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"Jeong Yoon Park"

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Clinical Study – Cervical Spine

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Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion
Neurospine. 2025;22(4):937-948.   Published online December 31, 2025
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Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion
Neurospine. 2025;22(4):937-948.   Published online December 31, 2025
Close
Objective
To evaluate the clinical significance of a negative K-line in the neck flexion position (FK-line [-]), which indicates that cervical ossification of the posterior longitudinal ligament (OPLL) crosses the K-line during flexion, and to compare surgical outcomes between laminoplasty (LP) and laminectomy with fusion (LF) for multilevel FK-line (-) cervical OPLL.
Methods
A total of 349 patients with multiple cervical OPLL who underwent posterior decompression surgery (LP or LF) with a minimum of 2 years of follow-up were stratified by FK-line status. Clinical and radiological parameters were compared between the FK-line (+) and FK-line (-) groups. Subgroup analysis of FK-line (-) patients evaluated the efficacy of LP versus LF. Multivariate regression identified predictors of neurological recovery.
Results
Patients with FK-line (-) OPLL exhibited a smaller FK-line distance, more kyphotic alignment, greater cervical flexion, and lower recovery ratios compared to those with FK-line (+). In the FK-line (-) subgroup, LF achieved a significantly greater increase in FK-line distance, better correction of the flexion angle, and more neurological recovery than LP. Multivariate analyses identified postoperative FK-line distance, C2–7 flexion angle, and preoperative dynamic extension reserve as independent predictors of neurological outcomes.
Conclusion
FK-line status reflects the sagittal cord position and predicts surgical outcomes in cervical OPLL. In FK-line (-) patients, LF provides better neurological recovery and more effective posterior cord shift and kyphotic alignment correction than LP. Incorporating FK-line assessment to guide surgical planning could improve individualized treatment outcomes for multilevel OPLL.

Citations

Citations to this article as recorded by  Crossref logo
  • A Commentary on “Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion”
    John H. Chi
    Neurospine.2025; 22(4): 951.     CrossRef
  • A Commentary on “Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion”
    Yutaro Kanda
    Neurospine.2025; 22(4): 949.     CrossRef
  • From the Editor-in-Chief: Featured Articles in the December 2025 Issue
    Inbo Han
    Neurospine.2025; 22(4): 877.     CrossRef
  • 1,284 View
  • 73 Download
  • 3 Web of Science
  • 3 Crossref

Cervical Spine

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The Role of K-Line and Canal-Occupying Ratio in Surgical Outcomes for Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Retrospective Multicenter Study
Neurospine. 2025;22(2):337-348.   Published online June 30, 2025
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The Role of K-Line and Canal-Occupying Ratio in Surgical Outcomes for Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Retrospective Multicenter Study
Neurospine. 2025;22(2):337-348.   Published online June 30, 2025
Close
Objective
To evaluate the impact of the K-line and canal-occupying ratio (COR) on surgical outcomes in patients with multilevel cervical ossification of the posterior longitudinal ligament (OPLL).
Methods
Patients with cervical myelopathy due to multilevel OPLL who underwent decompression surgery (anterior or posterior) from 2013 to 2022, with 2-year minimum follow-up, were enrolled. Radiological evaluations included K-line, COR, OPLL type/level, and cervical parameters (C2 slope [C2S], T1 slope [T1S], K-line tilt). Clinical outcomes included Japanese Orthopaedic Association (JOA) score and neck-pain visual analogue scale. Patients were categorized by K-line status (+/-) and COR (<50% or ≥50%).
Results
Among 575 patients, JOA recovery was significantly better in the K-line (+) and in low COR (<50%). In high COR (≥50%), K-line (-) was associated with poorer recovery. In low COR, outcomes were similar regardless of K-line. Anterior decompression with fusion (ADF) yielded the best outcomes. Laminoplasty (LP) was optimal for COR ≥50% and/or K-line (+), while laminectomy with fusion (LF) was better for COR ≥50% and K-line (-). In high COR, K-line was influenced by cervical alignment, C2S, and T1S, while in low COR, it was mainly affected by COR percentage.
Conclusion
Combining K-line and COR is essential for surgical planning in multilevel OPLL. When COR is high, K-line plays a significant role in predicting neurological recovery. ADF led to superior recovery, whereas for patients with K-line (-) and high COR, LF offered better results than LP. Cervical parameters at high COR influence the K-line more.

