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NASS/Neurospine Endoscopic Spine Surgery Special Issue

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Spinal Canal Remodeling and Indirect Decompression of Contralateral Foraminal Stenosis After Endoscopic Posterolateral Transforaminal Lumbar Interbody Fusion
Neurospine. 2023;20(1):99-109.   Published online March 31, 2023
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Spinal Canal Remodeling and Indirect Decompression of Contralateral Foraminal Stenosis After Endoscopic Posterolateral Transforaminal Lumbar Interbody Fusion
Neurospine. 2023;20(1):99-109.   Published online March 31, 2023
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Objective
There is a lack of literature on indirect decompression in uniportal endoscopic posterolateral transforaminal lumbar interbody fusion (EPTLIF). Our aim is to evaluate the dimensions of the spinal canal and contralateral foramen before and after EPTLIF.
Methods
This is a retrospective study of patients who underwent EPTLIF in a tertiary spine centre over a 2-year period. The cross-sectional area of the spinal canal and the contralateral foramen at the level of fusion were measured on magnetic resonance imaging scan at 1-day postoperation and at the final follow-up. Patients were grouped according to the decompression performed as per the clinician’s judgement.
Results
One hundred fifty-two levels of fusion were performed in 120 patients. There was a statistically significant clinical improvement in visual analogue scale and Oswestry Disability Index scores postoperation. The measurements of the spinal canal area were 106.0 mm2, 138.8 mm2, and 195.5 mm2; while contralateral foraminal area were 73.2 mm2, 104.4 mm2, and 120.7 mm2 at preoperation, 1-day postoperation, and at the final follow-up, respectively (p < 0.001). For the subgroup analyses, spinal canal area measurements for the bilateral decompression cohort (n = 35) were 57.0 mm2, 123.9 mm2, and 191.8 mm2; for the ipsilateral decompression cohort (n = 42) were 89.3 mm2, 128.9 mm2, 183.3 mm2; and for the cohort without any decompression and only cage inserted (n = 75) were 138.3 mm2, 151.2 mm2, and 204.1 mm2 (p < 0.001). Contralateral foraminal area measurements were 73.3 mm2, 106.4 mm2 and 120.4 mm2 in the bilateral decompression cohort; 69.5 mm2, 99.0 mm2, 116.9 mm2 in the ipsilateral decompression cohort; and 75.1 mm2, 106.5 mm2, 122.9 mm2 in the cohort without any decompression (p < 0.001).
Conclusion
Indirect decompression of both the spinal canal and the contralateral foramen can be achieved via EPTLIF. Decompression on an asymptomatic contralateral side is not necessary.

Citations

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  • Computed tomography imaging for exploring the appropriate angle of a visible Trephine in endoscopic spine lumbar interbody fusion
    Wei Wang, Yukai Cui, Xiaohao Sun, Wen Yin, Xilong Cui, Haiyang Yu, Wenjie Diao, Wenbo Diao, Wei Jiao
    European Spine Journal.2026; 35(6): 3448.     CrossRef
  • Robot-assisted unilateral biportal endoscopic lumbar interbody fusion for lumbar spondylolisthesis: ipsilateral direct with contralateral indirect decompression
    Han Yi, Siyang He, Senglin Zhang, Peng Liu, Shu Lin, Kun Zhang, Jiang Hu, Fei Wang, Fang Tang, Wei Zhang
    BMC Musculoskeletal Disorders.2026;[Epub]     CrossRef
  • Outcomes in Lumbar Fusion Patients Stratified by the Clinical and Radiographic Degenerative Spondylolisthesis (CARDS) Classification System
    Justin J Turcotte, Jane C Brennan, Parimal Rana, Andrea H Johnson, Chad Patton
    Cureus.2024;[Epub]     CrossRef
  • Trends in degenerative lumbar spinal surgery during the early COVID-19 pandemic in Republic of Korea: A national study utilizing the national health insurance database
    Woon Tak Yuh, Jinhee Kim, Mi-Sook Kim, Jun-Hoe Kim, Young Rak Kim, Sum Kim, Chun Kee Chung, Chang-Hyun Lee, Sung Bae Park, Kyoung-Tae Kim, John M. Rhee, Young San Ko, Chi Heon Kim, Kentaro Yamada
    PLOS ONE.2024; 19(6): e0305128.     CrossRef
  • Can unilateral-transforaminal lumbar interbody fusion replace the traditional transforaminal lumbar interbody fusion procedure for lumbar degenerative disc diseases?: a single center matched case-control mid-term outcome study
    Sajan Karunakar Hegde, Appaji Krishnamurthy Krishnan, Vigneshwara Badikkillaya, Sharan Talacauvery Achar, Harith Baddula Reddy, Akshyaraj Alagarasan, Rochita Venkataramanan
    Asian Spine Journal.2024; 18(6): 846.     CrossRef
  • 8,386 View
  • 230 Download
  • 5 Web of Science
  • 5 Crossref

