| Introduction |
| Bench to Bed (B2B) Project; Intervertebral Disc Degeneration in Collaboration With Biospine |
| Joo Han Kim |
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DOI: http://doi.org/10.14245/ns.2040110.055 |
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| Basic Research |
| Review Article |
| Gene Therapy Approach for Intervertebral Disc Degeneration: An Update |
| Yoshiki Takeoka, Takashi Yurube, Kotaro Nishida |
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DOI: http://doi.org/10.14245/ns.2040042.021 |
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| Editorials |
| Commentary on “Gene Therapy Approach for Intervertebral Disc Degeneration: An Update” |
| James D. Kang |
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DOI: http://doi.org/10.14245/ns.2040092.046 |
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| Moving Forward: Gene Therapy for Intervertebral Disc Degeneration |
| In-Bo Han |
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DOI: http://doi.org/10.14245/ns.2040108.054 |
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| Review Article |
| Wnt3a and wnt5a as Potential Chondrogenic Stimulators for Nucleus Pulposus Cell Induction: A Comprehensive Review |
| Tibo Nico Emmie Volleman, Jordy Schol, Kosuke Morita, Daisuke Sakai, Masahiko Watanabe |
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DOI: http://doi.org/10.14245/ns.2040040.020 |
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| Original Articles |
| Correlation of Early Outcomes and Intradiscal Interleukin-6 Expression in Lumbar Fusion Patients |
| John D. Koerner, Dessislava Z. Markova, Greg D. Schroeder, Christopher L. Antonacci, Joseph Mendelis, Alexander R. Vaccaro, D. Greg Anderson, Chris K. Kepler |
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DOI: http://doi.org/10.14245/ns.2040054.027 |
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| Direct and Intervertebral DiscMediated Sensitization of Dorsal Root Ganglion Neurons by Hypoxia and Low pH |
| Junxuan Ma, Despina Stefanoska, Sibylle Grad, Mauro Alini, Marianna Peroglio |
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DOI: http://doi.org/10.14245/ns.2040052.026 |
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| Actions of Prostaglandins on Human Nucleus Pulposus Metabolism Inferred by Cyclooxygenase 2 Inhibition of Cytokine Activated Cells |
| Nam Vo, Brandon Couch, Joon Lee, Gwendolyn Sowa, James Kang, Studer Rebecca |
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DOI: http://doi.org/10.14245/ns.2040050.025 |
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| Rabbit Annulus Fibrosus Cells Express Neuropeptide Y, Which Is Influenced by Mechanical and Inflammatory Stress |
| Malcolm E. Dombrowski, Adam S. Olsen, Nicholas Vaudreuil, Brandon K. Couch, Qing Dong, Michelle Tucci, Joon Y. Lee, Nam V. Vo, Gwendolyn Sowa |
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DOI: http://doi.org/10.14245/ns.2040046.023 |
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| Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype |
| Rahel D. May, Daniela A. Frauchiger, Christoph E. Albers, Willy Hofstetter, Benjamin Gantenbein |
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DOI: http://doi.org/10.14245/ns.2040002.001 |
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| New Technology |
| Review Articles |
| Robotic Spine Surgery and Augmented Reality Systems: A State of the Art |
| Gianluca Vadalà, Sergio De Salvatore, Luca Ambrosio, Fabrizio Russo, Rocco Papalia, Vincenzo Denaro |
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DOI: http://doi.org/10.14245/ns.2040060.030 |
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| Biomaterials in Spinal Implants: A Review |
| Andrew Warburton, Steven J. Girdler, Christopher M. Mikhail, Amy Ahn, Samuel K. Cho |
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DOI: http://doi.org/10.14245/ns.1938296.148 |
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| Editorial |
| Commentary on “Biomaterials in Spinal Implants: A Review” |
| Hans-Joerg Meisel, Neha Agarwal |
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DOI: http://doi.org/10.14245/ns.2040126.063 |
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| Original Article |
| Telerobotic Spinal Surgery Based on 5G Network: The First 12 Cases |
| Wei Tian, Mingxing Fan, Cheng Zeng, Yajun Liu, Da He, Qi Zhang |
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DOI: http://doi.org/10.14245/ns.1938454.227 |
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| Editorials |
| Remote Robotic Spine Surgery |
| John R. Adler |
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DOI: http://doi.org/10.14245/ns.2040088.044 |
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| The Future of Spine Surgery in the Fourth Industrial Revolution: Telerobotic Spine Surgery |
| Yong Eun Cho |
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DOI: http://doi.org/10.14245/ns.19227edi.001 |
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| Original Article |
