Skip to main navigation Skip to main content
  • E-Submission
  • Contact us

NS : Neurospine

OPEN ACCESS
Search
Advanced Search
ABOUT
BROWSE ARTICLES
FOR CONTRIBUTORS

Page Path

14
results for

"Sung Uk Kuh"

Article category

Publication year

More +

Keywords

More +

Authors

More +

Funded articles

More +

"Sung Uk Kuh"

Original Articles

Clinical Study – Cervical Spine

Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion
Jun Jae Shin, Sun Joon Yoo, Se Jun Park, Dong Kyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Chang Kyu Lee, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Joongkyum Shin, Yoon Ha
Neurospine 2025;22(4):937-948.   Published online December 31, 2025
DOI: https://doi.org/10.14245/ns.2551108.554

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion
Neurospine. 2025;22(4):937-948.   Published online December 31, 2025
DOI: https://doi.org/10.14245/ns.2551108.554
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion
Neurospine. 2025;22(4):937-948.   Published online December 31, 2025
DOI: https://doi.org/10.14245/ns.2551108.554
Close
Objective
To evaluate the clinical significance of a negative K-line in the neck flexion position (FK-line [-]), which indicates that cervical ossification of the posterior longitudinal ligament (OPLL) crosses the K-line during flexion, and to compare surgical outcomes between laminoplasty (LP) and laminectomy with fusion (LF) for multilevel FK-line (-) cervical OPLL.
Methods
A total of 349 patients with multiple cervical OPLL who underwent posterior decompression surgery (LP or LF) with a minimum of 2 years of follow-up were stratified by FK-line status. Clinical and radiological parameters were compared between the FK-line (+) and FK-line (-) groups. Subgroup analysis of FK-line (-) patients evaluated the efficacy of LP versus LF. Multivariate regression identified predictors of neurological recovery.
Results
Patients with FK-line (-) OPLL exhibited a smaller FK-line distance, more kyphotic alignment, greater cervical flexion, and lower recovery ratios compared to those with FK-line (+). In the FK-line (-) subgroup, LF achieved a significantly greater increase in FK-line distance, better correction of the flexion angle, and more neurological recovery than LP. Multivariate analyses identified postoperative FK-line distance, C2–7 flexion angle, and preoperative dynamic extension reserve as independent predictors of neurological outcomes.
Conclusion
FK-line status reflects the sagittal cord position and predicts surgical outcomes in cervical OPLL. In FK-line (-) patients, LF provides better neurological recovery and more effective posterior cord shift and kyphotic alignment correction than LP. Incorporating FK-line assessment to guide surgical planning could improve individualized treatment outcomes for multilevel OPLL.

Citations

Citations to this article as recorded by  Crossref logo
  • A Commentary on “Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion”
    John H. Chi
    Neurospine.2025; 22(4): 951.     CrossRef
  • A Commentary on “Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion”
    Yutaro Kanda
    Neurospine.2025; 22(4): 949.     CrossRef
  • From the Editor-in-Chief: Featured Articles in the December 2025 Issue
    Inbo Han
    Neurospine.2025; 22(4): 877.     CrossRef
  • 1,284 View
  • 73 Download
  • 3 Web of Science
  • 3 Crossref

Cervical Spine

The Role of K-Line and Canal-Occupying Ratio in Surgical Outcomes for Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Retrospective Multicenter Study
Jun Jae Shin, Sun Joon Yoo, Dong Kyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Won Joo Jeong, Tae Woo Kim, Chang Kyu Lee, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Joongkyum Shin, Yoon Ha
Neurospine 2025;22(2):337-348.   Published online June 30, 2025
DOI: https://doi.org/10.14245/ns.2550184.092

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

The Role of K-Line and Canal-Occupying Ratio in Surgical Outcomes for Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Retrospective Multicenter Study
Neurospine. 2025;22(2):337-348.   Published online June 30, 2025
DOI: https://doi.org/10.14245/ns.2550184.092
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
The Role of K-Line and Canal-Occupying Ratio in Surgical Outcomes for Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Retrospective Multicenter Study
Neurospine. 2025;22(2):337-348.   Published online June 30, 2025
DOI: https://doi.org/10.14245/ns.2550184.092
Close
Objective
To evaluate the impact of the K-line and canal-occupying ratio (COR) on surgical outcomes in patients with multilevel cervical ossification of the posterior longitudinal ligament (OPLL).
Methods
Patients with cervical myelopathy due to multilevel OPLL who underwent decompression surgery (anterior or posterior) from 2013 to 2022, with 2-year minimum follow-up, were enrolled. Radiological evaluations included K-line, COR, OPLL type/level, and cervical parameters (C2 slope [C2S], T1 slope [T1S], K-line tilt). Clinical outcomes included Japanese Orthopaedic Association (JOA) score and neck-pain visual analogue scale. Patients were categorized by K-line status (+/-) and COR (<50% or ≥50%).
Results
Among 575 patients, JOA recovery was significantly better in the K-line (+) and in low COR (<50%). In high COR (≥50%), K-line (-) was associated with poorer recovery. In low COR, outcomes were similar regardless of K-line. Anterior decompression with fusion (ADF) yielded the best outcomes. Laminoplasty (LP) was optimal for COR ≥50% and/or K-line (+), while laminectomy with fusion (LF) was better for COR ≥50% and K-line (-). In high COR, K-line was influenced by cervical alignment, C2S, and T1S, while in low COR, it was mainly affected by COR percentage.
Conclusion
Combining K-line and COR is essential for surgical planning in multilevel OPLL. When COR is high, K-line plays a significant role in predicting neurological recovery. ADF led to superior recovery, whereas for patients with K-line (-) and high COR, LF offered better results than LP. Cervical parameters at high COR influence the K-line more.

Citations

Citations to this article as recorded by  Crossref logo
  • Evaluating the demographics and complications of North American surgical patients with ossification of the posterior longitudinal ligament
    Aaron Phung, Justin Hyde, Justin Azmoodeh, Theodore Quan, Lancelot Benn, Christopher P. Bellaire, Oliver Tannous, Joseph Ferguson, Seyed B Kalantar, David Weiner, Andrew Mo, Fred Mo, Sean Bae, Ala Alshomali, Crisanto L. Macaraeg, Kevin Yoon, Jonathan P. J
    Journal of Clinical Neuroscience.2026; 144: 111790.     CrossRef
  • Radiological assessment in cervical spine myelopathy
    Shanmuganathan Rajasekaran, Gnanaprakash Gurusamy, Pushpa Bhari Thippeswamy, Karthik Ramachandran, Stefano Conti
    Journal of Clinical Orthopaedics and Trauma.2026; 72: 103301.     CrossRef
  • C2-Involving Cervical Ossification of the Posterior Longitudinal Ligament (OPLL): Dome-like Laminoplasty Versus Laminectomy With Fusion
    Jun Jae Shin, Sun Joon Yoo, Se Jun Park, Dong Kyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Joongkyum Shin, Yoon Ha
    Global Spine Journal.2026;[Epub]     CrossRef
  • Dynamic K-Line Status and Surgical Outcomes in Multilevel Cervical OPLL: A Multicenter Comparative Study
    Jun Jae Shin, Sun Joon Yoo, Se Jun Park, Dong Kyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Chang Kyu Lee, Keung Nyun Kim, Tae Woo Kim, Yoon Ha
    Journal of Clinical Medicine.2026; 15(2): 520.     CrossRef
  • A comparative study on surgical management of long-course symptomatic cervical OPLL between anterior en bloc resection and posterior laminectomy with instrumented fusion
    Kefu Chen, Yiwei Lu, Shu Liu, Lianshun Jia, Xingcheng Dong, Tianwen Ye
    BMC Musculoskeletal Disorders.2026;[Epub]     CrossRef
  • Reduction of Spinal Cord Cross-Sectional Area Is Associated With Myelopathy in Severe Cervical Ossification of the Posterior Longitudinal Ligaments
    Hyun-Jun Jang, Dong-Kyu Kim, Bong-Ju Moon, Kyung-Hyun Kim, Jeong-Yoon Park, Sung-Uk Kuh, Keun-Su Kim, Yong-Eun Cho, Dong-Kyu Chin
    Neurosurgery.2026;[Epub]     CrossRef
  • Spinal cord extracellular matrix hydrogel enhances organoid maturation and functional regeneration after spinal cord injury
    Junghoon Kim, Songzi Zhang, Joon-Hyuk Jung, Mi-Jeong Lee, Inbo Han, Seung-Woo Cho
    Materials Today Bio.2026; 38: 103168.     CrossRef
  • Surgical Technique and Technical Pearls of O-arm Navigation-assisted Anterior Cervical Corpectomy and Fusion for Cervical Ossification of the Posterior Longitudinal Ligament (OPLL)
    Yusuke Nishimura
    Spinal Surgery.2026; 40(1): 8.     CrossRef
  • Flexion K-Line Status Predicts Surgical Strategy in Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Multicenter Comparison of Laminoplasty and Laminectomy With Fusion
    Jun Jae Shin, Sun Joon Yoo, Se Jun Park, Dong Kyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Chang Kyu Lee, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Joongkyum Shin, Yoon Ha
    Neurospine.2025; 22(4): 937.     CrossRef
  • 8,894 View
  • 249 Download
  • 9 Web of Science
  • 9 Crossref

Deformity

Application of Transverse Process Hooks at Distal Thoracic Vertebrae in Uppermost Vertebral Instrumentation for Adult Spinal Deformity Surgery: Special Focus on Delayed-Onset Neurologic Deficits
Sun-Joon Yoo, Hyun-Jun Jang, Bong Ju Moon, Jeong-Yoon Park, Sung Uk Kuh, Dong-Kyu Chin, Keun-Su Kim, Jun Jae Shin, Yoon Ha, Kyung-Hyun Kim
Neurospine 2024;21(4):1219-1229.   Published online December 31, 2024
DOI: https://doi.org/10.14245/ns.2448804.402

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Application of Transverse Process Hooks at Distal Thoracic Vertebrae in Uppermost Vertebral Instrumentation for Adult Spinal Deformity Surgery: Special Focus on Delayed-Onset Neurologic Deficits
Neurospine. 2024;21(4):1219-1229.   Published online December 31, 2024
DOI: https://doi.org/10.14245/ns.2448804.402
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Application of Transverse Process Hooks at Distal Thoracic Vertebrae in Uppermost Vertebral Instrumentation for Adult Spinal Deformity Surgery: Special Focus on Delayed-Onset Neurologic Deficits
Neurospine. 2024;21(4):1219-1229.   Published online December 31, 2024
DOI: https://doi.org/10.14245/ns.2448804.402
Close
Objective
We aimed to investigate the incidence of delayed-onset neurological deficits (DONDs), DOND-related reoperation rates following adult spinal deformity (ASD) surgery, and efficacy of transverse process hooks (TPHs) at the uppermost instrumented vertebra (UIV) compared to pedicle screws (PSs).
Methods
We included 90 consecutive patients who underwent instrumented fusion from the sacrum to the distal thoracic spine for ASD, with a minimum follow-up of 24 months. Clinical and radiological outcomes were compared between 33 patients in the TPH group and 57 patients in the PS group, using the Scoliosis Research Society-22 Outcomes questionnaire (SRS-22), Medical Outcomes Study Questionnaire Short-Form 36 (SF-36), and various spinal sagittal parameters.
Results
While absent in the TPH group, myelopathy occurred in 15.8% of the PS group, wherein 15 patients underwent reoperation. The change in the proximal junctional angle, from the pre- to postoperative assessment, was lower in the TPH group than in the PS group (0.2 vs. 6.6, p=0.002). Postoperative facet degeneration in the PS group progressed more significantly than in the TPH group (0.5 vs. 0.1, p=0.002). Surgical outcomes were comparable for both groups, except for the back visual analogue scale (3.5 vs. 4.1, p=0.010) and SRS-22 domains, including pain and satisfaction (3.3 vs. 2.9, p=0.033; 3.7 vs. 3.3, p=0.041). No intergroup difference was observed in SF-36.
Conclusion
Using TPHs at the UIV level can prevent DOND, and thereby prevent postoperative myelopathy that necessitates reoperation; thus, TPHs is preferable over PSs in ASD surgery.

