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Metastatic Mixed Germ Cell Tumor at the Intramedullary Cervical Spine -A Case Report-
Seng-Oun Sung, M.D., Byung-Chan Jeon, M.D., Il-Sup Kim, M.D., Yong-Suk Park, M.D., Young-Soo Kim, Bang Huh, M.D.
Department of Neurosurgery and Pathology, College of Medicine, Kosin University Gospel Hospital, Busan, Korea
경추 수질부에 전이된 혼합 배아세포종 -증례 보고-
성승언ㆍ전병찬ㆍ김일섭ㆍ박용숙ㆍ김영수ㆍ허방
고신대학교 의과대학 신경외과학교실, 병리학교실
Abstract
The literature contains no report on metastatic mixed germ cell tumor at high cervical area. The authors report a patient with metastatic mixed germ cell tumor at craniovertebral junction, who recovered uneventfully after operation. A 31- year-old man was presented with sustained neck pain and slowly progressing quadriparesis. Seventeen years ago, he was operated and received radiation with chemotherapy for the treatment of germinoma on the pineal region, follo- wed by ventriculoperitoneal shunt. Preoperative cervical MRI showed mass lesion at C1-2 area with high signal on T2WI and heterogeneous enhancement on Gd-enhanced T1WI, and syringomyelia at cervicomedullary junction to C7. We performed biopsy based on a patient's past medical history and the laboratory findings: serum AFP and beta- hCG level. On the background of frozen biopsy suggesting mixed germ cell tumor, subtotal resection of the tumor was done with minimal morbidity. Pathologic report confirmed the tumor as mixed germ cell tumor. After operation, the patient recovered uneventfully. We report a rare case of metastatic intramedullary mixed germ cell tumor at high cervical region.
Keywords: Mixed Germ Cell Tumor Metastasis Intramedullary cervical spine


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