| Polyetheretherketone Versus Titanium Cages for Posterior Lumbar Interbody Fusion: Meta-Analysis and Review of the Literature |
| Elie Massaad, Nida Fatima, Ali Kiapour, Muhamed Hadzipasic, Ganesh M. Shankar, John H. Shin |
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DOI: http://doi.org/10.14245/ns.2040058.029 |
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| Case Report |
| Smartphone-Based Self-Assessment of Objective Functional Impairment (6-Minute Walking Test) in Patients Undergoing Epidural Steroid Injection |
| Anna Maria Zeitlberger, Marketa Sosnova, Michal Ziga, Valentin Steinsiepe, Oliver P. Gautschi, Martin N. Stienen, Nicolai Maldaner |
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DOI: http://doi.org/10.14245/ns.2040022.011 |
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| Editorial |
| The Advent of Smartphone Applications in Spine Surgery: Bringing the Field to the 21st Century |
| Don Young Park |
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DOI: http://doi.org/10.14245/ns.2040066.033 |
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| Cervical Spine |
| Original Articles |
| Rigid-Plating and Cortico-Cancellous Allograft Are Effective for 3-Level Anterior Cervical Discectomy and Fusion: Radiographic and Clinical Outcomes |
| Philip K. Louie, Andrew C. Sexton, Danel D. Bohl, Ehsan Tabaraee, Steven M. Presciutti, Benjamin C. Mayo, Justin C. Paul, Comron Saifi, Howard S. An |
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DOI: http://doi.org/10.14245/ns.1836052.026 |
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| Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years) |
| Chi Hyung Lee, Dong Wuk Son, Su Hun Lee, Jun Seok Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song |
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DOI: http://doi.org/10.14245/ns.1836072.036 |
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| Degenerative Cervical Myelopathy: A 7-Letter Coding System That Supports Decision-Making for the Surgical Approach |
| Luca Papavero, Gregor Schmeiser, Ralph Kothe, Bronek Boszczyk, Oliver Heese, Yoshiharu Kawaguchi, Anna MacDowall, Claes Olerud, Nikolaos Paidakakos, Anastasios Panagiotou, Tobias Pitzen, Marcus Richter, K. Daniel Riew, Aaron Stevenson, Lee Tan, Ryo Ueshima, YH Yau, Michael Mayer |
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DOI: http://doi.org/10.14245/ns.1938010.005 |
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| Editorial |
| Commentary on “Degenerative Cervical Myelopathy: A 7-Letter Coding System That Supports Decision-Making for the Surgical Approach” |
| Oliver Hausmann |
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DOI: http://doi.org/10.14245/ns.2040100.050 |
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| Original Articles |
| Effect of the Presence and Type of Plate Augmentation on Postoperative Dysphagia Among Adult Patients Undergoing Elective Anterior Cervical Discectomy and Fusion for Spondylosis: A Randomized Trial |
| Tom J. O’Donohoe, Lisa Mililli, Alison Magee, Christopher Thien, Yi Yuen Wang |
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DOI: http://doi.org/10.14245/ns.1938446.223 |
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| Evaluation of Postoperative Mental Health Outcomes in Patients Based on Patient-Reported Outcome Measurement Information System Physical Function Following Anterior Cervical Discectomy and Fusion |
| Joon S. Yoo, Nathaniel W. Jenkins, James M. Parrish, Thomas S. Brundage, Nadia M. Hrynewycz, Franchesca A. Mogilevsky, Kern Singh |
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DOI: http://doi.org/10.14245/ns.1938256.128 |
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| The Impact of Modic Changes on Preoperative Symptoms and Clinical Outcomes in Anterior Cervical Discectomy and Fusion Patients |
| James D. Baker, Garrett K. Harada, Youping Tao, Philip K. Louie, Bryce A. Basques, Fabio Galbusera, Frank Niemeyer, Hans-Joachim Wilke, Howard S. An, Dino Samartzis |
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DOI: http://doi.org/10.14245/ns.2040062.031 |
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| Lumbar Spine and Spinal Deformity Surgery |
| Original Article |
| Timing of Surgery in Tubular Microdiscectomy for Lumbar Disc Herniation and Its Effect on Functional Impairment Outcomes |
| Alessandro Siccoli, Marlies P. de Wispelaere, Marc L. Schröder, Victor E. Staartjes |
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DOI: http://doi.org/10.14245/ns.1938448.224 |
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| Editorial |
| Surgical Timing in Lumbar Disc Herniation Surgery |
| Chi Heon Kim |
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DOI: http://doi.org/10.14245/ns.2040068.034 |
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| Original Articles |
| The Influence of Mechanic Factors in Disc Degeneration Disease as a Determinant for Surgical Indication |
| Gulden Demirci Otluoğlu, Deniz Konya, Zafer Orkun Toktas |
