Neurospine

Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.

The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Review Article

March 31, 2022

Hemostats in Spine Surgery: Literature Review and Expert Panel Recommendations

J.C. Le Huec, S. AlEissa, A.J. Bowey, B. Debono, A. El-Shawarbi, N. Fernández-Baillo, K.S. Han, A. Martin-Benlloch, R. Pflugmacher, P. Sabatier, et al.

Neurospine. 2022;19(1):1-12.

Bleeding in spine surgery is a common occurrence but when bleeding is uncontrolled the consequences can be severe due to the potential for spinal cord compression and damage to the...

Review Article

February 2, 2022

Glioma Immunotherapy: Advances and Challenges for Spinal Cord Gliomas

Clare Grady, Kaitlyn Melnick, Ken Porche, Farhad Dastmalchi, Daniel J. Hoh, Maryam Rahman, Ashley Ghiaseddin

Neurospine. 2022;19(1):13-29.

Spinal cord gliomas are rare entities that often have limited surgical options. Immunotherapy has shown promise in intracranial gliomas with some research suggesting benefit for spinal cord gliomas. A focused...

Original Article

January 30, 2022

Remnant Tumor Margin as Predictive Factor for Its Growth After Incomplete Resection of Cervical Dumbbell-Shaped Schwannomas

Kazuya Kitamura, Narihito Nagoshi, Osahiko Tsuji, Satoshi Suzuki, Satoshi Nori, Eijiro Okada, Mitsuru Yagi, Morio Matsumoto, Masaya Nakamura, Kota Watanabe

Neurospine. 2022;19(1):32-40.

Objective: The purpose of our study was to investigate the risk factors of remnant tumor growth after incomplete resection (IR) of cervical dumbbell-shaped schwannomas (DS). Methods: Twenty-one patients with IR of...

Original Article

January 30, 2022

Steroids in the Management of Preoperative Neurological Deficits in Metastatic Spine Disease: Results From the EPOSO Study

Anne L. Versteeg, Lior M. Elkaim, Arjun Sahgal, Laurence D. Rhines, Daniel M. Sciubba, James M. Schuster, Michael G. Fehlings, Aron Lazary, Michelle J. Clarke, Paul M. Arnold, et al.

Neurospine. 2022;19(1):43-50.

Objective: Patients presenting with neurological deficit secondary to metastatic epidural spinal cord compression (MESCC) are often treated with surgery in combination with high-dose corticosteroids. Despite steroids being commonly used, the...

Original Article

February 2, 2022

Frailty Status Is a More Robust Predictor Than Age of Spinal Tumor Surgery Outcomes: A NSQIP Analysis of 4,662 Patients

Syed Faraz Kazim, Alis J. Dicpinigaitis, Christian A. Bowers, Smit Shah, William T. Couldwell, Rachel Thommen, Daniel J. Alvarez-Crespo, Matthew Conlon, Omar H. Tarawneh, John Vellek, et al.

Neurospine. 2022;19(1):53-62.

Objective: The present study aimed to evaluate the effect of baseline frailty status (as measured by modified frailty index-5 [mFI-5]) versus age on postoperative outcomes of patients undergoing surgery for...

Original Article

February 3, 2022

Clinical Features, Treatments, and Prognosis of Intramedullary Spinal Cord Metastases From Lung Cancer: A Case Series and Systematic Review

Liang Wu, Li'ao Wang, Jun Yang, Wenqing Jia, Yulun Xu

Neurospine. 2022;19(1):65-76.

Objective: Intramedullary spinal cord metastasis from lung cancer (ISCM-LC) are increasing in prevalence. We aim to investigate its clinical features, treatments and prognosis. Methods: We reported 6 ISCM-LC cases and conducted...

Original Article

January 17, 2022

Recovery Potential of Spinal Meningioma Patients With Preoperative Loss of Walking Ability Following Surgery – A Retrospective Single-Center Study

Ville Vasankari, Roel Haeren, Mika Niemelä, Miikka Korja

Neurospine. 2022;19(1):77-83.

Objective: Spinal meningiomas are neurosurgical rarities that manifest with progressive paraor tetraparesis. The effect of timing of surgery on the recovery after the loss of walking ability is poorly known....

Original Article

March 31, 2022

Hardware Failure in Spinal Tumor Surgery: A Hallmark of Longer Survival?