Citations

Citations to this article as recorded by  Crossref logo
  • Evaluating the demographics and complications of North American surgical patients with ossification of the posterior longitudinal ligament
    Aaron Phung, Justin Hyde, Justin Azmoodeh, Theodore Quan, Lancelot Benn, Christopher P. Bellaire, Oliver Tannous, Joseph Ferguson, Seyed B Kalantar, David Weiner, Andrew Mo, Fred Mo, Sean Bae, Ala Alshomali, Crisanto L. Macaraeg, Kevin Yoon, Jonathan P. J
    Journal of Clinical Neuroscience.2026; 144: 111790.     CrossRef
  • Radiological assessment in cervical spine myelopathy
    Shanmuganathan Rajasekaran, Gnanaprakash Gurusamy, Pushpa Bhari Thippeswamy, Karthik Ramachandran, Stefano Conti
    Journal of Clinical Orthopaedics and Trauma.2026; 72: 103301.     CrossRef
  • C2-Involving Cervical Ossification of the Posterior Longitudinal Ligament (OPLL): Dome-like Laminoplasty Versus Laminectomy With Fusion
    Jun Jae Shin, Sun Joon Yoo, Se Jun Park, Dong Kyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Joongkyum Shin, Yoon Ha
    Global Spine Journal.2026;[Epub]     CrossRef
  • Dynamic K-Line Status and Surgical Outcomes in Multilevel Cervical OPLL: A Multicenter Comparative Study
    Jun Jae Shin, Sun Joon Yoo, Se Jun Park, Dong Kyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Chang Kyu Lee, Keung Nyun Kim, Tae Woo Kim, Yoon Ha
    Journal of Clinical Medicine.2026; 15(2): 520.     CrossRef
  • A comparative study on surgical management of long-course symptomatic cervical OPLL between anterior en bloc resection and posterior laminectomy with instrumented fusion
    Kefu Chen, Yiwei Lu, Shu Liu, Lianshun Jia, Xingcheng Dong, Tianwen Ye
    BMC Musculoskeletal Disorders.2026;[Epub]     CrossRef
  • Reduction of Spinal Cord Cross-Sectional Area Is Associated With Myelopathy in Severe Cervical Ossification of the Posterior Longitudinal Ligaments
    Hyun-Jun Jang, Dong-Kyu Kim, Bong-Ju Moon, Kyung-Hyun Kim, Jeong-Yoon Park, Sung-Uk Kuh, Keun-Su Kim, Yong-Eun Cho, Dong-Kyu Chin
    Neurosurgery.2026;[Epub]     CrossRef
  • Spinal cord extracellular matrix hydrogel enhances organoid maturation and functional regeneration after spinal cord injury
    Junghoon Kim, Songzi Zhang, Joon-Hyuk Jung, Mi-Jeong Lee, Inbo Han, Seung-Woo Cho
    Materials Today Bio.2026; 38: 103168.     CrossRef
  • Surgical Technique and Technical Pearls of O-arm Navigation-assisted Anterior Cervical Corpectomy and Fusion for Cervical Ossification of the Posterior Longitudinal Ligament (OPLL)
    Yusuke Nishimura
    Spinal Surgery.2026; 40(1): 8.     CrossRef
  • Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion
    Jun Jae Shin, Sun Joon Yoo, Se Jun Park, Dong Kyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Chang Kyu Lee, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Joongkyum Shin, Yoon Ha
    Neurospine.2025; 22(4): 937.     CrossRef
  • 8,895 View
  • 249 Download
  • 9 Web of Science
  • 9 Crossref

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Predicting Mechanical Complications After Adult Spinal Deformity Operation Using a Machine Learning Based on Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density
Neurospine. 2023;20(1):265-274.   Published online March 31, 2023
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Predicting Mechanical Complications After Adult Spinal Deformity Operation Using a Machine Learning Based on Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density
Neurospine. 2023;20(1):265-274.   Published online March 31, 2023
Close
Objective
This study aimed to create an ideal machine learning model to predict mechanical complications in adult spinal deformity (ASD) surgery based on GAPB (modified global alignment and proportion scoring with body mass index and bone mineral density) factors.
Methods
Between January 2009 and December 2018, 238 consecutive patients with ASD, who received at least 4-level fusions and were followed-up for ≥ 2 years, were included in the study. The data were stratified into training (n = 167, 70%) and test (n = 71, 30%) sets and input to machine learning algorithms, including logistic regression, random forest gradient boosting system, and deep neural network.
Results
Body mass index, bone mineral density, the relative pelvic version score, the relative lumbar lordosis score, and the relative sagittal alignment score of the global alignment and proportion score were significantly different in the training and test sets (p < 0.05) between the complication and no complication groups. In the training set, the area under receiver operating characteristics (AUROCs) for logistic regression, gradient boosting, random forest, and deep neural network were 0.871 (0.817–0.925), 0.942 (0.911–0.974), 1.000 (1.000–1.000), and 0.947 (0.915–0.980), respectively, and the accuracies were 0.784 (0.722–0.847), 0.868 (0.817–0.920), 1.000 (1.000–1.000), and 0.856 (0.803–0.909), respectively. In the test set, the AUROCs were 0.785 (0.678–0.893), 0.808 (0.702–0.914), 0.810 (0.710–0.910), and 0.730 (0.610–0.850), respectively, and the accuracies were 0.732 (0.629–0.835), 0.718 (0.614–0.823), 0.732 (0.629–0.835), and 0.620 (0.507–0.733), respectively. The random forest achieved the best predictive performance on the training and test dataset.
Conclusion
This study created a comprehensive model to predict mechanical complications after ASD surgery. The best prediction accuracy was 73.2% for predicting mechanical complications after ASD surgery.