Citations

Citations to this article as recorded by  Crossref logo
  • Clinical and radiological outcomes of transverse process hooks versus pedicle screws at the upper instrumented vertebra in adult spinal deformity patients undergoing three-column osteotomy: A retrospective comparative study
    Mohsen Rostami, Sadegh Bagherzadeh, Navid Moghadam, Faramarz Roohollahi, Cesar Carballo Cuello, Jay Kumar, Mark Greenberg, Puya Alikhani
    Clinical Neurology and Neurosurgery.2026; 261: 109263.     CrossRef
  • Comparison of Hook Fixation and Vertebroplasty for Prevention of Proximal Junctional Failure: A Retrospective Cohort Study
    Sung Tan Cho, Jae Hwan Cho, Dong-Ho Lee, Chang Ju Hwang, Sehan Park, Jin Hwan Kim, Wongthawat Liawrungrueang
    Global Spine Journal.2026;[Epub]     CrossRef
  • Prevalence and Risk Factors for Postoperative Neurological Complications in Spinal Deformity Surgery: A Systematic Review and Proportional Meta-Analysis
    Yam Wa Man, Jedidiah Yui Shing Lui, Chor Yin Lam, Jason Pui Yin Cheung, Prudence Wing Hang Cheung
    Neurospine.2025; 22(1): 243.     CrossRef
  • 3,909 View
  • 128 Download
  • 3 Web of Science
  • 3 Crossref
Comparison of the Clinical Efficacy of Anabolic Agents and Bisphosphonates in the Patients With Osteoporotic Vertebral Fracture: Systematic Review and Meta-analysis of Randomized Controlled Trials
Ikchan Jeon, Sung Bae Park, Bong Ju Moon, Miyoung Choi, Sung Uk Kuh, Jongtae Kim
Neurospine 2024;21(2):416-429.   Published online May 2, 2024
DOI: https://doi.org/10.14245/ns.2347256.628

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Comparison of the Clinical Efficacy of Anabolic Agents and Bisphosphonates in the Patients With Osteoporotic Vertebral Fracture: Systematic Review and Meta-analysis of Randomized Controlled Trials
Neurospine. 2024;21(2):416-429.   Published online May 2, 2024
DOI: https://doi.org/10.14245/ns.2347256.628
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Comparison of the Clinical Efficacy of Anabolic Agents and Bisphosphonates in the Patients With Osteoporotic Vertebral Fracture: Systematic Review and Meta-analysis of Randomized Controlled Trials
Neurospine. 2024;21(2):416-429.   Published online May 2, 2024
DOI: https://doi.org/10.14245/ns.2347256.628
Close
Objective
We investigated the clinical efficacy of anabolic agents compared with bisphosphonates (BPs) for the incidence of new osteoporotic vertebral fracture (OVF) and fracture healing of OVF in the patients with OVF via meta-analyses of randomized controlled trials (RCTs).
Methods
Electronic databases, including PubMed, Embase, and Cochrane Library were searched for published RCTs till December 2022. The RCTs that recruited participants with osteoporosis at high-/very high-risk of fracture (a history of osteoporotic vertebral or hip fracture) or fresh OVF were included in this study. We assessed the risk of bias on every included RCTs, estimated relative risk (RR) for the incidence of new OVF and fracture healing of OVF, and overall certainty of evidence. Meta-analyses were performed by Cochrane review manager (RevMan) ver. 5.3. Cochrane risk of bias 2.0 and GRADEpro/GDT were applied for evaluating methodological quality and overall certainty of evidence, respectively.
Results
Five hundred eighteen studies were screened, and finally 6 eligible RCTs were included in the analysis. In the patients with prevalent OVF, anabolic agents significantly reduced the incidence of new OVF (teriparatide and romosozumab vs. alendronate and risedronate [RR, 0.57; 95% confidence interval, 0.45–0.71; p < 0.00001; high-certainty of evidence]; teriparatide vs. risedronate [RR, 0.50; 95% confidence interval, 0.37–0.68; p < 0.0001; high-certainty of evidence]). However, there was no evidence of teriparatide compared to alendronate in fracture healing of OVF (RR, 1.23; 95% confidence interval, 0.95–1.60; p = 0.12; low-certainty of evidence).
Conclusion
In the patients with prevalent OVF, anabolic agents showed a significant superiority for preventing new OVF than BPs, with no significant evidence for promoting fracture healing of OVF. However, considering small number of RCTs in this study, additional studies with large-scale data are required to obtain more robust evidences.

Citations

Citations to this article as recorded by  Crossref logo
  • Development of an explainable machine learning model to reproduce and interpret expert pharmacological decisions in osteoporosis treatment
    Yutaro Sugawara, Tomohiro Shimizu, Hotaka Ishizu, Kosuke Arita, Yusuke Ohashi, Shu Yamazaki, Terufumi Kokabu, Katsuhisa Yamada, Norimasa Iwasaki
    Bone.2026; 204: 117745.     CrossRef
  • Disuse Bone Loss in Fusion Constructs After Multilevel Lumbar Fusion: A Computed Tomography Hounsfield Unit Analysis
    Hyun-Jun Jang, Dongkyu Kim, Bong-Ju Moon, Kyung-Hyun Kim, Jeong-Yoon Park, Sung-Uk Kuh, Keun-Su Kim, Dong-Kyu Chin
    Neurospine.2026; 23(1): 176.     CrossRef
  • Under-prescribed and underutilized: National trends in osteoporosis medication use after fragility fracture
    Harsh Wadhwa, Katelin J. Isakoff, Nicole S. Pham, L. Henry Goodnough, Julius A. Bishop, Michael J. Gardner
    Bone.2026; 206: 117835.     CrossRef
  • Comparative Radiologic Outcomes of Romosozumab and Teriparatide in Osteoporotic Vertebral Fractures
    Jun-Seok Lee, Geon-U Kim, Ho-Young Jung, Young-Hoon Kim, Sang-Il Kim, Sangjun Park, Young-Yul Kim, Hyung-Youl Park
    Journal of Clinical Medicine.2026; 15(6): 2349.     CrossRef
  • A Comparison Between Bisphosphonates and Teriparatide in the Treatment of Postmenopausal Osteoporosis: A Systematic Review
    Russaal S Mann, Isha Chopra, Abdullah Kilic, Ayushi Saxena, Bilal Khan, Rupanshu Rupanshu, Paolo S Chavez Cavalie
    Cureus.2026;[Epub]     CrossRef
  • Sequential Versus Step-Therapy Approaches for Osteoporosis Management in Orthopedic Subspecialties
    Samer G. Salman, Rohan Phadke, James Burnett, Jonathan Walsh
    Current Osteoporosis Reports.2026;[Epub]     CrossRef
  • Effectiveness of Posterior Long-Segment Fixation for Thoracolumbar Osteoporotic Compression Fractures: A Retrospective Study
    Jong-Hwan Hong, Jong-Hoon Jung, Ji-Ho Jung, Moon-Soo Han, Jung-Kil Lee
    World Neurosurgery.2025; 194: 123433.     CrossRef
  • A Real-Life Study in Sequential Therapy for Severe Menopausal Osteoporosis
    Oana-Claudia Sima, Mihai Costachescu, Mihaela Stanciu, Claudiu Nistor, Mara Carsote, Denisa Tanasescu, Florina Ligia Popa, Ana Valea
    Journal of Clinical Medicine.2025; 14(2): 627.     CrossRef
  • Comparative Analysis of Romosozumab Versus Vertebroplasty With Denosumab: Efficacy, Safety, and Secondary Bone Mineral Density Outcomes
    Hyun Woong Mun, Jong Joo Lee, Hyun Chul Shin, Tae-Hwan Kim, Seok Woo Kim, Jae Keun Oh
    Neurospine.2025; 22(1): 69.     CrossRef
  • A Commentary on “Comparative Analysis of Romosozumab Versus Vertebroplasty With Denosumab: Efficacy, Safety, and Secondary Bone Mineral Density Outcomes”
    Toshihiko Inui
    Neurospine.2025; 22(1): 78.     CrossRef
  • Clinical Outcomes and Risk Factors Associated with Spinal Kyphotic Deformity Following Osteoporotic Vertebral Fracture
    Hayato Oishi, Keishi Maruo, Tomoyuki Kusukawa, Tetsuto Yamaura, Kazuma Nagao, Masakazu Toi, Masaru Hatano, Fumihiro Arizumi, Norichika Yoshie, Toshiya Tachibana
    Journal of Clinical Medicine.2025; 14(8): 2769.     CrossRef
  • Revisiting Cement Augmentation in Osteoporotic Vertebral Fractures: A Narrative Review
    Gilbert Bungay Dimacali, Byung Ho Lee
    Journal of Korean Society of Spine Surgery.2025; 32(4): 144.     CrossRef
  • The Effects of Longer Use of Teriparatide on Clinical and Radiographic Outcomes after Spinal Fusion in Geriatric Patients
    Young-Hoon Kim, Kee-Yong Ha, Hyun W. Bae, Hyung-Youl Park, Young-Il Ko, Myung-Sup Ko, Sang-Il Kim
    Medicina.2024; 60(6): 946.     CrossRef
  • From the Editor-in-Chief: Featured Articles in the June 2024 Issue
    Inbo Han
    Neurospine.2024; 21(2): 373.     CrossRef
  • Commentary on “Comparison of the Clinical Efficacy of Anabolic Agents and Bisphosphonates in the Patients With Osteoporotic Vertebral Fracture: Systematic Review and Meta-analysis of Randomized Controlled Trials”
    Dae-Chul Cho
    Neurospine.2024; 21(2): 430.     CrossRef
  • 16,012 View
  • 359 Download
  • 13 Web of Science
  • 15 Crossref
Three-Dimensional Quantitative Assessment of Pedicle Screw Accuracy in Clinical Utilization of a New Robotic System in Spine Surgery: A Multicenter Study
Byeong-Jin Ha, Jong-Min Lee, Seon-Jin Yoon, Byung-Kwan Kim, Junseok Lee, Suhun Lee, Seungjae Ryu, Yongyeob Cha, Sungteac Hwang, Donggi Woo, Chang Kyu Lee, Dong Ah Shin, Yoon Ha, Sung Uk Kuh, Keung Nyun Kim, Dongwuk Son, Seong Yi
Neurospine 2023;20(3):1028-1039.   Published online September 30, 2023
DOI: https://doi.org/10.14245/ns.2346552.276