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Psychometric Properties of the Scoliosis Research Society Questionnaire (Version 22r) Domains Among Adults With Spinal Deformity: A Rasch Measurement Theory Analysis
Neurospine. 2022;19(2):422-433.   Published online May 15, 2022
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Psychometric Properties of the Scoliosis Research Society Questionnaire (Version 22r) Domains Among Adults With Spinal Deformity: A Rasch Measurement Theory Analysis
Neurospine. 2022;19(2):422-433.   Published online May 15, 2022
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Objective
Adult spinal deformity (ASD) have lower health-related quality of life (HRQoL) compared to the general population. Applying Rasch measurement theory (RMT), this study tested the revised Scoliosis Research Society-22 (SRS-22r) HRQoL instrument among symptomatic adult patients with degenerative spinal disorders and varying degrees of ASD.
Methods
SRS-22r data from 637 outpatient spine clinic patients with degenerative spine conditions were investigated for unidimensionality, item/scale fit, differential item functioning (DIF), scale coverage/targeting, and person separation index (PSI) using RMT.
Results
Unidimensionality of the SRS-22r was not supported for either the total score or for 3 of its 5 domains. Item fit was acceptable for 11/22 items. The individual domains showed good coverage despite the degree of structural disorders. Ordered thresholds were achieved by merging response categories in some of the items. DIF towards age or sex was found in 11/22 items and in some domain items. The PSI exceeded 0.7 for the SRS-22r total score.
Conclusion
The individual domain scores of the SRS-22r perform better than the total score providing good coverage and targeting among patients with ASD. Refinements of items and domains may improve the structural validity of the instrument to meet the criteria for measuring ASD patients, even when multidimensionality persists.

Citations

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  • Beyond the curve: The impact of trunk and shoulder symmetry on self-image and mental health in adolescent idiopathic scoliosis
    A. Shiju Majeed, B.P. Vinodkumar, N. Ajina
    Journal of Orthopaedic Reports.2026; : 100897.     CrossRef
  • Course and Predictors of Adult Spinal Sagittal Disorders
    Heidi Mannström, Juhani Multanen, Jari Ylinen, Arto Hautala, Arttu Peuna, Lauri Karttunen, Liisa Pekkanen, Kati Kyrölä
    Spine.2025; 50(8): 522.     CrossRef
  • Validation of the Oswestry Disability Index in Adult Spinal Deformity
    Omid Jalali, Justin S. Smith, Shay Bess, Richard Hostin, Renaud Lafage, Virginie Lafage, Christopher I. Shaffrey, Christopher P. Ames, Lawrence G. Lenke, Michael P. Kelly
    Spine.2024; 49(10): 682.     CrossRef
  • Development and Preliminary Testing of the Staffordshire Questionnaire for Adolescent Idiopathic Scoliosis (SQ‐AIS): Content and Face Validity
    Enza Leone, Nachiappan Chockalingam, Robert Needham, Aoife Healy, Nicola Eddison, Nikola Jevtic, Vinay Jasani
    Health Science Reports.2024;[Epub]     CrossRef
  • 9,646 View
  • 209 Download
  • 4 Web of Science
  • 4 Crossref