Citations

Citations to this article as recorded by  Crossref logo
  • Determining the risk factors for postoperative mechanical complication in degenerative scoliosis: a machine learning approach based on musculoskeletal metrics
    Jie Li, Zhen Tian, Yinyu Fang, Zhong He, Yanjie Xu, Hui Xu, Zezhang Zhu, Yong Qiu, Zhen Liu
    European Spine Journal.2026; 35(1): 156.     CrossRef
  • Development and validation of a deep learning–powered system for multi-version global alignment and proportion score to predict mechanical complications after adult degenerative scoliosis surgery
    Qifeng Lan, Shanshan Liu, Cheng Zhang, Chenyi Guo, Yiming Shi, Jian He, Xingyu Zhou, Jiaheng Shang, Qiang Qi, Zhaoqing Guo, Zhuoran Sun, Siyu Zhou, Ji Wu, Nanfang Xu, Weishi Li
    European Spine Journal.2026; 35(2): 375.     CrossRef
  • Proximal Junctional Kyphosis Prevention in Adult Spinal Deformity Surgery: A Technical Review of Tethering and Adjunctive Strategies
    Paritash Tahmasebpour, Pawel P. Jankowski, Jason Liang, Joshua Lin, Kyriakos D. Chatzis, Peter S. Tretiakov, Spencer Matthews, Louis Boissiere, John F. Burke, Christopher I. Shaffrey, Aaron Hockley, Peter Passias
    Operative Neurosurgery.2026;[Epub]     CrossRef
  • Predicting postoperative mechanical complications with the ethnicity-adjusted global alignment and proportion score in degenerative scoliosis: does paraspinal muscle degeneration matter?
    Peiyu Li, Jie Li, Abdukahar Kiram, Zhen Tian, Xing Sun, Xiaodong Qin, Benlong Shi, Yong Qiu, Zhen Liu, Zezhang Zhu
    The Spine Journal.2025; 25(2): 347.     CrossRef
  • Uso de inteligencia artificial para predecir complicaciones en cirugías de columna toracolumbar degenerativa: revisión sistemática
    G. Ricciardi, J.I. Cirillo Totera, R. Pons Belmonte, L. Romero Valverde, F. López Muñoz, A. Manríquez Díaz
    Revista Española de Cirugía Ortopédica y Traumatología.2025; 69(5): 446.     CrossRef
  • Risk Factors of 90-Day Unplanned Readmission After Lumbar Spine Surgery for Degenerative Lumbar Disk Disease: A Systematic Review and Meta-Analysis
    Jeong In Seol, Jeong Hoon Yoo, Hyeon Gyu Sung, Hyun Ho Park, Sung Hyeon Noh
    Neurosurgery.2025; 97(4): 908.     CrossRef
  • AI and machine learning in paediatric spine deformity surgery
    Mohsin Khan, Kaustubh Ahuja, Athanasios I Tsirikos
    Bone & Joint Open.2025; 6(5): 569.     CrossRef
  • Novel risk factors and personalized risk calculator for predicting proximal junctional kyphosis after adult spinal deformity surgery
    Qijun Wang, Zheng Wang, Dongfan Wang, Xuan Zhao, Xiaolong Chen, Shibao Lu
    The Bone & Joint Journal.2025; 107-B(8): 829.     CrossRef
  • [Translated article] Use of artificial intelligence to predict complications in degenerative thoracolumbar spine surgery: A systematic review
    G. Ricciardi, J.I. Cirillo Totera, R. Pons Belmonte, L. Romero Valverde, F. López Muñoz, A. Manríquez Díaz
    Revista Española de Cirugía Ortopédica y Traumatología.2025; 69(5): T446.     CrossRef
  • Applications of Artificial Intelligence in the Diagnosis and Treatment of Pediatric Congenital malformations: Recent Advances
    鑫 王
    Advances in Clinical Medicine.2025; 15(09): 91.     CrossRef
  • The predictive value of the global alignment and proportion (GAP) score for mechanical complications following adult spinal deformity surgery: A systematic review and meta-analysis
    Vinicius Ricieri Ferraz, Guilherme Santos Piedade, Carlos R. Goulart, Maria Fernanda Ricieri Ferraz Franco de Souza, Marcelo Ochoa Coelho de Souza Furlan, Philippe A. Mercier, Tobias A. Mattei
    North American Spine Society Journal (NASSJ).2025; 24: 100816.     CrossRef
  • Predicting proximal junctional failure in adult spinal deformity patients using machine learning models based on spinal alignment parameters
    Akihiko Hiyama, Daisuke Sakai, Hiroyuki Katoh, Masato Sato, Masahiko Watanabe
    Scientific Reports.2025;[Epub]     CrossRef
  • Evaluating Computer Vision, Large Language, and Genome-Wide Association Models in a Limited Sized Patient Cohort for Pre-Operative Risk Stratification in Adult Spinal Deformity Surgery
    Ethan Schonfeld, Aaradhya Pant, Aaryan Shah, Sina Sadeghzadeh, Dhiraj Pangal, Adrian Rodrigues, Kelly Yoo, Neelan Marianayagam, Ghani Haider, Anand Veeravagu
    Journal of Clinical Medicine.2024; 13(3): 656.     CrossRef
  • Lower Hounsfield Units at the Planned Lowest Instrumented Vertebra Is an Independent Risk Factor for Complications Following Adult Cervical Deformity Surgery
    Tyler K. Williamson, Ezekial J. Koslosky, Jordan Lebovic, Stephane Owusu-Sarpong, Peter Tretiakov, Jamshaid Mir, Pooja Dave, Andrew J. Schoenfeld, Bassel G. Diebo, Heiko Koller, Renaud Lafage, Virginie Lafage, Peter G. Passias
    Clinical Spine Surgery.2024; 37(10): E503.     CrossRef
  • Commentary on “Performance of a Large Language Model in the Generation of Clinical Guidelines for Antibiotic Prophylaxis in Spine Surgery”
    Sun-Ho Lee
    Neurospine.2024; 21(1): 147.     CrossRef
  • Deep Learning Method for Precise Landmark Identification and Structural Assessment of Whole-Spine Radiographs
    Sung Hyun Noh, Gaeun Lee, Hyun-Jin Bae, Ju Yeon Han, Su Jeong Son, Deok Kim, Jeong Yeon Park, Seung Kyeong Choi, Pyung Goo Cho, Sang Hyun Kim, Woon Tak Yuh, Su Hun Lee, Bumsoo Park, Kwang-Ryeol Kim, Kyoung-Tae Kim, Yoon Ha
    Bioengineering.2024; 11(5): 481.     CrossRef
  • Research of Global Tilt and Functional Independence: Insights into Spinal Health of Older Women
    Yu-Chieh Chiu, Ping-Chiao Tsai, Ssu-Hsien Lee, Wen-Tien Wu, Tzai-Chiu Yu, Ru-Ping Lee, Ing-Ho Chen, Jen-Hung Wang, Kuang-Ting Yeh
    Bioengineering.2024; 11(5): 493.     CrossRef
  • Trends in degenerative lumbar spinal surgery during the early COVID-19 pandemic in Republic of Korea: A national study utilizing the national health insurance database
    Woon Tak Yuh, Jinhee Kim, Mi-Sook Kim, Jun-Hoe Kim, Young Rak Kim, Sum Kim, Chun Kee Chung, Chang-Hyun Lee, Sung Bae Park, Kyoung-Tae Kim, John M. Rhee, Young San Ko, Chi Heon Kim, Kentaro Yamada
    PLOS ONE.2024; 19(6): e0305128.     CrossRef
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    Nader Toossi, Ozhan Jerry
    Artificial Intelligence Surgery.2024; 4(3): 258.     CrossRef
  • Prediction of postoperative mechanical complications in ASD patients based on total sequence and proportional score of spinal sagittal plane
    Wenbin Jiang, Huagang Shi, Tao Gu, Zonglin Cai, Qinglong Li
    SLAS Technology.2024; 29(6): 100222.     CrossRef
  • Classification of lumbar spine disorders using large language models and MRI segmentation
    Rongpeng Dong, Xueliang Cheng, Mingyang Kang, Yang Qu
    BMC Medical Informatics and Decision Making.2024;[Epub]     CrossRef
  • Proximal Junctional Failure Development Despite Achieving Ideal Sagittal Correction According to Age-Adjusted Alignment Target in Patients With Adult Spinal Deformity: Risk Factor Analysis of 196 Cases Undergoing Low Thoracic to Pelvic Fusion
    Se-Jun Park, Jin-Sung Park, Dong-Ho Kang, Minwook Kang, Kyunghun Jung, Chong-Suh Lee
    Neurospine.2024; 21(4): 1080.     CrossRef
  • Complication Rates and Utilization Trends of 3-Level Posterior Column Osteotomy Compared to Single-Level Pedicle Subtraction Osteotomy
    Emily S. Mills, Kevin Mertz, Ethan Faye, Jennifer A. Bell, Andy T. Ton, Jeffrey C. Wang, Ram K. Alluri, Raymond J. Hah
    Neurospine.2023; 20(2): 662.     CrossRef
  • Proximal Junctional Failure in Adult Spinal Deformity Surgery: An In-depth Review
    Mitsuru Yagi, Kento Yamanouchi, Naruhito Fujita, Haruki Funao, Shigeto Ebata
    Neurospine.2023; 20(3): 876.     CrossRef
  • Proximal Junctional Kyphosis or Failure After Adult Spinal Deformity Surgery - Review of Risk Factors and Its Prevention
    Byung-Jou Lee, Sung Soo Bae, Ho Young Choi, Jin Hoon Park, Seung-Jae Hyun, Dae Jean Jo, Yongjae Cho
    Neurospine.2023; 20(3): 863.     CrossRef
  • Development and Validation of an Online Calculator to Predict Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery Using Machine Learning
    Chang-Hyun Lee, Dae-Jean Jo, Jae Keun Oh, Seung-Jae Hyun, Jin Hoon Park, Kyung Hyun Kim, Jun Seok Bae, Bong Ju Moon, Chang-Kyu Lee, Myoung Hoon Shin, Hyun Jun Jang, Moon-Soo Han, Chi Heon Kim, Chun Kee Chung, Seung-Myung Moon
    Neurospine.2023; 20(4): 1272.     CrossRef
  • Commentary on “Development and Validation of an Online Calculator to Predict Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery Using Machine Learning”
    In Ho Han
    Neurospine.2023; 20(4): 1281.     CrossRef
  • 8,006 View
  • 253 Download
  • 25 Web of Science
  • 27 Crossref