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Three-Dimensional Quantitative Assessment of Pedicle Screw Accuracy in Clinical Utilization of a New Robotic System in Spine Surgery: A Multicenter Study
Neurospine. 2023;20(3):1028-1039.   Published online September 30, 2023
DOI: https://doi.org/10.14245/ns.2346552.276
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Three-Dimensional Quantitative Assessment of Pedicle Screw Accuracy in Clinical Utilization of a New Robotic System in Spine Surgery: A Multicenter Study
Neurospine. 2023;20(3):1028-1039.   Published online September 30, 2023
DOI: https://doi.org/10.14245/ns.2346552.276
Close
Objective
The objective of this study was to evaluate the accuracy of pedicle screw placement in patients undergoing percutaneous pedicle screw fixation with robotic guidance, using a newly developed 3-dimensional quantitative measurement system. The study also aimed to assess the clinical feasibility of the robotic system in the field of spinal surgery.
Methods
A total of 113 patients underwent pedicle screw insertion using the CUVIS-spine pedicle screw guide system (CUREXO Inc.). Intraoperative O-arm images were obtained, and screw insertion pathways were planned accordingly. Image registration was performed using paired-point registration and iterative closest point methods. The accuracy of the robotic-guided pedicle screw insertion was assessed using 3-dimensional offset calculation and the Gertzbein-Robbins system (GRS).
Results
A total of 448 screws were inserted in the 113 patients. The image registration success rate was 95.16%. The average error of entry offset was 2.86 mm, target offset was 2.48 mm, depth offset was 1.99 mm, and angular offset was 3.07°. According to the GRS grading system, 88.39% of the screws were classified as grade A, 9.60% as grade B, 1.56% as grade C, 0.22% as grade D, and 0.22% as grade E. Clinically acceptable screws (GRS grade A or B) accounted for 97.54% of the total, with no reported neurologic complications.
Conclusion
Our study demonstrated that pedicle screw insertion using the novel robot-assisted navigation method is both accurate and safe. Further prospective studies are necessary to explore the potential benefits of this robot-assisted technique in comparison to conventional approaches.

Citations

Citations to this article as recorded by  Crossref logo
  • Evaluation of pedicle screw accuracy and deviation from preoperative planning in intraoperative Cone-Beam Computed Tomography-Navigated lumbar spinal fusion: a prospective study
    Gianluca Vadalà, Giuseppe Francesco Papalia, Niccolò Nardi, Fabrizio Russo, Luca Ambrosio, Girolamo Maltese, Rocco Papalia, Vincenzo Denaro
    Brain and Spine.2026; 6: 105988.     CrossRef
  • Combining Engineering Precision with Clinical Relevance: A Novel Dual Framework for Assessing Pedicle Screw Accuracy in Spine Surgery
    Arnaud Delafontaine, Olivier Cartiaux, Bernard G. Francq, Virginie Cordemans
    Journal of Clinical Medicine.2026; 15(6): 2328.     CrossRef
  • Robotic Spine Surgery: Systematic Review of Common Error Types and Best Practices
    Diwas Gautam, Sheela Vivekanandan, Marcus D. Mazur
    Operative Neurosurgery.2025; 28(3): 295.     CrossRef
  • Advancements in robotic-assisted spine surgery: A literature review and technology comparison
    Jonathan Hammond, Stefano Priola
    Interdisciplinary Neurosurgery.2025; 40: 102056.     CrossRef
  • Robotic-Guided Spine Surgery: Implementation of a System in Routine Clinical Practice—An Update
    Mirza Pojskić, Miriam Bopp, Omar Alwakaa, Christopher Nimsky, Benjamin Saß
    Journal of Clinical Medicine.2025; 14(13): 4463.     CrossRef
  • Evaluating accuracy in robotic-assisted thoracolumbar pedicle screw placement: Insights from a single-center study of 410 patients
    Abhishek Soni, Vidyadhara Srinivasa, Akhil Xavier Joseph, Balamurugan Thirugnanam, Alia Vidyadhara
    Journal of Craniovertebral Junction and Spine.2025; 16(4): 408.     CrossRef
  • Robotic-Assisted Spine Surgery: Role in Training the Next Generation of Spine Surgeons
    Jun Seok Lee, Dong Wuk Son, Su Hun Lee, Jong Hyeok Lee, Young Ha Kim, Sang Weon Lee, Bu Kwang Oh, Soon Ki Sung, Geun Sung Song, Seong Yi
    Neurospine.2024; 21(1): 116.     CrossRef
  • Artificial Intelligence (AI)-Robotics Started When Human Capability Reached Limit, Human Creativity Begin Again When the Capability of AI-Robotics Reaches a Plateau
    Seong Yi
    Neurospine.2024; 21(1): 3.     CrossRef
  • Navigation-Guided/Robot-Assisted Spinal Surgery: A Review Article
    Young-Seok Lee, Dae-Chul Cho, Kyoung-Tae Kim
    Neurospine.2024; 21(1): 8.     CrossRef
  • Fully automated determination of robotic pedicle screw accuracy and precision utilizing computer vision algorithms
    Benjamin N. Groisser, Ankush Thakur, Howard J. Hillstrom, Akshitha Adhiyaman, Colson Zucker, Jerry Du, Matthew Cunningham, M. Timothy Hresko, Ram Haddas, John Blanco, Hollis G. Potter, Douglas N. Mintz, Ryan E. Breighner, Jessica H. Heyer, Roger F. Widman
    Journal of Robotic Surgery.2024;[Epub]     CrossRef
  • 9,991 View
  • 229 Download
  • 12 Web of Science
  • 10 Crossref
Predicting Mechanical Complications After Adult Spinal Deformity Operation Using a Machine Learning Based on Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density
Sung Hyun Noh, Hye Sun Lee, Go Eun Park, Yoon Ha, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Sang Hyun Kim, Kyung Hyun Kim
Neurospine 2023;20(1):265-274.   Published online March 31, 2023
DOI: https://doi.org/10.14245/ns.2244854.427

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Predicting Mechanical Complications After Adult Spinal Deformity Operation Using a Machine Learning Based on Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density
Neurospine. 2023;20(1):265-274.   Published online March 31, 2023
DOI: https://doi.org/10.14245/ns.2244854.427
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Predicting Mechanical Complications After Adult Spinal Deformity Operation Using a Machine Learning Based on Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density
Neurospine. 2023;20(1):265-274.   Published online March 31, 2023
DOI: https://doi.org/10.14245/ns.2244854.427
Close
Objective
This study aimed to create an ideal machine learning model to predict mechanical complications in adult spinal deformity (ASD) surgery based on GAPB (modified global alignment and proportion scoring with body mass index and bone mineral density) factors.
Methods
Between January 2009 and December 2018, 238 consecutive patients with ASD, who received at least 4-level fusions and were followed-up for ≥ 2 years, were included in the study. The data were stratified into training (n = 167, 70%) and test (n = 71, 30%) sets and input to machine learning algorithms, including logistic regression, random forest gradient boosting system, and deep neural network.
Results
Body mass index, bone mineral density, the relative pelvic version score, the relative lumbar lordosis score, and the relative sagittal alignment score of the global alignment and proportion score were significantly different in the training and test sets (p < 0.05) between the complication and no complication groups. In the training set, the area under receiver operating characteristics (AUROCs) for logistic regression, gradient boosting, random forest, and deep neural network were 0.871 (0.817–0.925), 0.942 (0.911–0.974), 1.000 (1.000–1.000), and 0.947 (0.915–0.980), respectively, and the accuracies were 0.784 (0.722–0.847), 0.868 (0.817–0.920), 1.000 (1.000–1.000), and 0.856 (0.803–0.909), respectively. In the test set, the AUROCs were 0.785 (0.678–0.893), 0.808 (0.702–0.914), 0.810 (0.710–0.910), and 0.730 (0.610–0.850), respectively, and the accuracies were 0.732 (0.629–0.835), 0.718 (0.614–0.823), 0.732 (0.629–0.835), and 0.620 (0.507–0.733), respectively. The random forest achieved the best predictive performance on the training and test dataset.
Conclusion
This study created a comprehensive model to predict mechanical complications after ASD surgery. The best prediction accuracy was 73.2% for predicting mechanical complications after ASD surgery.