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Ossification of the Posterior Longitudinal Ligament: Surgical Approaches and Associated Complications
Neurospine. 2019;16(3):517-529.   Published online September 30, 2019
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Ossification of the Posterior Longitudinal Ligament: Surgical Approaches and Associated Complications
Neurospine. 2019;16(3):517-529.   Published online September 30, 2019
Close
Ossification of the posterior longitudinal ligament (OPLL) is a rare but potentially devastating cause of degenerative cervical myelopathy (DCM). Decompressive surgery is the standard of care for OPLL and can be achieved through anterior, posterior, or combined approaches to the cervical spine. Surgical correction of OPLL via any approach is associated with higher rates of complications and the presence of OPLL is considered a significant risk factor for perioperative complications in DCM surgeries. Potential complications include dural tear (DT) and subsequent cerebrospinal fluid leak, C5 palsy, hematoma, hardware failure, surgical site infections, and other neurological deficits. Anterior approaches are technically more demanding and associated with higher rates of DT but offer greater access to ventral OPLL pathology. Posterior approaches are associated with lower rates of complications but may allow for continued disease progression. Therefore, the decision to pursue either an anterior or posterior approach to surgical decompression may be critically influenced by complications associated with each procedure. The authors critically review anterior and posterior approaches to surgical decompression of OPLL with particular focus on the complications associated with each approach. We also review the recent work in developing new surgical treatments for OPLL that aim to reduce complication incidence.

