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Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly
Neurospine. 2021;18(1):226-233.   Published online March 31, 2021
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Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly
Neurospine. 2021;18(1):226-233.   Published online March 31, 2021
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Objective
The objective of the current study was to perform a retrospective review of a national database to assess the safety of cement augmentation for vertebral compression fractures in geriatric populations in varying age categories.
Methods
The 2005–2016 National Surgical Quality Improvement Program databases were queried to identify patients undergoing kyphoplasty or vertebroplasty in the following age categories: 60–69, 70–79, 80–89, and 90+ years old. Demographic variables, comorbidity status, procedure type, provider specialty, inpatient/outpatient status, number of procedure levels, and periprocedure complications were compared between age categories using chi-square analysis. Multivariate logistic regressions controlling for patient and procedural variables were then performed to assess the relative periprocedure risks of adverse outcomes of patients in the different age categories relative to those who were 60–69 years old.
Results
For the 60–69, 70–79, 80–89, and 90+ years old cohorts, 486, 822, 937, and 215 patients were identified, respectively. After controlling for patient and procedural variables, 30-day any adverse events, serious adverse events, reoperation, readmission, and mortality were not different for the respective age categories. Cases in the 80- to 89-year-old cohort were at increased risk of minor adverse events compared to cases in the 60- to 69-year-old cohort.
Conclusion
As the population ages, cement augmentation is being considered as a treatment for vertebral compression fractures in increasingly older patients. These results suggest that even the very elderly may be appropriately considered for these procedures (level of evidence: 3).

Citations

Citations to this article as recorded by  Crossref logo
  • Surgical management of spinal metastases from primary lung carcinoma: demographics, clinical characteristics, and outcomes—A retrospective analysis
    Jun Li, Yuhan Zheng, Xiaohua Lv, Rong Zeng, Yating Zhao, Yucheng Xiang, Ke Zhan, Congcong Liu, Houqing Long, Ke Chen
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Advantages of TiRobot-assisted surgery in the treatment of osteoporotic thoracolumbar compression fractures: a meta-analysis based on multiple clinical indicators
    Yu Liu, Zidong Xia, Huiling Chen, Jian Wang, Mengtian Cao, Guohang Shen, Mingyuan Fan, Kaiyong Wang, Yang Chen, Yupei Dai
    Journal of Robotic Surgery.2025;[Epub]     CrossRef
  • Spinal augmentation for vertebral body fractures in the elderly population
    Alexander R. Evans, Taylor Niznik, Chao Li, Zachary A. Smith
    GeroScience.2025;[Epub]     CrossRef
  • The future of ambulatory surgery for geriatric patients
    Mary Ann Vann
    Best Practice & Research Clinical Anaesthesiology.2023; 37(3): 343.     CrossRef
  • What are the risk factors for a second osteoporotic vertebral compression fracture?
    Sang Hoon Hwang, Pyung Goo Cho, Kyoung-Tae Kim, Keung Nyun Kim, Sang Hyun Kim, Sung Hyun Noh
    The Spine Journal.2023; 23(11): 1586.     CrossRef
  • Beyond Pain Relief: An In-Depth Review of Vertebral Height Restoration After Balloon Kyphoplasty in Vertebral Compression Fractures
    Siddharth K Patel, Sohael Khan, Ventaktesh Dasari, Suvarn Gupta
    Cureus.2023;[Epub]     CrossRef
  • Risk of Revision After Vertebral Augmentation for Osteoporotic Vertebral Fracture: A Narrative Review
    Shinji Takahashi, Hiroyuki Inose, Koji Tamai, Masayoshi Iwamae, Hidetomi Terai, Hiroaki Nakamura
    Neurospine.2023; 20(3): 852.     CrossRef
  • The Effectiveness of Vertebral Height Restoration Based on the Vertebroplasty Procedure Used to Treat Osteoporotic Vertebral Fractures
    Kunio Yokoyama, Naokado Ikeda, Hidekazu Tanaka, Yutaka Ito, Akira Sugie, Makoto Yamada, Masahiko Wanibuchi, Masahiro Kawanishi
    Neurospine.2023; 20(4): 1159.     CrossRef
  • Treatment for Osteoporotic Vertebral Fracture - A Short Review of Orthosis and Percutaneous Vertebroplasty and Balloon Kyphoplasty
    Masahiro Kawanishi, Hidekazu Tanaka, Yutaka Ito, Makoto Yamada, Kunio Yokoyama, Akira Sugie, Naokado Ikeda
    Neurospine.2023; 20(4): 1124.     CrossRef
  • Commentary on “Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty”
    Sahir S. Jabbouri, Peter G. Whang
    Neurospine.2023; 20(4): 1140.     CrossRef
  • Difference in the Cobb Angle Between Standing and Supine Position as a Prognostic Factor After Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures
    In-Suk Bae, Byung Gwan Moon, Hee In Kang, Jae Hoon Kim, Cheolsu Jwa, Deok Ryeong Kim
    Neurospine.2022; 19(2): 357.     CrossRef
  • Kyphoplasty: why, when and how?
    Umile Giuseppe Longo, Rocco Papalia, Sergio De Salvatore, Valentina Piccioni, Vincenzo Denaro
    International Journal of Bone Fragility.2022; 2(1): 41.     CrossRef
  • 11,311 View
  • 222 Download
  • 11 Web of Science
  • 12 Crossref