Citations

Citations to this article as recorded by  Crossref logo
  • Determining the risk factors for postoperative mechanical complication in degenerative scoliosis: a machine learning approach based on musculoskeletal metrics
    Jie Li, Zhen Tian, Yinyu Fang, Zhong He, Yanjie Xu, Hui Xu, Zezhang Zhu, Yong Qiu, Zhen Liu
    European Spine Journal.2026; 35(1): 156.     CrossRef
  • Development and validation of a deep learning–powered system for multi-version global alignment and proportion score to predict mechanical complications after adult degenerative scoliosis surgery
    Qifeng Lan, Shanshan Liu, Cheng Zhang, Chenyi Guo, Yiming Shi, Jian He, Xingyu Zhou, Jiaheng Shang, Qiang Qi, Zhaoqing Guo, Zhuoran Sun, Siyu Zhou, Ji Wu, Nanfang Xu, Weishi Li
    European Spine Journal.2026; 35(2): 375.     CrossRef
  • Proximal Junctional Kyphosis Prevention in Adult Spinal Deformity Surgery: A Technical Review of Tethering and Adjunctive Strategies
    Paritash Tahmasebpour, Pawel P. Jankowski, Jason Liang, Joshua Lin, Kyriakos D. Chatzis, Peter S. Tretiakov, Spencer Matthews, Louis Boissiere, John F. Burke, Christopher I. Shaffrey, Aaron Hockley, Peter Passias
    Operative Neurosurgery.2026;[Epub]     CrossRef
  • Predicting postoperative mechanical complications with the ethnicity-adjusted global alignment and proportion score in degenerative scoliosis: does paraspinal muscle degeneration matter?
    Peiyu Li, Jie Li, Abdukahar Kiram, Zhen Tian, Xing Sun, Xiaodong Qin, Benlong Shi, Yong Qiu, Zhen Liu, Zezhang Zhu
    The Spine Journal.2025; 25(2): 347.     CrossRef
  • Uso de inteligencia artificial para predecir complicaciones en cirugías de columna toracolumbar degenerativa: revisión sistemática
    G. Ricciardi, J.I. Cirillo Totera, R. Pons Belmonte, L. Romero Valverde, F. López Muñoz, A. Manríquez Díaz
    Revista Española de Cirugía Ortopédica y Traumatología.2025; 69(5): 446.     CrossRef
  • Risk Factors of 90-Day Unplanned Readmission After Lumbar Spine Surgery for Degenerative Lumbar Disk Disease: A Systematic Review and Meta-Analysis
    Jeong In Seol, Jeong Hoon Yoo, Hyeon Gyu Sung, Hyun Ho Park, Sung Hyeon Noh
    Neurosurgery.2025; 97(4): 908.     CrossRef
  • AI and machine learning in paediatric spine deformity surgery
    Mohsin Khan, Kaustubh Ahuja, Athanasios I Tsirikos
    Bone & Joint Open.2025; 6(5): 569.     CrossRef
  • Novel risk factors and personalized risk calculator for predicting proximal junctional kyphosis after adult spinal deformity surgery
    Qijun Wang, Zheng Wang, Dongfan Wang, Xuan Zhao, Xiaolong Chen, Shibao Lu
    The Bone & Joint Journal.2025; 107-B(8): 829.     CrossRef
  • [Translated article] Use of artificial intelligence to predict complications in degenerative thoracolumbar spine surgery: A systematic review
    G. Ricciardi, J.I. Cirillo Totera, R. Pons Belmonte, L. Romero Valverde, F. López Muñoz, A. Manríquez Díaz
    Revista Española de Cirugía Ortopédica y Traumatología.2025; 69(5): T446.     CrossRef
  • Applications of Artificial Intelligence in the Diagnosis and Treatment of Pediatric Congenital malformations: Recent Advances
    鑫 王
    Advances in Clinical Medicine.2025; 15(09): 91.     CrossRef
  • The predictive value of the global alignment and proportion (GAP) score for mechanical complications following adult spinal deformity surgery: A systematic review and meta-analysis
    Vinicius Ricieri Ferraz, Guilherme Santos Piedade, Carlos R. Goulart, Maria Fernanda Ricieri Ferraz Franco de Souza, Marcelo Ochoa Coelho de Souza Furlan, Philippe A. Mercier, Tobias A. Mattei
    North American Spine Society Journal (NASSJ).2025; 24: 100816.     CrossRef
  • Predicting proximal junctional failure in adult spinal deformity patients using machine learning models based on spinal alignment parameters
    Akihiko Hiyama, Daisuke Sakai, Hiroyuki Katoh, Masato Sato, Masahiko Watanabe
    Scientific Reports.2025;[Epub]     CrossRef
  • Evaluating Computer Vision, Large Language, and Genome-Wide Association Models in a Limited Sized Patient Cohort for Pre-Operative Risk Stratification in Adult Spinal Deformity Surgery
    Ethan Schonfeld, Aaradhya Pant, Aaryan Shah, Sina Sadeghzadeh, Dhiraj Pangal, Adrian Rodrigues, Kelly Yoo, Neelan Marianayagam, Ghani Haider, Anand Veeravagu
    Journal of Clinical Medicine.2024; 13(3): 656.     CrossRef
  • Lower Hounsfield Units at the Planned Lowest Instrumented Vertebra Is an Independent Risk Factor for Complications Following Adult Cervical Deformity Surgery
    Tyler K. Williamson, Ezekial J. Koslosky, Jordan Lebovic, Stephane Owusu-Sarpong, Peter Tretiakov, Jamshaid Mir, Pooja Dave, Andrew J. Schoenfeld, Bassel G. Diebo, Heiko Koller, Renaud Lafage, Virginie Lafage, Peter G. Passias
    Clinical Spine Surgery.2024; 37(10): E503.     CrossRef
  • Commentary on “Performance of a Large Language Model in the Generation of Clinical Guidelines for Antibiotic Prophylaxis in Spine Surgery”
    Sun-Ho Lee
    Neurospine.2024; 21(1): 147.     CrossRef
  • Deep Learning Method for Precise Landmark Identification and Structural Assessment of Whole-Spine Radiographs
    Sung Hyun Noh, Gaeun Lee, Hyun-Jin Bae, Ju Yeon Han, Su Jeong Son, Deok Kim, Jeong Yeon Park, Seung Kyeong Choi, Pyung Goo Cho, Sang Hyun Kim, Woon Tak Yuh, Su Hun Lee, Bumsoo Park, Kwang-Ryeol Kim, Kyoung-Tae Kim, Yoon Ha
    Bioengineering.2024; 11(5): 481.     CrossRef
  • Research of Global Tilt and Functional Independence: Insights into Spinal Health of Older Women
    Yu-Chieh Chiu, Ping-Chiao Tsai, Ssu-Hsien Lee, Wen-Tien Wu, Tzai-Chiu Yu, Ru-Ping Lee, Ing-Ho Chen, Jen-Hung Wang, Kuang-Ting Yeh
    Bioengineering.2024; 11(5): 493.     CrossRef
  • Trends in degenerative lumbar spinal surgery during the early COVID-19 pandemic in Republic of Korea: A national study utilizing the national health insurance database
    Woon Tak Yuh, Jinhee Kim, Mi-Sook Kim, Jun-Hoe Kim, Young Rak Kim, Sum Kim, Chun Kee Chung, Chang-Hyun Lee, Sung Bae Park, Kyoung-Tae Kim, John M. Rhee, Young San Ko, Chi Heon Kim, Kentaro Yamada
    PLOS ONE.2024; 19(6): e0305128.     CrossRef
  • Machine learning applications in adult spinal deformity corrective surgery: a narrative review
    Nader Toossi, Ozhan Jerry
    Artificial Intelligence Surgery.2024; 4(3): 258.     CrossRef
  • Prediction of postoperative mechanical complications in ASD patients based on total sequence and proportional score of spinal sagittal plane
    Wenbin Jiang, Huagang Shi, Tao Gu, Zonglin Cai, Qinglong Li
    SLAS Technology.2024; 29(6): 100222.     CrossRef
  • Classification of lumbar spine disorders using large language models and MRI segmentation
    Rongpeng Dong, Xueliang Cheng, Mingyang Kang, Yang Qu
    BMC Medical Informatics and Decision Making.2024;[Epub]     CrossRef
  • Proximal Junctional Failure Development Despite Achieving Ideal Sagittal Correction According to Age-Adjusted Alignment Target in Patients With Adult Spinal Deformity: Risk Factor Analysis of 196 Cases Undergoing Low Thoracic to Pelvic Fusion
    Se-Jun Park, Jin-Sung Park, Dong-Ho Kang, Minwook Kang, Kyunghun Jung, Chong-Suh Lee
    Neurospine.2024; 21(4): 1080.     CrossRef
  • Complication Rates and Utilization Trends of 3-Level Posterior Column Osteotomy Compared to Single-Level Pedicle Subtraction Osteotomy
    Emily S. Mills, Kevin Mertz, Ethan Faye, Jennifer A. Bell, Andy T. Ton, Jeffrey C. Wang, Ram K. Alluri, Raymond J. Hah
    Neurospine.2023; 20(2): 662.     CrossRef
  • Proximal Junctional Failure in Adult Spinal Deformity Surgery: An In-depth Review
    Mitsuru Yagi, Kento Yamanouchi, Naruhito Fujita, Haruki Funao, Shigeto Ebata
    Neurospine.2023; 20(3): 876.     CrossRef
  • Proximal Junctional Kyphosis or Failure After Adult Spinal Deformity Surgery - Review of Risk Factors and Its Prevention
    Byung-Jou Lee, Sung Soo Bae, Ho Young Choi, Jin Hoon Park, Seung-Jae Hyun, Dae Jean Jo, Yongjae Cho
    Neurospine.2023; 20(3): 863.     CrossRef
  • Development and Validation of an Online Calculator to Predict Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery Using Machine Learning
    Chang-Hyun Lee, Dae-Jean Jo, Jae Keun Oh, Seung-Jae Hyun, Jin Hoon Park, Kyung Hyun Kim, Jun Seok Bae, Bong Ju Moon, Chang-Kyu Lee, Myoung Hoon Shin, Hyun Jun Jang, Moon-Soo Han, Chi Heon Kim, Chun Kee Chung, Seung-Myung Moon
    Neurospine.2023; 20(4): 1272.     CrossRef
  • Commentary on “Development and Validation of an Online Calculator to Predict Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery Using Machine Learning”
    In Ho Han
    Neurospine.2023; 20(4): 1281.     CrossRef
  • 8,006 View
  • 253 Download
  • 25 Web of Science
  • 27 Crossref
Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density Analysis in Global Alignment and Proportion Score of Each 3 Categories for Predicting Mechanical Complications After Adult Spinal Deformity Surgery
Sung Hyun Noh, Yoon Ha, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Hye Sun Lee, Kyung Hyun Kim
Neurospine 2021;18(3):484-491.   Published online September 30, 2021
DOI: https://doi.org/10.14245/ns.2142470.235

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density Analysis in Global Alignment and Proportion Score of Each 3 Categories for Predicting Mechanical Complications After Adult Spinal Deformity Surgery
Neurospine. 2021;18(3):484-491.   Published online September 30, 2021
DOI: https://doi.org/10.14245/ns.2142470.235
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density Analysis in Global Alignment and Proportion Score of Each 3 Categories for Predicting Mechanical Complications After Adult Spinal Deformity Surgery
Neurospine. 2021;18(3):484-491.   Published online September 30, 2021
DOI: https://doi.org/10.14245/ns.2142470.235
Close
Objective
This study aimed to analyze the prediction rate of the modified Global Alignment and Proportion (GAP) scoring system with body mass index and bone mineral density (GAPB) in each GAP of the 3 categories.
Methods
Between January 2009 and December 2016, 203 consecutive patients with adult spinal deformity (ASD) underwent corrective fusion of more than 4 levels and were followedup for more than 2 years. As a validation of the GAPB, the GAPB was divided into tertiles (Q1, Q2, Q3) for each section of the GAP score. Each patient’s GAP score and GAPB system complication rate were examined.
Results
Of the 203 patients, 89 patients (44%) developed mechanical complications after ASD surgery. A GAP score analysis of the patients found that 42 patients were proportioned, 85 patients were moderately disproportioned, and 76 patients were severely disproportioned. Mechanical complications occurred with increasing GAPB in the proportioned group, but were not statistically significant (p = 0.0534). However, mechanical complications occurred in a statistically significant manner in the moderately disproportioned and severely disproportioned groups as GAPB increased (p < 0.001).
Conclusion
The GAPB system showed improved predictability for mechanical complications after surgery for ASD in each category of the GAP score.