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DOI: http://doi.org/10.14245/ns.2040044.022 |
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| Image-Based Markers Predict Dynamic Instability in Lumbar Degenerative Spondylolisthesis |
| William Slikker III, Alejandro A. Espinoza Orías, Grant D. Shifflett, Joe Y.B. Lee, Krzysztof Siemionow, Sapan Gandhi, Louis Fogg, Dino Samartzis, Nozomu Inoue, Howard S. An |
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DOI: http://doi.org/10.14245/ns.1938440.220 |
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| Less Opioid Consumption With Enhanced Recovery After Surgery Transforaminal Lumbar Interbody Fusion (TLIF): A Comparison to Standard Minimally-Invasive TLIF |
| Hsuan-Kan Chang, Meng Huang, Jau-Ching Wu, Wen-Cheng Huang, Michael Y. Wang |
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DOI: http://doi.org/10.14245/ns.1938422.211 |
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| Use of Opioids and Other Analgesics Before and After Primary Surgery for Adult Spinal Deformity: A 10-Year Nationwide Study |
| Frederik Taylor Pitter, Matt Sikora, Martin Lindberg-Larsen, Alma Becic Pedersen, Benny Dahl, Martin Gehrchen |
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DOI: http://doi.org/10.14245/ns.1938106.053 |
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| Opioids and Spinal Cord Stimulators: Pre- and Postoperative Opioid Use Patterns and Predictors of Prolonged Postoperative Opioid Use |
| Lawal Labaran, Jomar N.A. Aryee, Joshua Bell, Nikhil Jain, Varun Puvanesarajah, Michael Raad, Amit Jain, Jonathan Carmouche, Hamid Hassanzadeh |
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DOI: http://doi.org/10.14245/ns.1938308.154 |
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| Comparison of the Safety and Effectiveness of Percutaneous Endoscopic Lumbar Discectomy for Treating Lumbar Disc Herniation Under Epidural Anesthesia and General Anesthesia |
| Zhiqiang Ren, Shenghua He, Jiao Li, Yeguang Wang, Juyi Lai, Zhitao Sun, Hualong Feng, Jian Wang |
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DOI: http://doi.org/10.14245/ns.1938366.183 |
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| The Navigated Oblique Lumbar Interbody Fusion: Accuracy Rate, Effect on Surgical Time, and Complications |
| Zhuo Xi, Dean Chou, Praveen V. Mummaneni, Shane Burch |
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DOI: http://doi.org/10.14245/ns.1938358.179 |
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| Editorial |
| Impact of Spinal Navigation on the Oblique Lumbar Interbody Fusion |
| Paul Park |
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DOI: http://doi.org/10.14245/ns.2040518.059 |
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| Original Article |
| Lower Extremity Motor Deficits Are Underappreciated in Patient-Reported Outcome Measures: Added Value of Objective Outcome Measures |
| Martin Nikolaus Stienen, Nicolai Maldaner, Marketa Sosnova, Holger Joswig, Marco Vincenzo Corniola, Luca Regli, Gerhard Hildebrandt, Karl Schaller, Oliver Pascal Gautschi |
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DOI: http://doi.org/10.14245/ns.1938368.184 |
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| Editorials |
| The Bull or the Horn – What Are Outcomes Data? |
| James Harrop |
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DOI: http://doi.org/10.14245/ns.2040106.053 |
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| Does the Rise of Objective Measure of Functional Impairment Mean the Fall of PROMs? |
| Satoshi Yamaguchi |
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DOI: http://doi.org/10.14245/ns.2040112.056 |
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| A New Possible Standard in Evaluating Lower Extremity Motor Weakness |
| Kern Singh |
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DOI: http://doi.org/10.14245/ns.2040072.036 |
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| Original Articles |
| A New Shielding Curtain for Protection of Intraoperative Radiation During Minimally Invasive Spine Surgery |
| Se Hoon Park, Myeong Jin Ko, Yong Sook Park, Jaehan Yun, Hongsik Byun, Seung Won Park |
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DOI: http://doi.org/10.14245/ns.1938282.141 |
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| Re-examining the Spectrum of Lumbosacral Transitional Dysmorphisms: Quantifying Joint Asymmetries and Evaluating the Anatomy of Screw Fixation Corridors |
| Niladri Kumar Mahato |
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DOI: http://doi.org/10.14245/ns.1938102.051 |
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| Oxford Cobbometer Versus Computer Assisted-Software for Measurement of Cobb Angle in Adolescent Idiopathic Scoliosis |
| Tarek Elfiky, Nirmal Patil, Mohamed Shawky, Ahmed Siam, Raafat Ragab, Yasser Allam |
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DOI: http://doi.org/10.14245/ns.1938260.130 |
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