Citations

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    Yusuke Setojima, Kengo Fujii, Toru Funayama, Toshitaka Yoshii, Satoru Egawa, Takashi Hirai, Hiroshi Takahashi, Masashi Yamazaki, Masao Koda
    The Spine Journal.2026; 26(1): 119.     CrossRef
  • Identifying biomechanical and neurophysiological risk factors for postoperative neurologic deterioration in OPLL surgery: A study using ROC curve and path analysis
    Jinyoung Park, Seungjun Ryu, Young Seok Kim, Myungeun Yoo, Hyo Jeong Lee, Chae Hwan Lim, Seok Young Chung, Dawoon Kim, Yong Eun Cho, Yoon Ghil Park
    European Spine Journal.2026; 35(4): 1771.     CrossRef
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    Pengfei Shen, Xingchen Huo, Yufei Yuan, Shuangquan Gao, Xiaoman Dong, Jun Miao
    Journal of Orthopaedics.2026; 75: 225.     CrossRef
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    ChenGuang Wang, ChengHan Xu, YinGang Zhang
    Journal of Orthopaedic Surgery and Research.2026;[Epub]     CrossRef
  • Angiogenesis in ossification of the posterior longitudinal ligament: progress from mechanism to targeted intervention
    Xiaoyu Liu, Xiaomin Wang, Kangyi Hu, Haonan Wen, Lu Liu, Haoxing Li, Zhixin Che, Ting Song, Jinquan Lai, Min Song, Yongjia Song
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  • Spinal Cord Myelopathies
    Jennifer Padwal, Tarik F. Massoud, Syed S. Hashmi
    Neuroimaging Clinics of North America.2026;[Epub]     CrossRef
  • Comparative Analysis of Outcomes and Kyphotic Risk Factors After Cervical Laminoplasty in 2 Different Ossification of the Posterior Longitudinal Ligament Groups and Cervical Spondylotic Myelopathy
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    Neurosurgery.2025; 97(2): 320.     CrossRef
  • Cervical spondylotic myelopathy and radiculopathy: a stepwise approach and comparative analysis of surgical outcomes: a narrative review of recent literature
    Min-Woo Kim, Ye-Soo Park, Chang-Nam Kang, Sung Hoon Choi
    Asian Spine Journal.2025; 19(1): 121.     CrossRef
  • Hand Dexterity Recovery Capacity for Degenerative Cervical Myelopathy With Varying Levels of Impairment: A Prospective 1-Year Follow-up Study
    Guoyan Liang, Tianying Liao, Yongyu Ye, Yi Cai, Junying Chen, Yunbing Chang
    Neurospine.2025; 22(1): 202.     CrossRef
  • Impact of frailty on short- and long-term outcomes following cervical laminoplasty for ossification of the posterior longitudinal ligament: a retrospective cohort study
    Xing Cheng, Wenlin Ye, Zhengran Yu, Chong Chen, Tao Yu, Jianxiong Zhuang, Dan Xiao, Yongxiong Huang, Yunbing Chang
    European Spine Journal.2025; 34(8): 3345.     CrossRef
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    Xiao Chen, Yuanhe Fan, Jie Chen, Hongliang Tu
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
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    European Spine Journal.2025; 34(12): 5590.     CrossRef
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    Dong Soon Jang, Hakyung Kim, Seung Hun Sheen, Inbo Han, Soo Hyun Lee, Woo Seok Choi, Je Beom Hong, Min Jai Cho, Seil Sohn
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    Young-Il Ko, Young-Hoon Kim, Jorge Barraza, Myung-Sup Ko, Chungwon Bang, Byung Jun Hwang, Sang-Il Kim, Hyung-Youl Park
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    Tong Yongjun, Xie Yaming, Chen Biao, Yang Yonghong, Zhao Xinhua
    Orthopaedic Surgery.2022; 14(10): 2788.     CrossRef
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    Cheng Li, Yunli Mei, Lei Li, Zeqing Li, Shuai Huang
    Orthopaedic Surgery.2022; 14(9): 2361.     CrossRef
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    Jian Guan, Chenghua Yuan, Yueqi Du, Shanhang Jia, Can Zhang, Zhenlei Liu, Kai Wang, Wanru Duan, Zuowei Wang, Xingwen Wang, Hao Wu, Zan Chen, Fengzeng Jian
    European Spine Journal.2022; 31(12): 3462.     CrossRef
  • Late-Onset Cervical Pseudomeningocele Following Ossification of the Posterior Longitudinal Ligament Surgery Successfully Treated With a Lumboperitoneal Shunt
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    Cureus.2022;[Epub]     CrossRef
  • Intraoperative O-arm navigation guided anterior cervical corpectomy and fusion with minimally invasive cervical pedicle screw fixation (MICEPS) for severe ossification of the cervical posterior longitudinal ligament (OPLL): A technical note
    Yoshihiro Fujiwara, Ying Tan, Venkatesh Kadiri, Koji Uotani, Taro Yamauchi, Masato Tanaka
    Interdisciplinary Neurosurgery.2021; 23: 100902.     CrossRef
  • Commentary: Microsurgical Anterior Controllable Antedisplacement Fusion to Treat Cervical Ossified Posterior Longitudinal Ligament: 2-Dimensional Operative Video
    Mehmet Zileli, Nevhis Akıntürk
    Operative Neurosurgery.2021; 20(3): E222.     CrossRef
  • Surgical strategy for non-continuous thoracic spinal stenosis: one- or two-stage surgery?
    Longjie Wang, Hui Wang, Zhongqiang Chen, Chuiguo Sun, Weishi Li
    International Orthopaedics.2021; 45(7): 1871.     CrossRef
  • Prediction of angular kyphosis after cervical laminoplasty using radiologic measurements
    Hyeongseok Jeon, Hyung-Cheol Kim, Tae Woo Kim, Seong Bae An, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Do Heum Yoon, Sachin A. Borkar, Dong Wuk Son, Yoon Ha
    Journal of Clinical Neuroscience.2021; 85: 13.     CrossRef
  • Surgical Options in Treating Ossification of the Posterior Longitudinal Ligament: Single-Center Experience
    Brian J. Park, Scott C. Seaman, Royce W. Woodroffe, Jennifer Noeller, Patrick W. Hitchon
    World Neurosurgery.2021; 148: e617.     CrossRef
  • Risk factors for surgical complications in the management of ossification of the posterior longitudinal ligament
    Miguel Rafael David Ramos, Gabriel Liu, Jun-Hao Tan, Jiong Hao Jonathan Tan, John N.M. Ruiz, Hwee Weng Dennis Hey, Leok-Lim Lau, Naresh Kumar, Joseph Thambiah, Hee-Kit Wong
    The Spine Journal.2021; 21(7): 1176.     CrossRef
  • Ossification of the Posterior Longitudinal Ligament in the Cervical, Thoracic, and Lumbar Spine
    Adriel Barrios-Anderson, Elaina J Wang, Rahul Sastry, Jared S Fridley
    Cureus.2021;[Epub]     CrossRef
  • Unveiling the genetic variation of severe continuous/mixed-type ossification of the posterior longitudinal ligament by whole-exome sequencing and bioinformatic analysis
    Chang-Hyun Lee, Ki Tae Kim, Chi Heon Kim, Eun Young Lee, Sang Gu Lee, Myung-Eui Seo, Ju Han Kim, Chun Kee Chung
    The Spine Journal.2021; 21(11): 1847.     CrossRef
  • Efficacy of Posterior Cervical Laminectomy for Multilevel Cervical Ossification of Posterior Longitudinal Ligament
    Sanjeev Asati, Vishal G. Kundnani, Shrikant S. Sagane, Sanyam Jain, Saijyot Raut
    Indian Spine Journal.2021; 4(2): 181.     CrossRef
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The Concept for A Standalone Lordotic Endoscopic Wedge Lumbar Interbody Fusion: The LEW-LIF
Neurospine. 2019;16(1):82-95.   Published online March 31, 2019
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The Concept for A Standalone Lordotic Endoscopic Wedge Lumbar Interbody Fusion: The LEW-LIF
Neurospine. 2019;16(1):82-95.   Published online March 31, 2019
Close
Objective
To review concepts of a standalone endoscopically assisted lumbar interbody fusion as a simplified method to treat spinal instability.
Methods
MacNab outcomes and complications were analyzed in a series of 48 consecutive patients who underwent standalone lordotic endoscopic wedge lumbar interbody fusion (LEW-LIF) for advanced lumbar disc degeneration, spinal stenosis, and spondylolisthesis.
Results
Forty-two of the 48 patients (77.8%) did well with excellent and good outcomes with a follow up of up to 20 months. Fair outcomes were reported by 4, and poor by another 2 patients, respectively. Six patients had endoscopic decompression procedures at another level. Four patients underwent open transforaminal lumbar interbody fusion revision surgery including the index level between 2 to 6 months postoperatively. An L5 vertebral body fracture was noted in 1 of these 4 patients. Another patient underwent removal of the extruded L3/4 cage. The cage fractured in one additional asymptomatic patient not requiring any intervention. No patient had a wound infection, or permanent sensory, or motor dysfunction. However, 29 patients developed a postoperative irritation of the dorsal root ganglion with burning leg pain typically between postoperative weeks 2 and 6. Symptoms were treated with activity modification, gabapentin, and transforaminal epidural steroid injections in 12 patients (25%).
Conclusion
Standalone LEW-LIF was associated with favorable clinical outcomes in the majority of patients. Patient-related predictors of less favorable outcomes considering normal variations as well as patho-anatomy may aid in the development of next-generation implants.