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Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years)
Neurospine. 2020;17(1):156-163.   Published online July 5, 2019
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Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years)
Neurospine. 2020;17(1):156-163.   Published online July 5, 2019
Close
Objective
Anterior cervical discectomy and fusion (ACDF) is the most commonly performed procedure for degenerative cervical spondylosis. Because of its relatively low invasiveness and surgical procedure, old age is not regarded as an exclusion criterion for ACDF. However, very few studies have been conducted on the radiological and clinical outcomes of ACDF in older patients. The purpose of this study was to evaluate the radiological and clinical outcomes of ACDF in older patients.
Methods
We retrospectively analyzed 48 patients (> 65 years) who underwent ACDF from January 2011 to December 2015. We divided the patients into 2 groups: young-old age group (65–74 years) and middle-old age group (≥ 75 years). Cervical lateral radiographs taken in the neutral standing position were evaluated preoperatively (PRE), on postoperative day 7 (POST), and at the 1-year follow-up (F/U). The radiological parameters included cervical angle (CA: C2–7 Cobb angle), segmental angle, total intervertebral height, disc height, sagittal vertical axis (SVA), T1 slope (T1s), and range of cervical motion (extension CA minus flexion CA). Postoperative hospital days, comorbidities, complications, and clinical outcomes were also analyzed.
Results
We analyzed data from 48 patients (group A: n = 30 patients, 46 segments, mean age, 68.60 ± 3.36 years; group B: n = 18 patients, 23 segments, mean age, 79.22 ± 2.63 years). The surgical levels were as follows: C3/4, 4; C4/5, 7; C5/6, 10; C6/7, 29; and C7/ T1, 6 levels, and there were no significant between-group differences in the distribution. There were no significant between-group differences in the fusion and subsidence rates (fusion rate: group A, 76.2%; group B, 71.4%; p = 0.732; subsidence rate: group A, 34.8%; group B, 26.1%; p = 0.587). There was no longitudinal trend in the repeated-measurements analysis of variance test of the 2 groups of the PRE, POST, and F/U data for each radiological parameter. According to the paired t-test, T1 slope (T1s), SVA, and CA did not differ preoperatively and postoperatively. There was no statistically significant difference in visual analogue scale scores (axial, arm), the Neck Disability Index, or Odom’s criteria between the 2 groups (p = 0.448, p = 0.357, and p = 0.913).
Conclusion
There was no significant difference in radiological and clinical outcomes between young-old and middle-old patients. Middle-old age does not seem to be a limitation to ACDF, but larger-scale and longer-term studies are needed to confirm the findings of this study.