Nikita Zaborovskii, Adam Schlauch, Dmitrii Ptashnikov, Dmitrii Mikaylov, Sergei Masevnin, Oleg Smekalenkov, John Shapton, Dimitriy Kondrashov

Neurospine. 2022;19(1):84-95.

Objective: Instrumentation failure in spine tumor surgery is a common reason for revision operation. Increases in patient survival demand a better understanding of the hardware longevity. The study objective was...

Original Article

March 31, 2022

Functional Outcome After Spinal Meningioma Surgery. A Nationwide Population-Based Study

Charles Champeaux-Depond, Nicolas Penet, Joconde Weller, Jean-Charles Le Huec, Vincent Jecko

Neurospine. 2022;19(1):96-107.

Objective: To describe and analysed the functional outcome (FO) after spinal meningioma (SM) surgery. Methods: We processed the système national des données de santé (SNDS) i.e. , the French national administrative...

Original Article

March 31, 2022

Intramedullary Spinal Cord Lesions: A Single-Center Experience

Vincent Jecko, Paul Roblot, Lorenzo Mongardi, Morgan Ollivier, Natalia Delgado Piccoli, Thomas Charleux, Thomas Wavasseur, Edouard Gimbert, Dominique Liguoro, Guillaume Chotard, et al.

Neurospine. 2022;19(1):108-117.

Objective: Spinal cord tumors constitute a small part of spinal surgery owing to their rarity. This retrospective study describes their current management. Methods: Forty-eight patients were treated for an intramedullary tumor...

Original Article

March 31, 2022

Long-term Neurologic Outcome After Spinal Ependymoma Resection With Multimodal Intraoperative Electrophysiological Recording: Cohort Study and Review of the Literature

Grégoire P. Chatain, Michael W. Kortz, Stephanie Serva, Keshari Shrestha, Patrick Hosokawa, Timothy H. Ung, Michael Finn

Neurospine. 2022;19(1):118-132.

Objective: To evaluate how multimodal intraoperative neuromonitoring (IONM) changes during spinal ependymoma (SE) resection correlate with long-term neuro-functional outcomes. Methods: A retrospective analysis of patients aged 18 years or older who...

Original Article

March 31, 2022

Prediction of Discharge Status and Readmissions after Resection of Intradural Spinal Tumors

Michael C. Jin, Allen L. Ho, Austin Y. Feng, Zachary A. Medress, Arjun V. Pendharkar, Paymon Rezaii, John K. Ratliff, Atman M. Desai

Neurospine. 2022;19(1):133-145.

Objective: Intradural spinal tumors are uncommon and while associations between clinical characteristics and surgical outcomes have been explored, there remains a paucity of literature unifying diverse predictors into an integrated...

Original Article

March 31, 2022

Mechanical Failure After Total En Bloc Spondylectomy and Salvage Surgery

Shin Won Kwon, Chun Kee Chung, Young Il Won, Woon Tak Yuh, Sung Bae Park, Seung Heon Yang, Chang Hyun Lee, John M. Rhee, Kyoung-Tae Kim, Chi Heon Kim

Neurospine. 2022;19(1):146-154.

Objective: Total en bloc spondylectomy (TES) is a curative surgical method for spinal tumors. After resecting the 3 spinal columns, reconstruction is of paramount importance. We present cases of mechanical...

Review Article

March 31, 2022

Pearls and Pitfalls of Oblique Lateral Interbody Fusion: A Comprehensive Narrative Review

Hyoungmin Kim, Bong-Soon Chang, Sam Yeol Chang

Neurospine. 2022;19(1):163-176.

Lumbar degenerative disease is a common problem in an aging society. Oblique lateral interbody fusion (OLIF) is a minimally invasive surgical (MIS) technique that utilizes a retroperitoneal antepsoas corridor to...

Review Article

January 29, 2022

Clinical Issues in Indication, Correction, and Outcomes of the Surgery for Neuromuscular Scoliosis: Narrative Review in Pedicle Screw Era

Hak Sun Kim, Ji Won Kwon, Kun-Bo Park

Neurospine. 2022;19(1):177-187.

Surgical treatment for neuromuscular scoliosis has evolved with pedicle screw instrumentation and the improvement of perioperative management. We aimed to review recent papers related to posterior surgical correction with a...