Citations

Citations to this article as recorded by  Crossref logo
  • Machine learning clustering reveals risk factors of mechanical complications requiring revision in adult spinal deformity surgery: a 2-year follow-up study
    Alice Baroncini, Daniel Larrieu, Anouar Bourghli, Javier Pizones, Ferran Pellisè, Frank Kleinstueck, Ahmet Alanay, Yann Philippe Charles, Cecile Roscop, Louis Boissiere, Ibrahim Obeid
    European Spine Journal.2026; 35(1): 167.     CrossRef
  • Cost Benefit of Implementation of Risk Stratification Models for Adult Spinal Deformity Surgery
    Peter G. Passias, Tyler K. Williamson, Nicholas A. Kummer, Ferran Pellisé, Virginie Lafage, Renaud Lafage, Miguel Serra-Burriel, Justin S. Smith, Breton Line, Shaleen Vira, Jeffrey L. Gum, Sleiman Haddad, Francisco Javier Sánchez Pérez-Grueso, Andrew J. S
    Global Spine Journal.2025; 15(2): 818.     CrossRef
  • Predicting postoperative mechanical complications with the ethnicity-adjusted global alignment and proportion score in degenerative scoliosis: does paraspinal muscle degeneration matter?
    Peiyu Li, Jie Li, Abdukahar Kiram, Zhen Tian, Xing Sun, Xiaodong Qin, Benlong Shi, Yong Qiu, Zhen Liu, Zezhang Zhu
    The Spine Journal.2025; 25(2): 347.     CrossRef
  • The Association of Bone Mineral Density with Distal Junctional Kyphosis and Distal Junctional Failure After Multilevel Spine Fusions: A Systematic Review and Meta-Analysis
    Zeyad Daher, Luke L. Jouppi, Bryan G. Anderson, Clifford Pierre, Donald David Davis, Neel Patel, Julius Gerstmeyer, Gautam Rao, Daniel Norvell, Giorgio Cracchiolo, Amir Abdul-Jabbar, Rod Oskouian, Jens R. Chapman
    World Neurosurgery.2025; 195: 123598.     CrossRef
  • Alignment Goals in Adult Spinal Deformity Surgery
    Javier Pizones, Jeffrey Hills, Michael P. Kelly, Fatemeh Alavi, Susana Nuñez-Pereira, Justin S. Smith, Zeeshan M. Sardar, Lawrence G. Lenke, Stephen J. Lewis, Ferran Pellisé
    Global Spine Journal.2025;[Epub]     CrossRef
  • The predictive value of the global alignment and proportion (GAP) score for mechanical complications following adult spinal deformity surgery: A systematic review and meta-analysis
    Vinicius Ricieri Ferraz, Guilherme Santos Piedade, Carlos R. Goulart, Maria Fernanda Ricieri Ferraz Franco de Souza, Marcelo Ochoa Coelho de Souza Furlan, Philippe A. Mercier, Tobias A. Mattei
    North American Spine Society Journal (NASSJ).2025; 24: 100816.     CrossRef
  • Persistent Lower Extremity Compensation for Sagittal Imbalance After Surgical Correction of Complex Adult Spinal Deformity: A Radiographic Analysis of Early Impact
    Tyler K. Williamson, Pooja Dave, Jamshaid M. Mir, Justin S. Smith, Renaud Lafage, Breton Line, Bassel G. Diebo, Alan H. Daniels, Jeffrey L. Gum, Themistocles S. Protopsaltis, D. Kojo Hamilton, Alex Soroceanu, Justin K. Scheer, Robert Eastlack, Michael P.
    Operative Neurosurgery.2024; 26(2): 156.     CrossRef
  • Gravity Line–Hip Axis Offset as a Guide for Global Alignment to Prevent Recurrent Proximal Junctional Kyphosis/Failure
    Seung-Jae Hyun, Sungjae An, Byoung-Joo Park, Jae-Koo Lee, Seung Heon Yang, Ki-Jeong Kim
    Operative Neurosurgery.2024; 26(3): 268.     CrossRef
  • Assessing the predictive power of the GAP score on mechanical complications: a comprehensive systematic review and meta-analysis
    Minseong Cho, Sanghoon Lee, Ho-Joong Kim
    European Spine Journal.2024; 33(4): 1311.     CrossRef
  • Which sagittal plane assessment method is most predictive of complications after adult spinal deformity surgery?
    Javier Pizones, Jeffrey Hills, Michael Kelly, Caglar Yilgor, Lucía Moreno-Manzanaro, Francisco Javier Sánchez Perez-Grueso, Frank Kleinstück, Ibrahim Obeid, Ahmet Alanay, Ferran Pellisé
    Spine Deformity.2024; 12(4): 1127.     CrossRef
  • Deep Learning Method for Precise Landmark Identification and Structural Assessment of Whole-Spine Radiographs
    Sung Hyun Noh, Gaeun Lee, Hyun-Jin Bae, Ju Yeon Han, Su Jeong Son, Deok Kim, Jeong Yeon Park, Seung Kyeong Choi, Pyung Goo Cho, Sang Hyun Kim, Woon Tak Yuh, Su Hun Lee, Bumsoo Park, Kwang-Ryeol Kim, Kyoung-Tae Kim, Yoon Ha
    Bioengineering.2024; 11(5): 481.     CrossRef
  • The T4-L1-Hip Axis: Sagittal Spinal Realignment Targets in Long-Construct Adult Spinal Deformity Surgery
    Jeffrey Hills, Gregory M. Mundis, Eric O. Klineberg, Justin S. Smith, Breton Line, Jeffrey L. Gum, Themistocles S. Protopsaltis, D. Kojo Hamilton, Alex Soroceanu, Robert Eastlack, Pierce Nunley, Khaled M. Kebaish, Lawrence G. Lenke, Richard A. Hostin, Mun
    Journal of Bone and Joint Surgery.2024; 106(23): e48.     CrossRef
  • Determining the utility of three-column osteotomies in revision surgery compared with primary surgeries in the thoracolumbar spine: a retrospective cohort study in the United States
    Tyler Kade Williamson, Oluwatobi O Onafowokan, Ankita Das, Jamshaid Mahmood Mir, Oscar Krol, Peter Tretiakov, Rachel Joujon-Roche, Bailey Imbo, Salman Ahmad, Stephane Owusu-Sarpong, Jordan Lebovic, Shaleen Vira, Andrew J Schoenfeld, Muhammad Burhan Janjua
    Asian Spine Journal.2024; 18(5): 673.     CrossRef
  • Crossing the Bridge From Degeneration to Deformity: When Does Sagittal Correction Impact Outcomes in Adult Spinal Deformity Surgery?
    Tyler K. Williamson, Oscar Krol, Peter Tretiakov, Rachel Joujon-Roche, Bailey Imbo, Salman Ahmad, Stephane Owusu-Sarpong, Jordan Lebovic, Rivka Ihejirika-Lomedico, Michael Dinizo, Shaleen Vira, Ekamjeet Dhillon, Brooke O’Connell, Constance Maglaras, Andre
    Spine.2023; 48(3): E25.     CrossRef
  • Postoperative Gravity Line-Hip Axis Offset as a Substantial Risk Factor for Mechanical Failure After Adult Spinal Deformity Correction Surgery
    Sungjae An, Seung-Jae Hyun, Jae-Koo Lee, Seung Heon Yang, Ki-Jeong Kim
    Neurosurgery.2023; 92(5): 998.     CrossRef
  • Commentary on “Cervical Inclination Angle: Normative Values in an Adult Multiethnic Asymptomatic Population”
    Sung Hyun Noh, Yoon Ha
    Neurospine.2023; 20(1): 410.     CrossRef
  • Risk factors for unplanned reoperation after corrective surgery for adult spinal deformity
    Seung-Jun Ryu, Jae-Young So, Yoon Ha, Sung-Uk Kuh, Dong-Kyu Chin, Keun-Su Kim, Yong-Eun Cho, Kyung-Hyun Kim
    Bone & Joint Research.2023; 12(4): 245.     CrossRef
  • Sagittal realignment: surgical restoration of the global alignment and proportion score parameters: a subgroup analysis. What are the consequences of failing to realign?
    Riccardo Raganato, Javier Pizones, Caglar Yilgor, Lucía Moreno-Manzanaro, Alba Vila-Casademunt, José Miguel Sánchez-Márquez, Nicomedes Fernández-Baíllo, Francisco Javier Sánchez Pérez-Grueso, Frank Kleinstück, Ahmet Alanay, Ibrahim Obeid, Ferran Pellisé
    European Spine Journal.2023; 32(6): 2238.     CrossRef
  • Predicting Mechanical Complications After Adult Spinal Deformity Operation Using a Machine Learning Based on Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density
    Sung Hyun Noh, Hye Sun Lee, Go Eun Park, Yoon Ha, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Sang Hyun Kim, Kyung Hyun Kim
    Neurospine.2023; 20(1): 265.     CrossRef
  • Should Global Realignment Be Tailored to Frailty Status for Patients Undergoing Surgical Intervention for Adult Spinal Deformity?
    Peter G. Passias, Tyler K. Williamson, Oscar Krol, Peter S. Tretiakov, Rachel Joujon-Roche, Bailey Imbo, Salman Ahmad, Claudia Bennett-Caso, Stephane Owusu-Sarpong, Jordan B. Lebovic, Djani Robertson, Shaleen Vira, Ekamjeet Dhillon, Andrew J. Schoenfeld,
    Spine.2023; 48(13): 930.     CrossRef
  • Lumbar fusion through the anterolateral mini-approach: comparison of anterior interbody (OLIF-AF) and percutaneous pedicle (OLIF-PF) fixations in the surgical treatment of single-level stenosis
    Aleksandr Petrovich Saifullin, Alexandr Yakovlevich Aleynik, Andrei Evgenyevich Bokov, Sergey Gennadyevich Mlyavykh
    Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika).2023; 20(3): 50.     CrossRef
  • Relationship Between Hounsfield Units of Upper Instrumented Vertebrae, Proximal Junctional Failure, and Global Alignment and Proportion Score in Female Patients with Adult Spinal Deformity
    Akihiko Hiyama, Daisuke Sakai, Hiroyuki Katoh, Masato Sato, Masahiko Watanabe
    World Neurosurgery.2022; 164: e706.     CrossRef
  • Reciprocal Changes in the Whole-Body Following Realignment Surgery in Adult Spinal Deformity
    Jae-Koo Lee, Seung-Jae Hyun, Ki-Jeong Kim
    Asian Spine Journal.2022; 16(6): 958.     CrossRef
  • Assessing the influence of modifiable patient-related factors on complication rates after adult spinal deformity surgery
    Tyler K. Williamson, Lara Passfall, Rivka Ihejirika-Lomedico, Annie Espinosa, Stephane Owusu-Sarpong, Tomi Lanre-Amos, Andrew J. Schoenfeld, Peter G. Passias
    The Bone & Joint Journal.2022; 104-B(11): 1249.     CrossRef
  • 9,564 View
  • 142 Download
  • 27 Web of Science
  • 24 Crossref
Characteristics and Risk Factors of Rod Fracture Following Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis
Sung Hyun Noh, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Keun Su Kim, Yong Eun Cho, Dong Kyu Chin
Neurospine 2021;18(3):447-454.   Published online September 30, 2021
DOI: https://doi.org/10.14245/ns.2040832.416