Citations

Citations to this article as recorded by  Crossref logo
  • Impact of enhanced recovery after surgery (ERAS) protocols in elderly patients undergoing lumbar fusion: a systematic review with meta-analysis and trial sequential analysis
    Yantong Zhang, Gang Chen, Mengting Xu, Huiqing Gao, Renji Zheng, Wenqin Lv, Zhiping Yin, Yingfeng Zhou, Jun Li, Shaowu Jin
    European Spine Journal.2026; 35(4): 2001.     CrossRef
  • Radiological Factors Affecting Cage Subsidence after Single-level Anterior Cervical Discectomy and Fusion with Double Titanium Cylindrical Cages
    Toshiyuki OKAZAKI, Kazuma DOI, Kazunori SHIBAMOTO, Satoshi TANI, Junichi MIZUNO
    Neurologia medico-chirurgica.2026; 66(1): 7.     CrossRef
  • Predictors of Surgical Outcome After Anterior Cervical Discectomy and Fusion: A Prospective Middle Eastern Cohort Study
    Ahmed Al-Atraqchi, Rawan Alatraqchi, Yasoob A Alaameri
    Cureus.2026;[Epub]     CrossRef
  • Do Elderly Patients Achieve Comparable Functional and Quality-of-Life Improvements After Anterior Cervical Discectomy and Fusion for Degenerative Cervical Myelopathy?
    Jeremy Tze En Lim, Gerald Joseph Zeng, Graham S. Goh, Ming Han Lincoln Liow, Reuben Chee Cheong Soh, Chang Ming Guo, John Li-Tat Chen
    Global Spine Journal.2026;[Epub]     CrossRef
  • Does Back Pain Improve Following Lumbar Decompression Alone?
    David J. Mazur-Hart, Christian G. Lopez Ramos, Joseph G. Nugent, Brannan E. O’Neill, Barry Cheaney, Hanne A. Gehling, Jamila Godil, Brandi W. Pang, Arilene Novak, James T. Obayashi, Travis C. Philipp, Clifford Lin, Jung U. Yoo, Christina H. Wright, James
    Clinical Spine Surgery.2025;[Epub]     CrossRef
  • Surgical management of spinal pathologies in the octogenarian: a narrative review
    Alexander R. Evans, Joshua Bakhsheshian, Christopher S. Graffeo, Zachary A. Smith
    GeroScience.2024; 46(4): 3555.     CrossRef
  • Impact of age within younger populations on outcomes following cervical surgery in the ambulatory setting
    Timothy J. Hartman, James W. Nie, Hanna Pawlowski, Michael C. Prabhu, Nisheka N. Vanjani, Kern Singh
    Journal of Clinical Orthopaedics and Trauma.2022; 34: 102016.     CrossRef
  • Sagittal balance of the cervical spine: a systematic review and meta-analysis
    Parisa Azimi, Taravat Yazdanian, Edward C. Benzel, Yong Hai, Ali Montazeri
    European Spine Journal.2021; 30(6): 1411.     CrossRef
  • Predictors associated with neurological recovery after anterior decompression with fusion for degenerative cervical myelopathy
    Hiroyuki Inose, Takashi Hirai, Toshitaka Yoshii, Atsushi Kimura, Katsushi Takeshita, Hirokazu Inoue, Asato Maekawa, Kenji Endo, Takeo Furuya, Akira Nakamura, Kanji Mori, Shunsuke Kanbara, Shiro Imagama, Shoji Seki, Shunji Matsunaga, Kunihiko Takahashi, At
    BMC Surgery.2021;[Epub]     CrossRef
  • Efficacy for Whitlockite for Augmenting Spinal Fusion
    Su Yeon Kwon, Jung Hee Shim, Yu Ha Kim, Chang Su Lim, Seong Bae An, Inbo Han
    International Journal of Molecular Sciences.2021; 22(23): 12875.     CrossRef
  • Commentary on “Surgical and Functional Outcomes of Expansive Open-Door Laminoplasty for Patients With Mild Kyphotic Cervical Alignment”
    Dongwuk Son
    Neurospine.2021; 18(4): 758.     CrossRef
  • 13,456 View
  • 248 Download
  • 9 Web of Science
  • 11 Crossref