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    Prosthesis.2026; 8(3): 27.     CrossRef
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Gender Differences in the Self-assessment of Quality of Life and Disability After Spinal Fusion for Chronic Low Back Pain at a Neurosurgical Center in Eastern Europe
Neurospine. 2018;15(3):261-268.   Published online August 29, 2018
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Gender Differences in the Self-assessment of Quality of Life and Disability After Spinal Fusion for Chronic Low Back Pain at a Neurosurgical Center in Eastern Europe
Neurospine. 2018;15(3):261-268.   Published online August 29, 2018
Close
Objective
Mechanical alterations of the spine, which can cause chronic low back pain (LBP), are a frequent indication for spinal fusion. Studies have shown differences between genders in patients’ evaluations of health-related quality of life (HRQoL) after spinal procedures, but results have been conflicting, and some authors have suggested that cultural variation could explain these discrepancies. The objectives of this study were to determine the influence that gender plays on HRQoL, disability, and the correlation between the 2 in people undergoing spinal fusion for chronic LBP at a neurosurgical centre in Eastern Europe.
Methods
Patients undergoing fusion surgery at a single centre for LBP with a duration of more than 3 months were included. They were evaluated using the Short Form Health Survey version-2.0 (SF-36v2) and Oswestry Low Back Pain Disability Index (ODI) questionnaire preoperatively and 1 year after the surgical procedure to identify differences between genders and to evaluate correlations between disability and quality of life.
Results
We included 31 female and 30 male patients. The male patients had higher disability scores at the preoperative evaluation, but improved more than females in all domains of disability at the postoperative evaluation. HRQoL improved similarly in both genders. The ODI score showed a strong or moderate correlation with 6 of the domains of the SF-36 in males, but with only 3 domains in females. Surgery had a positive impact on the mental status of more men than women at risk of depression.
Conclusion
The type of benefit that surgery offers seems to be influenced by gender. While HRQoL improved in both genders, disability decreased significantly more in male patients. Male patients also showed a closer correlation between HRQoL and disability. We conclude that men and women place different importance on specific aspects of their overall quality of life.

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