Original Article

January 2, 2022

Location Distribution of Fistulas and Surgical Strategies for Spinal Extradural Meningeal Cysts: A Retrospective Analysis of 30 Cases at a Single Center

Qiang Jian, Gang Song, Zhenlei Liu, Wanru Duan, Jian Guan, Fengzeng Jian, Zan Chen

Neurospine. 2022;19(1):188-201.

Objective: This study aimed to illustrate the features of fistula location distribution, surgical strategies, and outcomes in spinal epidural meningeal cysts (SEMCs). Methods: The authors searched and reviewed the medical records...

Original Article

February 2, 2022

Reconstruction of the Cervical Lateral Mass Using 3-Dimensional-Printed Prostheses

Qiang Jian, Zhenlei Liu, Wanru Duan, Jian Guan, Fengzeng Jian, Zan Chen

Neurospine. 2022;19(1):202-211.

Objective: This study aimed to investigate the outcome of using 3-dimensional (3D)-printed prostheses to reconstruct a cervical lateral mass to maintain cervical stability. Methods: We retrospectively analyzed data of 7 patients...

Original Article

February 2, 2022

Comparative Analysis of 3 Types of Minimally Invasive Posterior Cervical Foraminotomy for Foraminal Stenosis, Uniportal-, Biportal Endoscopy, and Microsurgery: Radiologic and Midterm Clinical Outcomes

Ji Yeon Kim, Hyun Jin Hong, Dong Chan Lee, Tae Hyun Kim, Jin Seob Hwang, Choon Keun Park

Neurospine. 2022;19(1):212-223.

Objective: The aim of this study was to compare the clinical and radiologic outcomes of 3 types of minimally invasive posterior cervical foraminotomy (PCF): uniportal endoscopic surgery, biportal endoscopic surgery,...

Original Article

March 31, 2022

Risk Factors for Poor Outcomes Following Minimally Invasive Discectomy: A Post Hoc Subgroup Analysis of 2-Year Follow-up Prospective Data

Zihao Chen, Lei He, Lijun Huang, Zhongyu Liu, Jianwen Dong, Bin Liu, Ruiqiang Chen, Liangming Zhang, Peigen Xie, Limin Rong

Neurospine. 2022;19(1):224-235.

Objective: A post hoc subgroup analysis of prospectively collected data from a randomized controlled trial was conducted to identify risk factors related to poor outcomes in patients who underwent minimally...

Original Article

March 31, 2022

The Last Touched Vertebra on Supine Radiographs Can Be the Optimal Lower Instrumented Vertebra in Adolescent Idiopathic Scoliosis Patients

Do-Hyoung Kim, Seung-Jae Hyun, Chang-Hyun Lee, Ki-Jeong Kim

Neurospine. 2022;19(1):236-243.

Objective: To determine whether the last touched vertebra (LTV) on supine radiographs is suitable for the lower instrumented vertebra (LIV) in adolescent idiopathic scoliosis (AIS) correction surgery. Methods: In total, 57...

