Neurospine

Regular Issue

The Clinical Outcomes of Cervical Spine Chordoma: A Nationwide Multicenter Retrospective Study: Hangeul Park, Yunhee Choi, Sungjoon Lee, Sun-Ho Lee, Eun-Sang Kim, Sun Woo Jang, Jin Hoon Park, Yunseong Cho, Giwuk Jang, Yoon Ha, Yun-Sik Dho, Heon Yoo, Sung Uk Lee, Seung-Ho Seo, Ki-Jeong Kim, Seil Sohn, Chun Kee Chung; Neurospine 2024;21(3):942-953. Published online September 30, 2024; DOI: https://doi.org/10.14245/ns.2448448.224

Abstract
PDF
Supplementary material
Cite this article

Cite this article

export

Copy Download

Format

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
BibTeX — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

The Clinical Outcomes of Cervical Spine Chordoma: A Nationwide Multicenter Retrospective Study

Neurospine. 2024;21(3):942-953. Published online September 30, 2024

DOI: https://doi.org/10.14245/ns.2448448.224

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
bib — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

The Clinical Outcomes of Cervical Spine Chordoma: A Nationwide Multicenter Retrospective Study

Neurospine. 2024;21(3):942-953. Published online September 30, 2024

DOI: https://doi.org/10.14245/ns.2448448.224

Close

Objective
Chordoma, a rare malignant tumor originating from embryonal notochord remnants, exhibits high resistance to conventional treatments, making surgical resection imperative. However, the factors influencing prognosis specifically for cervical spine chordoma have not been clearly identified. We investigate the prognosis of cervical spine chordoma with factors influential in a nationwide multicenter retrospective study.
Methods
This study included all patients diagnosed with cervical spine chordoma at 7 tertiary referral centers from January 1998 to March 2023, excluding those with clivus and thoracic spine chordomas extending into the cervical spine. Local recurrence (LR) was identified through follow-up magnetic resonance imaging, either as reappearance in completely resected tumors or regrowth in residual tumors. The study assessed LR and overall survival, analyzing factors influencing LR and death.
Results
Forty-five patients with cervical spine chordoma had a mean age of 46.4 years. Over a median follow-up of 52 months, LR and distant metastasis were observed in 21 (46.7%) and 4 patients (8.9%), respectively, and 16 patients (36%) were confirmed dead. The 5-year and 10-year cumulative LR rates were 51.3% and 60%, respectively, while the 5-year and 10-year survival rates were 82% and 53%. Age was the only significant factor affecting mortality (hazard ratio, 1.04; 95% confidence interval, 1.04–1.07; p=0.015). Notably, the degree of resection and adjuvant therapy did not statistically significantly impact local tumor control and mortality.
Conclusion
This study, the largest multicenter retrospective analysis of cervical spine chordoma in Korea, identified age as the only factor significantly affecting patient survival.

Citations

Citations to this article as recorded by

Cervical Vertebral Body Implant Modification Accommodating Vertebral Artery Aneurysm Clips: A Case Report
Robert Rothrock, Vitaly Siomin, Rupesh Kotecha, Starlie C Belnap, Michael McDermott
Cureus.2026;[Epub] CrossRef
SURGICAL MANAGEMENT OF ANTERIORLY LOCATED TUMORS AT THE CRANIOVERTEBRAL JUNCTION: ADVANCES AND CHALLENGES
ANTONIO VINICIUS DA SILVA GONÇALVES DA ROCHA, MARIANA CHANTRE-JUSTINO, OCTAVIO AUGUSTO TOMÉ DA SILVA, DAVI SOÉJIMA CORREIA RAMALHO, ALDERICO GIRÃO CAMPOS DE BARROS, ULLYANOV TOSCANO, LUIS E. CARELLI
Coluna/Columna.2025;[Epub] CrossRef
Comparative Outcomes of Brachyury Vaccine vs. Imatinib in Advanced Chordoma: A Mayo Clinic Experience
Juan P. Navarro-Garcia de Llano, Harshvardhan G. Iyer, Harry C. Hoffman, Mahesh Seetharam, Steven Attia, Oluwaseun O. Akinduro
Cancers.2025; 17(21): 3493. CrossRef

11,368 View
171 Download
2 Web of Science
3 Crossref

Cervical Spine Chondroma Compressing Spinal Cord: A Case Report and Literature Review: Yoon Hwan Byun, Seil Sohn, Sung-Hye Park, Chun Kee Chung; Korean J Spine 2015;12(4):275-278. Published online December 31, 2015; DOI: https://doi.org/10.14245/kjs.2015.12.4.275

Abstract
PDF
Cite this article

Cite this article

export

Copy Download

Format

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
BibTeX — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

Cervical Spine Chondroma Compressing Spinal Cord: A Case Report and Literature Review

Korean J Spine. 2015;12(4):275-278. Published online December 31, 2015

DOI: https://doi.org/10.14245/kjs.2015.12.4.275

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
bib — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

Cervical Spine Chondroma Compressing Spinal Cord: A Case Report and Literature Review

Korean J Spine. 2015;12(4):275-278. Published online December 31, 2015

DOI: https://doi.org/10.14245/kjs.2015.12.4.275

Close

Chondromas are benign tumor of cartilaginous tissue that is rarely found in spine. The authors document a rare case of a 72 year old male patient with a cervical spinal chondroma compressing the spinal cord. The patient had symptoms of motor and sensory deficits, dysphagia and dysarthria. C1 and C2 laminotomy was done and the spinal tumor was removed. The patient gradually recovered from his previous symptom after the surgery.