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Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density Analysis in Global Alignment and Proportion Score of Each 3 Categories for Predicting Mechanical Complications After Adult Spinal Deformity Surgery
Neurospine. 2021;18(3):484-491.   Published online September 30, 2021
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Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density Analysis in Global Alignment and Proportion Score of Each 3 Categories for Predicting Mechanical Complications After Adult Spinal Deformity Surgery
Neurospine. 2021;18(3):484-491.   Published online September 30, 2021
Close
Objective
This study aimed to analyze the prediction rate of the modified Global Alignment and Proportion (GAP) scoring system with body mass index and bone mineral density (GAPB) in each GAP of the 3 categories.
Methods
Between January 2009 and December 2016, 203 consecutive patients with adult spinal deformity (ASD) underwent corrective fusion of more than 4 levels and were followedup for more than 2 years. As a validation of the GAPB, the GAPB was divided into tertiles (Q1, Q2, Q3) for each section of the GAP score. Each patient’s GAP score and GAPB system complication rate were examined.
Results
Of the 203 patients, 89 patients (44%) developed mechanical complications after ASD surgery. A GAP score analysis of the patients found that 42 patients were proportioned, 85 patients were moderately disproportioned, and 76 patients were severely disproportioned. Mechanical complications occurred with increasing GAPB in the proportioned group, but were not statistically significant (p = 0.0534). However, mechanical complications occurred in a statistically significant manner in the moderately disproportioned and severely disproportioned groups as GAPB increased (p < 0.001).
Conclusion
The GAPB system showed improved predictability for mechanical complications after surgery for ASD in each category of the GAP score.

