Emmanuelle Ferrero
    Orthopaedics & Traumatology: Surgery & Research.2025; 111(1): 104065.     CrossRef
  • Effects of Transverse Process Hook Fixation for Preventing Proximal Junctional Kyphosis/Failure in Adult Spinal Deformity Surgery: A Multiple Regression Analysis Adjusting for Confounding Factors
    Se-Jun Park, Jin-Sung Park, Dong-Ho Kang, Minwook Kang, Kyunghun Jung, Chong-Suh Lee
    Global Spine Journal.2025; 15(7): 3138.     CrossRef
  • Risk Factor Analysis for Proximal Junctional Kyphosis in Neuromuscular Scoliosis: A Single-Center Study
    Tobias Lange, Kathrin Boeckenfoerde, Georg Gosheger, Sebastian Bockholt, Albert Schulze Bövingloh
    Journal of Clinical Medicine.2025; 14(11): 3646.     CrossRef
  • Posterior Ligamentous Augmentation is Associated With Reduced Rates of Proximal Junctional Kyphosis and Failure in Adult Spinal Deformity Surgery
    Pavlos Texakalidis, Stavros Matsoukas, Mykhaylo Krushelnytskyy, Kevin Swong, Najib El Tecle, Tyler R. Koski, Nader S. Dahdaleh
    Spine.2025; 50(13): 932.     CrossRef
  • Efficacy of Proximal Junctional Tethering in Spinal Fusion Surgery for Preventing Proximal Junctional Kyphosis and Proximal Junctional Failure: A Meta-analysis
    Yu-Chi Hsu, Hsuan-Tung Lee, Ying-Fong Su, Yang-Ching Chen, Serena S. Hu, Ching-Chi Hsu, Pei-I Tsai, Wei-Bin Hsu, Den-Tai Lin, Ching-Yu Lee, Tsung-Jen Huang, Tan Lam Minh Nguyen, Meng-Huang Wu
    Neurospine.2025; 22(3): 663.     CrossRef
  • Functional Alignment Within the Fusion in Adult Spinal Deformity (ASD) Improves Outcomes and Minimizes Mechanical Failures
    Fares Ani, Ethan W. Ayres, Alex Soroceanu, Gregory M. Mundis, Justin S. Smith, Jeffrey L. Gum, Alan H. Daniels, Eric O. Klineberg, Christopher P. Ames, Shay Bess, Christopher I. Shaffrey, Frank J. Schwab, Virginie Lafage, Themistocles S. Protopsaltis
    Spine.2024; 49(6): 405.     CrossRef
  • An evidence based conceptual framework for the multifactorial understanding of proximal junctional kyphosis
    Pearce B. Haldeman, Samuel R. Ward, Joseph Osorio, Bahar Shahidi
    Brain and Spine.2024; : 102807.     CrossRef
  • Re-Evaluating the Long-Term Efficacy of Semi-Rigid Fixation Using a Nitinol Spring Rod in Lumbar Surgery: A Retrospective Study on an Effective Alternative for Reducing Adjacent Segment Disease
    Hyun-Jun Jang, Bong-Ju Moon, Dong-Kyu Chin
    Applied Sciences.2024; 14(11): 4574.     CrossRef
  • Cyphose jonctionnelle proximale au-dessus des fusions rachidiennes étendues
    Léonard Chatelain, Abbas Dib, Louise Ponchelet, Emmanuelle Ferrero
    Revue de Chirurgie Orthopédique et Traumatologique.2024; 110(6): 761.     CrossRef
  • Proximal Junctional Kyphosis or Failure After Adult Spinal Deformity Surgery - Review of Risk Factors and Its Prevention
    Byung-Jou Lee, Sung Soo Bae, Ho Young Choi, Jin Hoon Park, Seung-Jae Hyun, Dae Jean Jo, Yongjae Cho
    Neurospine.2023; 20(3): 863.     CrossRef
  • Proximal junctional kyphosis: What we didn't know, what we think we know, and what we need to know
    Austin C. Kaidi, Justin S. Smith, Han Jo Kim
    Seminars in Spine Surgery.2023; 35(4): 101065.     CrossRef
  • Introduction of a New Radiographic Parameter to Predict Proximal Junctional Kyphosis in Adult Spinal Deformity: UIVPTA (Uppermost Instrumented Vertebra-Pelvic Tilt Angle)
    Se-Jun Park, Chong-Suh Lee, Jin-Sung Park, Tae Soo Shin
    Neurospine.2023; 20(3): 969.     CrossRef
  • Proximal Junctional Failure in Adult Spinal Deformity Surgery: An In-depth Review
    Mitsuru Yagi, Kento Yamanouchi, Naruhito Fujita, Haruki Funao, Shigeto Ebata
    Neurospine.2023; 20(3): 876.     CrossRef
  • Clinical Issues in Indication, Correction, and Outcomes of the Surgery for Neuromuscular Scoliosis: Narrative Review in Pedicle Screw Era
    Hak Sun Kim, Ji Won Kwon, Kun-Bo Park
    Neurospine.2022; 19(1): 177.     CrossRef
  • Clinically relevant biomechanical properties of three different fixation techniques of the upper instrumented vertebra in deformity surgery
    Edin Nevzati, Manuel Moser, Nick Dietz, Burt Yaszay, Lawrence G. Lenke, Mazda Farshad, Varun Arvind, Samuel K. Cho, Alexander Spiessberger
    Spine Deformity.2022; 10(5): 1017.     CrossRef
  • Association between lower Hounsfield units and proximal junctional kyphosis and failure at the upper thoracic spine
    Anthony L. Mikula, Nikita Lakomkin, Zach Pennington, Zachariah W. Pinter, Ahmad Nassr, Brett Freedman, Arjun S. Sebastian, Kingsley Abode-Iyamah, Mohamad Bydon, Christopher P. Ames, Jeremy L. Fogelson, Benjamin D. Elder
    Journal of Neurosurgery: Spine.2022; 37(5): 694.     CrossRef
  • The efficacy of prophylactic vertebroplasty for preventing proximal junctional complications after spinal fusion: a systematic review
    Roman Rahmani, Milo Sanda, Erin Sheffels, Amy Singleton, Samuel D. Stegelmann, Bernadette Kane, Thomas G. Andreshak
    The Spine Journal.2022; 22(12): 2050.     CrossRef
  • Proximal junctional kyphosis in adult spinal deformity: An up-to-date review
    Abduljabbar Alhammoud, Paul D. Korytkowski, William F. Lavelle, Umesh S. Metkar
    Seminars in Spine Surgery.2022; 34(4): 100992.     CrossRef
  • Influence of configuration and anchor in ligamentous augmentation to prevent proximal junctional kyphosis: A finite element study
    Wei Liu, Lei Zang, Nan Kang, Lihui Yang, Likun An, Wenyi Zhu, Yong Hai
    Frontiers in Bioengineering and Biotechnology.2022;[Epub]     CrossRef
  • 9,619 View
  • 151 Download
  • 18 Web of Science
  • 22 Crossref