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Characteristics and Risk Factors of Rod Fracture Following Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis
Neurospine. 2021;18(3):447-454.   Published online September 30, 2021
DOI: https://doi.org/10.14245/ns.2040832.416
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Characteristics and Risk Factors of Rod Fracture Following Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis
Neurospine. 2021;18(3):447-454.   Published online September 30, 2021
DOI: https://doi.org/10.14245/ns.2040832.416
Close
Objective
The aim of study is to investigate the features and risk factors of rod fracture (RF) following adult spinal deformity (ASD) surgery.
Methods
We searched the PubMed, Embase, Web of Science, and Cochrane Library databases to identify relevant studies. Patient’s data including age, sex, body mass index (BMI), previous spine surgery, pedicle subtraction osteotomy (PSO), interbody fusion, fusion to the pelvis, smoking history, preoperative sagittal vertical axis (SVA), preoperative pelvic tilt (PT), preoperative pelvic incidence minus lumbar lordosis, preoperative thoracic kyphosis (TK), and change in the SVA were documented. Comparable factors were evaluated using odds ratio (OR) and weighted mean difference (WMD) with 95% confidence interval (CI).
Results
Seven studies were included. The overall incidence of RF following ASD surgery was 12%. Advanced age (WMD, 2.8; 95% CI, 1.01–4.59; p < 0.002), higher BMI (WMD, 1.98; 95% CI, 0.65–3.31; p = 0.004), previous spine surgery (OR, 1.47; 95% CI, 1.05–2.04; p = 0.02), PSO (OR, 2.28; 95% CI, 1.62–3.19; p < 0.0001), a larger preoperative PT (WMD, 6.17; 95% CI, 3.55–8.97; p < 0.00001), and a larger preoperative TK (WMD, 5.19; 95% CI, 1.41–8.98; p = 0.007) were identified as risk factors for incidence of RF.
Conclusion
The incidence of RF in patients following ASD surgery was 12%. Advanced age, higher BMI, previous spine surgery, and PSO were significantly associated with an increased occurrence of RF. A larger preoperative PT and TK were also identified as risk factors for occurrence of RF following ASD surgery.

Citations

Citations to this article as recorded by  Crossref logo
  • Striking a Balance: The Role of Alignment, Surgical Techniques, and Multi-Rod Constructs in Reducing Rate of Rod Fractures in Adult Spinal Deformity Surgery
    Schahin Salmanian, Jay Kumar, César Carballo Cuello, Diego Soto Rubio, Mark Greenberg, Erik Hayman, Mohsen Rostami, Puya Alikhani
    Global Spine Journal.2026; 16(4): 1754.     CrossRef
  • What Factors Were Associated With Implant Failure After Posterior Vertebral Column Resection for Severe Thoracolumbar Pott Deformity?
    Junlong Zhong, Jingtao Gao, Jiachao Xiong, Lu Chen, Mardan Mamat, Yingsong Wang, Zhaohui Ge, Shengbiao Ma, Zhenhai Zhou, Yoon Ha, Kai Cao
    Clinical Orthopaedics & Related Research.2026; 484(5): 989.     CrossRef
  • Different Risk Factors of Rod Fracture between L5-S1 and ≥ L4-5 Levels in Adult Spinal Deformity Surgery
    Dong-Ho Kang, Jin-Sung Park, Se-Jun Park
    Clinics in Orthopedic Surgery.2026; 18(2): 281.     CrossRef
  • The lower Osteotomy Level is Associated With Decreased Revision Surgery Due to Mechanical Complications After Three-Column Osteotomy in Patients With Adult Spinal Deformity: A Multi-Institutional Retrospective Study
    Atsuyuki Kawabata, Kenichiro Sakai, Kentaro Yamada, Kurando Utagawa, Jun Hashimoto, Shingo Morishita, Yu Matsukura, Takuya Oyaizu, Takashi Hirai, Hiroyuki Inose, Masaki Tomori, Ichiro Torigoe, Hiroaki Onuma, Kazuo Kusano, Kazuyuki Otani, Yoshiyasu Arai, S
    Global Spine Journal.2025; 15(2): 498.     CrossRef
  • Impact of multi-rod reinforcement on rod fractures in adult spinal deformity: A retrospective case series with a minimum follow up of 5 years
    Yu Yamato, Tomohiko Hasegawa, Go Yoshida, Tomohiro Banno, Shin Oe, Hideyuki Arima, Koichiro Ide, Tomohiro Yamada, Kenta Kurosu, Keiichi Nakai, Yukihiro Matsuyama
    Journal of Orthopaedic Science.2025; 30(1): 51.     CrossRef
  • Factors associated with rod fracture following surgery for adult spinal deformity: a single-center retrospective study
    Hiroki Konuma, Junya Katayanagi, Takahiro Iida, Shingo Morishita, Tomoyuki Tanaka, Tsukasa Yanase, Tetsuya Jinno, Hiroyuki Inose
    Spine Deformity.2025; 13(2): 481.     CrossRef
  • A Virtual Response Surface Strategy to Predict the Effects of Contouring on the Static and Fatigue Mechanical Behavior of Spinal Rods
    Linda Carpenedo, Francesca Berti, Luigi La Barbera
    Annals of Biomedical Engineering.2025; 53(3): 644.     CrossRef
  • A comprehensive review of risk factors and prevention strategies: how to minimize mechanical complications in corrective surgery for adult spinal deformity
    Jin-Sung Park, Hyun-Jun Kim, Se-Jun Park, Dong-Ho Kang, Chong-Suh Lee
    Asian Spine Journal.2025; 19(3): 463.     CrossRef
  • Risk Factors for Rod Fracture at ≥L4-5 Levels Following Long-Segment Fusion for Adult Spinal Deformity: Results from Segment-Based Analysis
    Se-Jun Park, Jin-Sung Park, Chong-Suh Lee, Dong-Ho Kang
    Journal of Clinical Medicine.2025; 14(16): 5643.     CrossRef
  • Social Media as a Tool for Spinal Implant Identification: Insights from 100 Cases Analyzed in an Online Facebook Group
    Robin M. Litten, Omar Zakieh, James F. Bathon, Byron F. Stephens
    Spine Research.2025; 1(2): 78.     CrossRef
  • A stratified analysis of multilevel direct decompression of degenerative lumbar central stenosis: Is fusion needed in the elderly?
    Samuel Ezeonu, Juan Rodriguez Rivera, Alyssa Capasso, Nicholas Vollano, Constance Maglaras, Tina Raman
    Journal of Craniovertebral Junction and Spine.2025; 16(4): 444.     CrossRef
  • Gravity Line–Hip Axis Offset as a Guide for Global Alignment to Prevent Recurrent Proximal Junctional Kyphosis/Failure
    Seung-Jae Hyun, Sungjae An, Byoung-Joo Park, Jae-Koo Lee, Seung Heon Yang, Ki-Jeong Kim
    Operative Neurosurgery.2024; 26(3): 268.     CrossRef
  • Correlation Between Rod Fracture and Shear Stress: A Novel Parameter
    Seth Street, Abhijith V. Matur, Xu Tao, Geet Shukla, Julia Garcia-Vargas, Jay Mehta, Kelly Childress, Justin Gibson, Daryn Cass, Andrew Wu, Henry O. Duah, Benjamin Motley, Daniel Webb, Joseph Cheng, Owoicho Adogwa
    World Neurosurgery.2024; 183: e268.     CrossRef
  • Connecting the S2 alar-iliac screw head to the satellite rod for surgical correction of degenerative sagittal imbalance
    Sung Tan Cho, Dong-Ho Lee, Jae Hwan Cho, Sehan Park, Jin Hwan Kim, Mi Young Lee, So Jeong Yoon, Chang Ju Hwang
    European Spine Journal.2024; 33(5): 1850.     CrossRef
  • Sagittal alignment of diverse mechanical complications following adult spinal deformity surgery
    Changyu Pan, Anouar Bourghli, Daniel Larrieu, Louis Boissiere, Javier Pizones, Ahmet Alanay, Ferran PelIise, Frank Kleinstück, Ibrahim Obeid
    European Spine Journal.2024; 33(5): 1857.     CrossRef
  • What Are the Risk Factors for Mechanical Failure in Spinal Arthrodesis? An Observational Study
    Vincenzo Peccerillo, Antonio Culcasi, Riccardo Ruisi, Francesca Amaducci, Maria Grazia Benedetti, Marco Girolami, Andrea Evangelista, Mattia Morri
    Surgical Techniques Development.2024; 13(1): 87.     CrossRef
  • Pedicle Subtraction Osteotomies for Surgical Correction of Fixed Sagittal Imbalance: A Meta-Analysis and Systematic Review
    Pratheek S. Makineni, Mohamed E. El-Abtah, Joshua R. Porto, Michael P. Steinmetz, Edward C. Benzel
    Neurosurgery.2024; 95(6): 1223.     CrossRef
  • Instrumentation Failure in Adult Spinal Deformity Patients
    David P. Falk, Ravi Agrawal, Bijan Dehghani, Rohit Bhan, Sachin Gupta, Munish C. Gupta
    Journal of Clinical Medicine.2024; 13(15): 4326.     CrossRef
  • Novel assessment of physiotherapy outcomes in adults with structural spinal disorders
    Keita Sato, Toshikazu Ito, Tatsuya Endo, Takuya Miura, Masumi Iwabuchi, Osamu Shirado
    European Spine Journal.2023; 32(6): 1887.     CrossRef
  • Postoperative complications in adult spinal deformity surgery: An overview of timing, risk factors, and management strategies
    Andy Ton, Raymond J. Hah
    Seminars in Spine Surgery.2023; 35(2): 101031.     CrossRef
  • Multiple-Rod Constructs in Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis
    Jian Zhao, Zheng Nie, Zhengping Zhang, Dongfa Liao, Da Liu
    Asian Spine Journal.2023; 17(5): 985.     CrossRef
  • Mechanical Failure After Total En Bloc Spondylectomy and Salvage Surgery
    Shin Won Kwon, Chun Kee Chung, Young Il Won, Woon Tak Yuh, Sung Bae Park, Seung Heon Yang, Chang Hyun Lee, John M. Rhee, Kyoung-Tae Kim, Chi Heon Kim
    Neurospine.2022; 19(1): 146.     CrossRef
  • Systematic review and meta-analysis for the impact of rod materials and sizes in the surgical treatment of adult spine deformity
    Dawn Bowden, Annalisa Michielli, Michelle Merrill, Steven Will
    Spine Deformity.2022; 10(6): 1265.     CrossRef
  • Complications and management in adult spinal deformity
    Andrew Jae-Min Park, Addisu Mesfin
    Seminars in Spine Surgery.2022; 34(4): 100993.     CrossRef
  • Surgical outcome of minimal invasive oblique lateral interbody fusion with percutaneous pedicle screw fixation in the treatment of adult degenerative scoliosis
    Jun Seok Lee, Dong Wuk Son, Su Hun Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song, Young Ha Kim, Chang Hwa Choi
    Medicine.2022; 101(48): e31879.     CrossRef
  • 9,308 View
  • 186 Download
  • 26 Web of Science
  • 25 Crossref