Citations

Citations to this article as recorded by

En Bloc Resection of Malignant Cervical Spine Tumors With Consideration of Vertebral Artery Involvement
Rosa M. Egea-Gámez, Jaime García-Fernández, María Galán-Olleros, Alfonso González- Menocal, Ana M. Morales-Codina, Antonio Martín-Belloch, Rafael González-Díaz
Clinical Spine Surgery.2025;[Epub] CrossRef
Chondroma of the cervicothoracic intervertebral foramen: A case report and literature review
Lin Xiao, Wansheng Lin, Wei Zhang, Fei Wang
Asian Journal of Surgery.2023; 46(8): 3096. CrossRef
Chondromas of the Lumbar Spine: A Systematic Review
Luis A. Robles, Greg M. Mundis
Global Spine Journal.2021; 11(2): 232. CrossRef
Extradural Chondroma on the Lumbar Spine: A Case Report
Yong Guk Kim, Tae Wan Kim, Eun Ju Kim, Kwan Ho Park
The Nerve.2020; 6(2): 86. CrossRef
A Rare Case of Acute-Onset Spastic Quadriparesis Caused by a Chondroma of the Cervical Spine
Kaori Momota, Toshihiko Nishisho, Ryo Miyagi, Shunichi Toki, Kazuta Yamashita, Fumitake Tezuka, Yoichiro Takata, Toshinori Sakai, Akihiro Nagamachi, Toru Maeda, Koichi Sairyo
Case Reports in Orthopedics.2019; 2019: 1. CrossRef
Oropharyngeal Dysphagia Evaluation Tools in Adults with Solid Malignancies Outside the Head and Neck and Upper GI Tract: A Systematic Review
Ciarán Kenny, Órla Gilheaney, Declan Walsh, Julie Regan
Dysphagia.2018; 33(3): 303. CrossRef
Retro-odontoid mass without atlantoaxial instability causing cervical myelopathy: a case report of transdural surgical resection
Hiroyuki Tominaga, Takao Setoguchi, Satoshi Nagano, Ichiro Kawamura, Masahiko Abematsu, Takuya Yamamoto, Yasuhiro Ishidou, Kanehiro Matsuyama, Kosei Ijiri, Fumito Tanabe, Setsuro Komiya
Spinal Cord Series and Cases.2016;[Epub] CrossRef

10,325 View
112 Download
7 Crossref

Long-term Sequela of Intradural Extramedullary Tuberculoma in the Thoracic Dorsal Spinal Cord: Case Report and Review of the Literature: Seil Sohn, Yong Jun Jin, Ki-Jeong Kim, Hyun-Jib Kim; Korean J Spine 2011;8(4):295-299. Published online December 31, 2011; DOI: https://doi.org/10.14245/kjs.2011.8.4.295

Abstract
PDF
Cite this article

Cite this article

export

Copy Download

Format

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
BibTeX — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

Long-term Sequela of Intradural Extramedullary Tuberculoma in the Thoracic Dorsal Spinal Cord: Case Report and Review of the Literature

Korean J Spine. 2011;8(4):295-299. Published online December 31, 2011

DOI: https://doi.org/10.14245/kjs.2011.8.4.295

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
bib — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

Long-term Sequela of Intradural Extramedullary Tuberculoma in the Thoracic Dorsal Spinal Cord: Case Report and Review of the Literature

Korean J Spine. 2011;8(4):295-299. Published online December 31, 2011

DOI: https://doi.org/10.14245/kjs.2011.8.4.295

Close

A 45-year old man, who had tuberculosis five years ago presented with paresthesia, decreased proprioception, and gait disturbance in the lower extremity which were aggravated for a month. Magnetic resonance imaging revealed the T3-7 intradural extramedullary fibrotic mass with dark signal intensity on T2-weighted images. The yellowish material in the thick fibrous mass was confirmed as caseous necrosis. Two days after the operation, the symptoms improved. Although quite rare, intradural extramedullary tuberculoma should be considered as a chronic sequel of the previous medical history of pulmonary tuberculosis or tuberculous meningitis.

Citations

Citations to this article as recorded by

Intradural extramedullary tuberculoma in a case of disseminated tuberculosis: A case report
Chitranshu Shrivastava, Tushar Narayan Rathod, Rushikesh Bhanudas Shahade, Akshay Vasant Mohite, Bhushan Sunil Hadole, Deepika Jain
Surgical Neurology International.2024; 15: 477. CrossRef
Tubercular longitudinally extensive transverse myelitis (LETM): An enigma for primary care physicians
Kumar Abhishek Anand, Kalyan Kumar Bhowmik, Amit Sarkar, Ritwik Ghosh, Arpan Mandal, Bikash Swaika, Biman Kanti Ray
Journal of Family Medicine and Primary Care.2021; 10(2): 1057. CrossRef
Intradural extramedullary tuberculoma of the spinal cord in patient of tubercular meningitis - an uncommon scenario
Harleen Kaur, Gaurav Kumar Mittal, Jennifer Singhdev
Indian Journal of Tuberculosis.2020; 67(3): 426. CrossRef
Intradural extramedullary tuberculoma masquerading en plaque meningioma
Manchikanti Venkatesh, Pentyala Suneetha, Veldurti Kumar, Vissa Santhi, Luis Moscote-Salazar, Amit Agrawal
Asian Journal of Neurosurgery.2018; 13(03): 928. CrossRef
Experiences and Conceptualisation of Spinal Intramedullary Tuberculoma Management
Manish Jaiswal, Ashok Gandhi, Achal Sharma, Radhey Shyam Mittal
Korean Journal of Spine.2015; 12(1): 5. CrossRef
Intradural Extramedullary Tuberculoma of the Spinal Cord Following Tuberculous Meningitis
Deok-Ki Jeong, Young-Min Kwon
Korean Journal of Spine.2015; 12(2): 107. CrossRef