Citations

Citations to this article as recorded by  Crossref logo
  • Machine learning clustering reveals risk factors of mechanical complications requiring revision in adult spinal deformity surgery: a 2-year follow-up study
    Alice Baroncini, Daniel Larrieu, Anouar Bourghli, Javier Pizones, Ferran Pellisè, Frank Kleinstueck, Ahmet Alanay, Yann Philippe Charles, Cecile Roscop, Louis Boissiere, Ibrahim Obeid
    European Spine Journal.2026; 35(1): 167.     CrossRef
  • Cost Benefit of Implementation of Risk Stratification Models for Adult Spinal Deformity Surgery
    Peter G. Passias, Tyler K. Williamson, Nicholas A. Kummer, Ferran Pellisé, Virginie Lafage, Renaud Lafage, Miguel Serra-Burriel, Justin S. Smith, Breton Line, Shaleen Vira, Jeffrey L. Gum, Sleiman Haddad, Francisco Javier Sánchez Pérez-Grueso, Andrew J. S
    Global Spine Journal.2025; 15(2): 818.     CrossRef
  • Predicting postoperative mechanical complications with the ethnicity-adjusted global alignment and proportion score in degenerative scoliosis: does paraspinal muscle degeneration matter?
    Peiyu Li, Jie Li, Abdukahar Kiram, Zhen Tian, Xing Sun, Xiaodong Qin, Benlong Shi, Yong Qiu, Zhen Liu, Zezhang Zhu
    The Spine Journal.2025; 25(2): 347.     CrossRef
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    Zeyad Daher, Luke L. Jouppi, Bryan G. Anderson, Clifford Pierre, Donald David Davis, Neel Patel, Julius Gerstmeyer, Gautam Rao, Daniel Norvell, Giorgio Cracchiolo, Amir Abdul-Jabbar, Rod Oskouian, Jens R. Chapman
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    Global Spine Journal.2025;[Epub]     CrossRef
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    Vinicius Ricieri Ferraz, Guilherme Santos Piedade, Carlos R. Goulart, Maria Fernanda Ricieri Ferraz Franco de Souza, Marcelo Ochoa Coelho de Souza Furlan, Philippe A. Mercier, Tobias A. Mattei
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    Seung-Jae Hyun, Sungjae An, Byoung-Joo Park, Jae-Koo Lee, Seung Heon Yang, Ki-Jeong Kim
    Operative Neurosurgery.2024; 26(3): 268.     CrossRef
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    Minseong Cho, Sanghoon Lee, Ho-Joong Kim
    European Spine Journal.2024; 33(4): 1311.     CrossRef
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    Javier Pizones, Jeffrey Hills, Michael Kelly, Caglar Yilgor, Lucía Moreno-Manzanaro, Francisco Javier Sánchez Perez-Grueso, Frank Kleinstück, Ibrahim Obeid, Ahmet Alanay, Ferran Pellisé
    Spine Deformity.2024; 12(4): 1127.     CrossRef
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    Sung Hyun Noh, Gaeun Lee, Hyun-Jin Bae, Ju Yeon Han, Su Jeong Son, Deok Kim, Jeong Yeon Park, Seung Kyeong Choi, Pyung Goo Cho, Sang Hyun Kim, Woon Tak Yuh, Su Hun Lee, Bumsoo Park, Kwang-Ryeol Kim, Kyoung-Tae Kim, Yoon Ha
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    Jeffrey Hills, Gregory M. Mundis, Eric O. Klineberg, Justin S. Smith, Breton Line, Jeffrey L. Gum, Themistocles S. Protopsaltis, D. Kojo Hamilton, Alex Soroceanu, Robert Eastlack, Pierce Nunley, Khaled M. Kebaish, Lawrence G. Lenke, Richard A. Hostin, Mun
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  • 9,565 View
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Characteristics and Risk Factors of Rod Fracture Following Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis
Neurospine. 2021;18(3):447-454.   Published online September 30, 2021
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Characteristics and Risk Factors of Rod Fracture Following Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis
Neurospine. 2021;18(3):447-454.   Published online September 30, 2021
Close
Objective
The aim of study is to investigate the features and risk factors of rod fracture (RF) following adult spinal deformity (ASD) surgery.
Methods
We searched the PubMed, Embase, Web of Science, and Cochrane Library databases to identify relevant studies. Patient’s data including age, sex, body mass index (BMI), previous spine surgery, pedicle subtraction osteotomy (PSO), interbody fusion, fusion to the pelvis, smoking history, preoperative sagittal vertical axis (SVA), preoperative pelvic tilt (PT), preoperative pelvic incidence minus lumbar lordosis, preoperative thoracic kyphosis (TK), and change in the SVA were documented. Comparable factors were evaluated using odds ratio (OR) and weighted mean difference (WMD) with 95% confidence interval (CI).
Results
Seven studies were included. The overall incidence of RF following ASD surgery was 12%. Advanced age (WMD, 2.8; 95% CI, 1.01–4.59; p < 0.002), higher BMI (WMD, 1.98; 95% CI, 0.65–3.31; p = 0.004), previous spine surgery (OR, 1.47; 95% CI, 1.05–2.04; p = 0.02), PSO (OR, 2.28; 95% CI, 1.62–3.19; p < 0.0001), a larger preoperative PT (WMD, 6.17; 95% CI, 3.55–8.97; p < 0.00001), and a larger preoperative TK (WMD, 5.19; 95% CI, 1.41–8.98; p = 0.007) were identified as risk factors for incidence of RF.
Conclusion
The incidence of RF in patients following ASD surgery was 12%. Advanced age, higher BMI, previous spine surgery, and PSO were significantly associated with an increased occurrence of RF. A larger preoperative PT and TK were also identified as risk factors for occurrence of RF following ASD surgery.