Case Report

Late-Developing Metastatic Malignant Melanoma in the Thoracic Spine Originating from Choroidal Melanoma
Jun Kyu Hwang, Kyung Hyun Kim, Ji Sup Kim, Sung Jun Ahn, Sung Uk Kuh
Korean J Spine 2017;14(2):53-56.   Published online June 30, 2017
DOI: https://doi.org/10.14245/kjs.2017.14.2.53

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Late-Developing Metastatic Malignant Melanoma in the Thoracic Spine Originating from Choroidal Melanoma
Korean J Spine. 2017;14(2):53-56.   Published online June 30, 2017
DOI: https://doi.org/10.14245/kjs.2017.14.2.53
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Late-Developing Metastatic Malignant Melanoma in the Thoracic Spine Originating from Choroidal Melanoma
Korean J Spine. 2017;14(2):53-56.   Published online June 30, 2017
DOI: https://doi.org/10.14245/kjs.2017.14.2.53
Close
A 54-year-old woman visited Gangnam Severance Hospital for left side flank pain. She had a history of total removal of malignant melanoma on the left eye ball 20 years prior. No evaluation had been performed since then. A paravertebral mass at thoracic ninth level (T9) was discovered on spinal magnetic resonance imaging, and pathology confirmed malignant melanoma. Following positron emission tomography-computed tomography, no other metastasis was discovered. After removal of the paravertebral mass, palliative chemotherapy (dacabarzine + tamoxifene) was administered in 3 cycles over 2 months. Radiotherapy with simultaneous integrated boost technique was performed at 4,350 cGy total over 15 days, 290 cGy per delivery, and was administered with the first cycle of palliative chemotherapy. Despite this treatment, multiple metastases developed throughout her body 7 months later, and the patient is continuing chemotherapy.

Citations

Citations to this article as recorded by  Crossref logo
  • Choroidal melanoma with extensive skeletal metastasis in a 20-year patient
    Nikhil Kumar, Lata Singh, Aanchal Kakkar, Rachna Meel, Seema Kashyap
    Indian Journal of Ophthalmology - Case Reports.2025; 5(3): 523.     CrossRef
  • Reporting a Case of Cervical Vertebral Body Primary Malignant Melanoma—A Rare Entity
    G Krishna Kumar, Chandrasekhar Chigurupalli, Anandh Balasubramaniam, BJ Rajesh, Pooja Chavali
    Neurology India.2022; 70(Suppl 2): S310.     CrossRef
  • Choroid Melanoma Metastasis to Lumbar Spine: A Case Report
    Yeo Song Kim, Jeong Gyun Kim, Jong Joo Rhee, Jong Won Lee, Hyun Koo Lee, Jin Woo Hur
    The Nerve.2020; 6(2): 120.     CrossRef
  • Prognostic factors of patients with spinal malignant melanoma after surgical intervention: a case series of 21 patients and literature review
    Zhichao Zhang, Haiyi Gong, Chenglong Zhao, Dongsheng Wang, Ming Qian, Zhipeng Wu, Jianru Xiao
    Journal of Neuro-Oncology.2019; 142(1): 119.     CrossRef
  • 11,968 View
  • 121 Download
  • 4 Crossref

Clinical Articles

Bone Mineral Density Changes after Orchiectomy using a Scrotal Approach in Rats
Seong Jun Ryu, Dal Sung Ryu, Jong Yul Kim, Jeong Yoon Park, Kyung Hyun Kim, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Sung Uk Kuh
Korean J Spine 2015;12(2):55-59.   Published online June 30, 2015
DOI: https://doi.org/10.14245/kjs.2015.12.2.55

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Bone Mineral Density Changes after Orchiectomy using a Scrotal Approach in Rats
Korean J Spine. 2015;12(2):55-59.   Published online June 30, 2015
DOI: https://doi.org/10.14245/kjs.2015.12.2.55
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Bone Mineral Density Changes after Orchiectomy using a Scrotal Approach in Rats
Korean J Spine. 2015;12(2):55-59.   Published online June 30, 2015
DOI: https://doi.org/10.14245/kjs.2015.12.2.55
Close
Objective

To investigate a suitable animal model for studies of male osteoporosis. Osteoporosis has a particularly high incidence in postmenopausal women, resulting in a substantial amount of research with respect to this disease in women. However, research on osteoporosis in men is still lacking.

Methods

Twenty 10-week-old male Sprague Dawley rats were used in this study, including 4 rats used to establish a baseline bone mineral density (BMD). The other 16 rats were divided into two groups: a sham surgery group (n=8), which underwent a sham operation, and an orchiectomized rat group (OCX) (n=8), which underwent bilateral OCX at 10 weeks of age. Bone mineral density was measured in 4 rats from both the sham surgery group and the OCX group 8 weeks after the surgery, while BMD in the remainder of the rats was measured 10 weeks post-surgery.

Results

Femoral BMD at 8 weeks post-surgery was found to be significantly lower in the OCX group compared to the sham group; a finding that was also similar 10 weeks post-surgery.

Conclusion

8 weeks after undergoing orchiectomy performed via a scrotal, white rats are a suitable model for studies of male osteoporosis.

Citations

Citations to this article as recorded by  Crossref logo
  • The antiosteoporotic effect of oxymatrine compared to testosterone in orchiectomized rats
    Anwaar M. Shaban, Eman A. Ali, Sara G. Tayel, Sara Kamal Rizk, Dalia F. El Agamy
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • Promotion of Bone Formation in a Rat Osteoporotic Vertebral Body Defect Model via Suppression of Osteoclastogenesis by Ectopic Embryonic Calvaria Derived Mesenchymal Stem Cells
    Yerin Yu, Somin Lee, Minsung Bock, Seong Bae An, Hae Eun Shin, Jong Seop Rim, Jun-oh Kwon, Kwang-Sook Park, Inbo Han
    International Journal of Molecular Sciences.2024; 25(15): 8174.     CrossRef
  • Effects on Bone and Muscle upon Treadmill Interval Training in Hypogonadal Male Rats
    Ioannis Stratos, Ingmar Rinas, Konrad Schröpfer, Katharina Hink, Philipp Herlyn, Mario Bäumler, Tina Histing, Sven Bruhn, Brigitte Müller-Hilke, Michael D. Menger, Brigitte Vollmar, Thomas Mittlmeier
    Biomedicines.2023; 11(5): 1370.     CrossRef
  • Sex Hormone Suppression and Physical Activity: Possible Implications for Transgender Individuals
    David S. Hydock
    Transgender Health.2022; 7(1): 43.     CrossRef
  • Korean Medicine Treatment for Managing Complex Regional Pain Syndrome: Case Report
    Ji-won Park, Myung-In Jeong, Wu-Jin Jeong, Hae-Won Hong, Ji-eun Koo, Sung-won Choi, Da-hyun Kyung
    Journal of Acupuncture Research.2022; 39(3): 234.     CrossRef
  • Physiological testosterone replacement effects on male aged rats with orchiectomy-induced osteoporosis in advanced stage: a tomographic and biomechanical pilot study
    Vinícius de Paiva Gonçalves, Adriana Alicia Cabrera-Ortega, Jhonatan de Souza Carvalho, Dania Ramadan, Luís Carlos Spolidorio
    The Aging Male.2021; 24(1): 139.     CrossRef
  • What Causes the Discrepancy between Quantitative Computed Tomography and Dual Energy X-Ray Absorptiometry?
    Hong Yoon, Jung-Ho Kim, Dal-Sung Ryu, Seung-Hwan Yoon
    The Nerve.2021; 7(2): 64.     CrossRef
  • Effects of 12 Weeks Resistance Exercise on Blood Testosterone, DHT and Bone-Related Metabolism in Orchiectomized Rats
    Kyung A Back, Se Hwan Park, Jin Hwan Yoon
    Exercise Science.2020; 29(2): 138.     CrossRef
  • Effect of Selective Androgen Receptor Modulator Enobosarm on Bone Healing in a Rat Model for Aged Male Osteoporosis
    Marina Komrakova, Janek Nagel, Daniel Bernd Hoffmann, Wolfgang Lehmann, Arndt Friedrich Schilling, Stephan Sehmisch
    Calcified Tissue International.2020; 107(6): 593.     CrossRef
  • Impact of Dehydroepiandrosterone (DHEA) on Bone Mineral Density and Bone Mineral Content in a Rat Model of Male Hypogonadism
    Hussein F. Sakr, Abdelaziz M. Hussein, Elsayed A. Eid, Ammar Boudaka, Lashin S. Lashin
    Veterinary Sciences.2020; 7(4): 185.     CrossRef
  • La prêle des champs : une plante médicinale d'avenir
    M. Ben Laiba, W. Douki, R. Chemli
    Phytothérapie.2018; 16(2): 108.     CrossRef
  • Changes in Bone Metabolism in Young Castrated Male Rats
    Seong-Jun Ryu, Dal-Sung Ryu, Jong-Yeol Kim, Jeong-Yoon Park, Kyung-Hyun Kim, Dong-Kyu Chin, Keun-Su Kim, Yong-Eun Cho, Sung-Uk Kuh
    Yonsei Medical Journal.2016; 57(6): 1386.     CrossRef
  • 10,915 View
  • 99 Download
  • 12 Crossref
A PET/CT-based Morphometric Study of Spinal Canal in Korean Young Adults: Anteroposterior Diameter from Cervical Vertebra to Sacrum
Moo Sung Kang, Jeong Yoon Park, Dong Kyu Chin, Kyung Hyun Kim, Sung Uk Kuh, Keun Su Kim, Yong Eun Cho
Korean J Spine 2012;9(3):165-169.   Published online September 30, 2012
DOI: https://doi.org/10.14245/kjs.2012.9.3.165

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

A PET/CT-based Morphometric Study of Spinal Canal in Korean Young Adults: Anteroposterior Diameter from Cervical Vertebra to Sacrum
Korean J Spine. 2012;9(3):165-169.   Published online September 30, 2012
DOI: https://doi.org/10.14245/kjs.2012.9.3.165
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
A PET/CT-based Morphometric Study of Spinal Canal in Korean Young Adults: Anteroposterior Diameter from Cervical Vertebra to Sacrum
Korean J Spine. 2012;9(3):165-169.   Published online September 30, 2012
DOI: https://doi.org/10.14245/kjs.2012.9.3.165
Close
Objective

To establish normative data for spinal canal AP diameter from cervical vertebra to sacrum in the Korean young and to assess the exposed spinal canal after laminectomy which was related with restenosis by post-laminectomy membrane formation.

Methods

From PET/CT, axial bone-window CT of 83 young adults (20-29 years) were obtained, and we measured AP diameters of C3, C5, C7, T1, T4, T8, T12, L1, L3, L5 and S1. We also measured exposed AP diameter of C3, C5, C7, T1 and T2 above imaginary line for laminectomy.