Citations

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  • Striking a Balance: The Role of Alignment, Surgical Techniques, and Multi-Rod Constructs in Reducing Rate of Rod Fractures in Adult Spinal Deformity Surgery
    Schahin Salmanian, Jay Kumar, César Carballo Cuello, Diego Soto Rubio, Mark Greenberg, Erik Hayman, Mohsen Rostami, Puya Alikhani
    Global Spine Journal.2026; 16(4): 1754.     CrossRef
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    Clinical Orthopaedics & Related Research.2026; 484(5): 989.     CrossRef
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    Clinics in Orthopedic Surgery.2026; 18(2): 281.     CrossRef
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    Global Spine Journal.2025; 15(2): 498.     CrossRef
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    European Spine Journal.2024; 33(5): 1850.     CrossRef
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    European Spine Journal.2024; 33(5): 1857.     CrossRef
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Clinical Articles

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Bone Mineral Density Changes after Orchiectomy using a Scrotal Approach in Rats
Korean J Spine. 2015;12(2):55-59.   Published online June 30, 2015
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Bone Mineral Density Changes after Orchiectomy using a Scrotal Approach in Rats
Korean J Spine. 2015;12(2):55-59.   Published online June 30, 2015
Close
Objective

To investigate a suitable animal model for studies of male osteoporosis. Osteoporosis has a particularly high incidence in postmenopausal women, resulting in a substantial amount of research with respect to this disease in women. However, research on osteoporosis in men is still lacking.

Methods

Twenty 10-week-old male Sprague Dawley rats were used in this study, including 4 rats used to establish a baseline bone mineral density (BMD). The other 16 rats were divided into two groups: a sham surgery group (n=8), which underwent a sham operation, and an orchiectomized rat group (OCX) (n=8), which underwent bilateral OCX at 10 weeks of age. Bone mineral density was measured in 4 rats from both the sham surgery group and the OCX group 8 weeks after the surgery, while BMD in the remainder of the rats was measured 10 weeks post-surgery.

Results

Femoral BMD at 8 weeks post-surgery was found to be significantly lower in the OCX group compared to the sham group; a finding that was also similar 10 weeks post-surgery.

Conclusion

8 weeks after undergoing orchiectomy performed via a scrotal, white rats are a suitable model for studies of male osteoporosis.

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  • The antiosteoporotic effect of oxymatrine compared to testosterone in orchiectomized rats
    Anwaar M. Shaban, Eman A. Ali, Sara G. Tayel, Sara Kamal Rizk, Dalia F. El Agamy
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • Promotion of Bone Formation in a Rat Osteoporotic Vertebral Body Defect Model via Suppression of Osteoclastogenesis by Ectopic Embryonic Calvaria Derived Mesenchymal Stem Cells
    Yerin Yu, Somin Lee, Minsung Bock, Seong Bae An, Hae Eun Shin, Jong Seop Rim, Jun-oh Kwon, Kwang-Sook Park, Inbo Han
    International Journal of Molecular Sciences.2024; 25(15): 8174.     CrossRef
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    Ioannis Stratos, Ingmar Rinas, Konrad Schröpfer, Katharina Hink, Philipp Herlyn, Mario Bäumler, Tina Histing, Sven Bruhn, Brigitte Müller-Hilke, Michael D. Menger, Brigitte Vollmar, Thomas Mittlmeier
    Biomedicines.2023; 11(5): 1370.     CrossRef
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    Journal of Acupuncture Research.2022; 39(3): 234.     CrossRef
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    Vinícius de Paiva Gonçalves, Adriana Alicia Cabrera-Ortega, Jhonatan de Souza Carvalho, Dania Ramadan, Luís Carlos Spolidorio
    The Aging Male.2021; 24(1): 139.     CrossRef
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    Kyung A Back, Se Hwan Park, Jin Hwan Yoon
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    Marina Komrakova, Janek Nagel, Daniel Bernd Hoffmann, Wolfgang Lehmann, Arndt Friedrich Schilling, Stephan Sehmisch
    Calcified Tissue International.2020; 107(6): 593.     CrossRef
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    Hussein F. Sakr, Abdelaziz M. Hussein, Elsayed A. Eid, Ammar Boudaka, Lashin S. Lashin
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    Seong-Jun Ryu, Dal-Sung Ryu, Jong-Yeol Kim, Jeong-Yoon Park, Kyung-Hyun Kim, Dong-Kyu Chin, Keun-Su Kim, Yong-Eun Cho, Sung-Uk Kuh
    Yonsei Medical Journal.2016; 57(6): 1386.     CrossRef
  • 10,915 View
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A PET/CT-based Morphometric Study of Spinal Canal in Korean Young Adults: Anteroposterior Diameter from Cervical Vertebra to Sacrum
Korean J Spine. 2012;9(3):165-169.   Published online September 30, 2012
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A PET/CT-based Morphometric Study of Spinal Canal in Korean Young Adults: Anteroposterior Diameter from Cervical Vertebra to Sacrum
Korean J Spine. 2012;9(3):165-169.   Published online September 30, 2012
Close
Objective

To establish normative data for spinal canal AP diameter from cervical vertebra to sacrum in the Korean young and to assess the exposed spinal canal after laminectomy which was related with restenosis by post-laminectomy membrane formation.

Methods

From PET/CT, axial bone-window CT of 83 young adults (20-29 years) were obtained, and we measured AP diameters of C3, C5, C7, T1, T4, T8, T12, L1, L3, L5 and S1. We also measured exposed AP diameter of C3, C5, C7, T1 and T2 above imaginary line for laminectomy.

Results

The shortest mean AP diameter was at C5 (14.5±1.5 mm), and the longest was at S1 (17.4±2.3 mm). AP diameter increased from C3 (14.6±1.1 mm) to T1 (16.1±1.2 mm) at cervical spine. In the thoracic spine, the diameter gradually decreased from T1 (16.1±1.2 mm) to T8 (14.6±1.3 mm) and increased to T12 (16.7±1.2 mm). The diameter decreased from L1 (16.7±1.3 mm) to L3 (15.7±1.9 mm), and it increased to S1 (17.4±2.3 mm) at lumbar spine. Exposed AP diameter above imaginary line for laminectomy was the longest at C3 (4.8±1.2 mm) and gradually decreased to T1 (3.3±0.9 mm) and T2 (0 mm).

Conclusions

Spinal AP diameter was the shortest in the mid-cervical area (C5) and increased to the upper thoracic area. From the upper thoracic vertebra, the diameter gradually decreased to the mid-thoracic vertebra (T8) and then increased to the lower thoracic vertebra. Lumbar vertebra also was similar with thoracic vertebra. Below T2, there was no exposed dural sac after laminectomy. This means that restenosis by post-laminectomy membrane formation can occur above T1.

Citations

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    Hyeon Jae Jo, Sook-In Jung, Eu Suk Kim, Kyoung-Ho Song, Kyung-Hwa Park, Nam Joong Kim
    BMC Infectious Diseases.2026;[Epub]     CrossRef
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    Alexander Shao-Rong Pang, Fang Nian Joanne Lim, Pirateb Paramasivam Meenakshi Sundaram, Jacob Yoong-Leong Oh
    Spine.2026; 51(7): E169.     CrossRef
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    Soo-Im Jang, Soyoun Choi, Seung Ae Kim, Hoe Jong Jeong, Ja-Young Choi, Mi Ji Lee
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    Brian T. Ragel, Matthew McGehee, Nicolas Karvelas, Ahmed M. Raslan
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    Shinsuke Yoshida, Takaaki Suzuki, Masayuki Tanabe, Kazuo Saita
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    Interdisciplinary Neurosurgery.2023; 34: 101862.     CrossRef
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    Open Journal of Radiology.2017; 07(01): 45.     CrossRef
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  • 117 Download
  • 10 Crossref