Results

The shortest mean AP diameter was at C5 (14.5±1.5 mm), and the longest was at S1 (17.4±2.3 mm). AP diameter increased from C3 (14.6±1.1 mm) to T1 (16.1±1.2 mm) at cervical spine. In the thoracic spine, the diameter gradually decreased from T1 (16.1±1.2 mm) to T8 (14.6±1.3 mm) and increased to T12 (16.7±1.2 mm). The diameter decreased from L1 (16.7±1.3 mm) to L3 (15.7±1.9 mm), and it increased to S1 (17.4±2.3 mm) at lumbar spine. Exposed AP diameter above imaginary line for laminectomy was the longest at C3 (4.8±1.2 mm) and gradually decreased to T1 (3.3±0.9 mm) and T2 (0 mm).

Conclusions

Spinal AP diameter was the shortest in the mid-cervical area (C5) and increased to the upper thoracic area. From the upper thoracic vertebra, the diameter gradually decreased to the mid-thoracic vertebra (T8) and then increased to the lower thoracic vertebra. Lumbar vertebra also was similar with thoracic vertebra. Below T2, there was no exposed dural sac after laminectomy. This means that restenosis by post-laminectomy membrane formation can occur above T1.

Citations

Citations to this article as recorded by  Crossref logo
  • Characteristics of infectious spondylitis patients with normal white blood cell count and C-reactive protein level and associated factors
    Hyeon Jae Jo, Sook-In Jung, Eu Suk Kim, Kyoung-Ho Song, Kyung-Hwa Park, Nam Joong Kim
    BMC Infectious Diseases.2026;[Epub]     CrossRef
  • Accuracy of Thoracolumbar Pedicle Screws Using Routine O-Arm Intraoperative Navigation—A 15-Year Review With Over 5000 Screws. A New Benchmark?
    Alexander Shao-Rong Pang, Fang Nian Joanne Lim, Pirateb Paramasivam Meenakshi Sundaram, Jacob Yoong-Leong Oh
    Spine.2026; 51(7): E169.     CrossRef
  • Diagnostic Value of Flow-Void Sign for Localizing Ventral Dural Defects in Spine MRI
    Soo-Im Jang, Soyoun Choi, Seung Ae Kim, Hoe Jong Jeong, Ja-Young Choi, Mi Ji Lee
    Journal of Clinical Neurology.2026; 22(3): 364.     CrossRef
  • Smaller thoracic canal diameters are associated with thoracic radiculopathy and abdominal pain after spinal cord stimulator paddle lead placement
    Brian T. Ragel, Matthew McGehee, Nicolas Karvelas, Ahmed M. Raslan
    Pain Practice.2025;[Epub]     CrossRef
  • Tumour distribution and characteristics associated with poor surgical outcomes in patients with sporadic spinal schwannomas
    Shinsuke Yoshida, Takaaki Suzuki, Masayuki Tanabe, Kazuo Saita
    Acta Neurochirurgica.2025;[Epub]     CrossRef
  • Analysis of spinal canal diameter in the placement of thoracic spinal cord stimulator paddle leads
    Brian T. Ragel, Tressa Riedman, Matthew McGehee, Ahmed M. Raslan
    Pain Practice.2024; 24(1): 91.     CrossRef
  • Delayed development of spinal stenosis at the spinal cord stimulator percutaneous lead entry point: case report and literature review
    Hunter Xavier Leech, David Anthony Provenzano, Leonard DeRiggi, David Oliver-Smith
    Regional Anesthesia & Pain Medicine.2024; 49(8): 615.     CrossRef
  • Rostral migration of intradural bullet from lumbar to thoracic spine: Case report and review of the literature
    Mikael Aseged Shimekit, Aemro Mazengia Andualem, Kaleab Tesfaye Reda, Mahelt Getachew Lemma
    Interdisciplinary Neurosurgery.2023; 34: 101862.     CrossRef
  • Natural history of spinal cord arteriovenous shunts: an observational study
    Jia-Xing Yu, Tao Hong, Timo Krings, Chuan He, Ming Ye, Li-Yong Sun, Xiao-Dong Zhai, Si-Shi Xiang, Yong-Jie Ma, Li-Song Bian, Jian Ren, Peng-Yu Tao, Jing-Wei Li, Fan Yang, Gui-Lin Li, Feng Ling, Hong-Qi Zhang
    Brain.2019; 142(8): 2265.     CrossRef
  • Biometrics of the Cervical Spinal Canal and Cord by Computer Tomography in Togo
    Abdoulatif Amadou, Lantam Sonhaye, Kossivi Apetse, Komlan Amoussou, Mazamaesso Tchaou, Bidamin N’timon, Kahabilou Atsa Agbangba, Gani Watara, Komlavi Adjenou
    Open Journal of Radiology.2017; 07(01): 45.     CrossRef
  • 15,330 View
  • 117 Download
  • 10 Crossref

Original Article

The Clinical and Radiological Characteristics of Male Patients who Underwent Vertebroplasty Due to Osteoporotic Compression Fracture.
Je Beom Hong, Kyung Hyun Kim, Jeong Yoon Park, Dong Kyu Chin, Sung Uk Kuh, Yong Eun Cho
Korean J Spine 2011;8(3):178-182.
DOI: https://doi.org/10.14245/kjs.2011.8.3.178

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

The Clinical and Radiological Characteristics of Male Patients who Underwent Vertebroplasty Due to Osteoporotic Compression Fracture.
Korean J Spine. 2011;8(3):178-182.
DOI: https://doi.org/10.14245/kjs.2011.8.3.178
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
The Clinical and Radiological Characteristics of Male Patients who Underwent Vertebroplasty Due to Osteoporotic Compression Fracture.
Korean J Spine. 2011;8(3):178-182.
DOI: https://doi.org/10.14245/kjs.2011.8.3.178
Close
OBJECTIVE
To investigate the clinical characteristics of male population who underwent vertebroplasty for osteoporotic compression fracture and evaluate the clinical, radiological outcomes compared to female group.
METHODS
The medical records and radiological data were reviewed in total 155 patients who underwent vertebroplasty for osteoporotic vertebral compression fracture from February 2006 to November 2009. We compared 32 male patients with 123 female patients in terms of preoperative factors, intraoperative factors, and clinical and radiologic outcomes.
RESULTS
The mean age of male group was 67.8~8.6 years and their mean T-score on bone mineral density (BMD) was -3.2+/-0.8. The mean age of female group was 71.8+/-8.9 years and their mean T-score was -3.7+/-0.7 (p=0.025 for age, p=0.002 for BMD). Male patients (21 out of 32, 65.6%) had more frequent traumatic event than female patients (51 out of 123, 41.5%) (p=0.012). The secondary osteoporosis was more frequently seen in male group than female group (53.1% vs 26.8%, p=0.005). The lump cement distribution pattern was found more frequently in male group than female group (46.9% vs 28.5%, p=0.040). There was no statistically significant difference between the two groups in clinical outcomes.
CONCLUSION
Male patients had significantly more risk factors for secondary osteoporosis and obvious traumatic event than female group. Clinicians should always be aware of secondary causes of osteoporosis and history of traumatic events in male patients with osteoporotic compression fracture and also pay attention to correct the cause of secondary osteoporosis and recommend anti-osteoporosis management.
  • 4,991 View
  • 28 Download

Case Report

Rapid Spontaneous Resolution of Idiopathic Cervico-thoracic Ventral Epidural Hematoma.
Jong Yul Kim, Kyung Hyun Kim, Sung Uk Kuh, Yong Eun Cho
Korean J Spine 2010;7(3):202-205.

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Rapid Spontaneous Resolution of Idiopathic Cervico-thoracic Ventral Epidural Hematoma.
Korean J Spine. 2010;7(3):202-205.
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Rapid Spontaneous Resolution of Idiopathic Cervico-thoracic Ventral Epidural Hematoma.
Korean J Spine. 2010;7(3):202-205.
Close
Spontaneous spinal epidural hematoma (SSEH) has been rarely reported in the literature. Prompt surgical intervention is recommended for patients with neurologic deficit. However. in rare cases, spontaneous resolution of the SSEH with recovery of the neurological deficit has also been reported. We report a case of SSEH in a 55-year-old woman with a rapidly progressing neurological deficit. Her neurological deficits gradually improved sponta- neously during preoperative evaluation. Serial magnetic resonance imaging(MRI) demonstrated disappearance of the hematoma. Since her neurological status improved within a few hours, we recommended conservative care. Patients initially presenting with severe neurologic dysfunction are potential candidates for conservative management if they demonstrate rapid and progressive improvement in neurologic function. Thus, immediate surgical decompression may not be necessary if neuroimaging and clinical examinations suggest that spinal epidural hematoma will spontaneously resolve.
  • 3,369 View
  • 32 Download

Original Article

Surgical Treatment of Degenerative Lumbar Spine Disease in Geriatric Patients Over 70 Years Old: A Review of Two Decades.
Seung Bok Wee, Sung Sam Jung, Ki Seok Park, Sung Uk Kuh
Korean J Spine 2008;5(3):161-166.

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Surgical Treatment of Degenerative Lumbar Spine Disease in Geriatric Patients Over 70 Years Old: A Review of Two Decades.
Korean J Spine. 2008;5(3):161-166.
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Surgical Treatment of Degenerative Lumbar Spine Disease in Geriatric Patients Over 70 Years Old: A Review of Two Decades.
Korean J Spine. 2008;5(3):161-166.
Close
OBJECTIVE
The aim of this study is to evaluate the transition of lumbar spinal treatments for geriatric patients over 70 years old over two decades.
METHODS
We retrospectively assessed 730 patients who were 70 years and older and underwent lumbar surgery. We analyzed the number of diseases, operation methods and complications with 5-year intervals from 1987 to 2006. RESULT: The number of patients older than 70 years who underwent lumbar surgery increased according to our analysis of the period spanning from 1987 to 2006. Thirty-two (1%), 77 (1.7%), 232 (4.4%), and 389 (8.2%) patients over 70 years underwent lumbar spine surgeries. Among them, the 8, 29 and 45 patients had one level degenerative spondylolisthesis for the periods 1992-1996, 1997-2001 and 2002-2006. Twenty-four, 29 and 58 patients had lumbar stenosis during all these time periods. Over time, we performed a larger variety of operations as well as more aggressive operations. From January 2002 to December 2006, a total of 308 patients were over 70 years old and had lumbar spine surgeries performed on them. Among them, the ASA class I was 58 (19%), the ASA class II was 213 (69%) and the ASA class III was 37 (12%). During that period, PLIFs and PS fixations were performed on 69 patients. Among them, 8 patients were ASA III. Large numbers of lumbar arthorodesis have been performed in geriatric patients over the age of 70 years in our series.
CONCLUSION
The surgical treatment of degenerative spine disease in the elderly patients was increased due to improved surgical technique and advances in medical treatment including anesthesia. The authors suggest that fusion surgery can be done safely in elderly patients even though they have high-grade ASA classification.
  • 3,229 View
  • 21 Download
First First Prev Prev
Page of 1
Next Next Last Last
NS : Neurospine
Facebook Twitter