Original Articles

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Surgical Treatment of Tuberculous Spondylitis: Retrospective Analysis of Risk Factors and 15 Year Experience of Single Medical Center in South Korea.
Korean J Spine. 2011;8(3):215-220.
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Surgical Treatment of Tuberculous Spondylitis: Retrospective Analysis of Risk Factors and 15 Year Experience of Single Medical Center in South Korea.
Korean J Spine. 2011;8(3):215-220.
Close
OBJECTIVE
Despite the development of society and improvement in public hygiene, the number of cases of tuberculous spondylitis (TS) has increased recently. This study was designed to analyze the risk factors and operation methods of TS.
METHODS
In this medical record-based retrospective study, there were 83 cases reviewed of instances where TS was operated in between 1996 to 2010 at one hospital. In order to observe a change according to times, the authors divided patients into three groups by five years. We used Cochran's Q test to compare between the groups.
RESULTS
The mean age of patients was 46.1+/-18.1 years, and 44.6% of the patients were male. The operated sites were mostly lumbar (42.2%) and thoracic (33.7%) spine. Eighteen patients (21.7%) had a history of pulmonary tuberculosis (TB), and only 15.6% had other underlying medical disorders. Between the groups, there were no statistically significant differences in age, gender, location, medical risk factors, or socioeconomic factors. The only two factors statistically significant were history of smoking and pulmonary TB. Operation methods have been changed from anterior approach to posterior approach. Visual analogue scale was improved significantly after the treatment (from 6.16 to 3.32) and postoperative satisfaction rate was 91.6%.
CONCLUSION
The number of patients operated due to TS has increased, and so does primary TS without pulmonary tuberculosis. A combination of surgical operation and medical treatment of the TS tends to have more favorable outcomes.
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The Clinical and Radiological Characteristics of Male Patients who Underwent Vertebroplasty Due to Osteoporotic Compression Fracture.
Korean J Spine. 2011;8(3):178-182.
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The Clinical and Radiological Characteristics of Male Patients who Underwent Vertebroplasty Due to Osteoporotic Compression Fracture.
Korean J Spine. 2011;8(3):178-182.
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OBJECTIVE
To investigate the clinical characteristics of male population who underwent vertebroplasty for osteoporotic compression fracture and evaluate the clinical, radiological outcomes compared to female group.
METHODS
The medical records and radiological data were reviewed in total 155 patients who underwent vertebroplasty for osteoporotic vertebral compression fracture from February 2006 to November 2009. We compared 32 male patients with 123 female patients in terms of preoperative factors, intraoperative factors, and clinical and radiologic outcomes.
RESULTS
The mean age of male group was 67.8~8.6 years and their mean T-score on bone mineral density (BMD) was -3.2+/-0.8. The mean age of female group was 71.8+/-8.9 years and their mean T-score was -3.7+/-0.7 (p=0.025 for age, p=0.002 for BMD). Male patients (21 out of 32, 65.6%) had more frequent traumatic event than female patients (51 out of 123, 41.5%) (p=0.012). The secondary osteoporosis was more frequently seen in male group than female group (53.1% vs 26.8%, p=0.005). The lump cement distribution pattern was found more frequently in male group than female group (46.9% vs 28.5%, p=0.040). There was no statistically significant difference between the two groups in clinical outcomes.
CONCLUSION
Male patients had significantly more risk factors for secondary osteoporosis and obvious traumatic event than female group. Clinicians should always be aware of secondary causes of osteoporosis and history of traumatic events in male patients with osteoporotic compression fracture and also pay attention to correct the cause of secondary osteoporosis and recommend anti-osteoporosis management.
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Case Report

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Recycling of Cervical Artificial Disc for the Symptomatic Adjacent Segment Disorder Combined with Instability on Total Disc Replacement Area: A Case Report.
Korean J Spine. 2010;7(3):206-211.
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Recycling of Cervical Artificial Disc for the Symptomatic Adjacent Segment Disorder Combined with Instability on Total Disc Replacement Area: A Case Report.
Korean J Spine. 2010;7(3):206-211.
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The authors describe the revision case of a 58-year-old man who presented with pain in the neck and both shoulders after C4-5 cervical total disc replacement (C-TDR) and C5-6 anterior cervical discectomy and fusion (ACDF), and in whom there was evidence of instability with sagittal translation at the C4-5 TDR level and of a herniated cervical disc (HCD) at the left side of C3-4. The revision surgery was performed as follows: previous plate removal at the C5-6 level, artificial disc removal and ACDF at the C4-5 level with cage and previous plate insertion, and TDR at the C3-4 level using the previously implanted C4/5 artificial disc. If instability develops at the level of an artificial disc, we perform additional posterior fusion or anterior removal of the artificial disc and fusion. However, if we encounter combined adjacent segment disc disease, we may reuse the unstable segment artificial disc at the adjacent segment and perform salvage anterior fusion on the unstable segment. This is the first report issued on the management of instability after previous C-TDR involving a switch to ACDF and the use of new TDR at the adjacent level. Furthermore, we conceptually recommend a solution to an emerging problem of adjacent segment disease due to the heterotopic ossification(HO) after C-TDR.
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