Clinical Outcome and Influencing Factor for Repeat Lumbar Discectomy for Ipsilateral Recurrent Lumbar Disc Herniation (18,320 times) Yeon Sung Jung, Hyu Jin Choi, Young-Min Kwon Korean J Spine. 2012;9(1):1-5. Clinical Article March 31, 2012 Cited By 4 Full text PubReader PDF	Mid-term Clinical Outcomes of Stand-alone Posterior Interbody Fusion with Rectangular Cages: A 4-year-minimum Follow-up (18,308 times) Kyung Rae Cho, Sun-Ho Lee, Eun Sang Kim, Whan Eoh Korean J Spine. 2013;10(3):126-132. Clinical Article September 30, 2013 Cited By 2 Full text PubReader PDF
Unilateral Biportal Endoscopy for Decompression of Extraforaminal Stenosis at the Lumbosacral Junction: Surgical Techniques and Clinical Outcomes (5,027 times) Man-Kyu Park, Sang-Kyu Son, Weon Wook Park, Seung-Hyun Choi, Dae Young Jung, Dong Han Kim Neurospine. 2021;18(4):871-879. Original Article December 31, 2021 Full text PubReader ePub PDF Supplementary Material	Neurospine: Harmonious Launch of a New Intellectual Odyssey (2,584 times) Yoon Ha Neurospine. 2018;15(1):1-2. Editorial March 28, 2018 Cited By 1 Full text PubReader ePub PDF
Hemostats in Spine Surgery: Literature Review and Expert Panel Recommendations (1,541 times) J.C. Le Huec, S. AlEissa, A.J. Bowey, B. Debono, A. El-Shawarbi, N. Fernández-Baillo, K.S. Han, A. Martin-Benlloch, R. Pflugmacher, P. Sabatier, et al. Neurospine. 2022;19(1):1-12. Review Article March 31, 2022 Full text PubReader ePub PDF	Functional Outcomes of Subaxial Spine Injuries Managed With 2-Level Anterior Cervical Corpectomy and Fusion: A Prospective Study (1,432 times) Vaibhav Jain, Ankit Madan, Manoj Thakur, Amit Thakur Neurospine. 2018;15(4):368-375. Original Article October 15, 2018 Cited By 7 Full text PubReader ePub PDF
Superior and Middle Cluneal Nerve Entrapment as a Cause of Low Back Pain (1,300 times) Toyohiko Isu, Kyongsong Kim, Daijiro Morimoto, Naotaka Iwamoto Neurospine. 2018;15(1):25-32. Review Article March 28, 2018 Cited By 31 Full text PubReader ePub PDF	Proximal Junctional Kyphosis and Proximal Junctional Failure Following Adult Spinal Deformity Surgery (990 times) Seung-Jae Hyun, Byoung Hun Lee, Jong-Hwa Park, Ki-Jeong Kim, Tae-Ahn Jahng, Hyun-Jib Kim Korean J Spine. 2017;14(4):126-132. Review Article December 31, 2017 Cited By 58 Full text PubReader ePub PDF
Deep Learning in Medical Imaging (977 times) Mingyu Kim, Jihye Yun, Yongwon Cho, Keewon Shin, Ryoungwoo Jang, Hyun-jin Bae, Namkug Kim Neurospine. 2019;16(4):657-668.Correction in: Neurospine 2020;17(2):471 Review Article December 31, 2019 Cited By 53 Full text PubReader ePub PDF	The Last Touched Vertebra on Supine Radiographs Can Be the Optimal Lower Instrumented Vertebra in Adolescent Idiopathic Scoliosis Patients (968 times) Do-Hyoung Kim, Seung-Jae Hyun, Chang-Hyun Lee, Ki-Jeong Kim Neurospine. 2022;19(1):236-243. Original Article March 31, 2022 Full text PubReader ePub PDF
Dynamic Cord Compression Causing Cervical Myelopathy (952 times) Andrei Fernandes Joaquim, Griffin R. Baum, Lee A. Tan, K. Daniel Riew Neurospine. 2019;16(3):448-453. Review Article July 24, 2019 Cited By 9 Full text PubReader ePub PDF	Pearls and Pitfalls of Oblique Lateral Interbody Fusion: A Comprehensive Narrative Review (933 times) Hyoungmin Kim, Bong-Soon Chang, Sam Yeol Chang Neurospine. 2022;19(1):163-176. Review Article March 31, 2022 Full text PubReader ePub PDF
Glioma Immunotherapy: Advances and Challenges for Spinal Cord Gliomas (924 times) Clare Grady, Kaitlyn Melnick, Ken Porche, Farhad Dastmalchi, Daniel J. Hoh, Maryam Rahman, Ashley Ghiaseddin Neurospine. 2022;19(1):13-29. Review Article February 2, 2022 Cited By 2 Full text PubReader ePub PDF	Symptomatic Epidural Gas-containing Cyst from Intervertebral Vacuum Phenomenon (906 times) Sung Min Yun, Bumn Suk Suh, Jin Su Park Korean J Spine. 2012;9(4):365-368. Case Report December 31, 2012 Cited By 11 Full text PubReader PDF
Comparative Analysis of 3 Types of Minimally Invasive Posterior Cervical Foraminotomy for Foraminal Stenosis, Uniportal-, Biportal Endoscopy, and Microsurgery: Radiologic and Midterm Clinical Outcomes (899 times) Ji Yeon Kim, Hyun Jin Hong, Dong Chan Lee, Tae Hyun Kim, Jin Seob Hwang, Choon Keun Park Neurospine. 2022;19(1):212-223. Original Article February 2, 2022 Full text PubReader ePub PDF	Steroids in the Management of Preoperative Neurological Deficits in Metastatic Spine Disease: Results From the EPOSO Study (878 times) Anne L. Versteeg, Lior M. Elkaim, Arjun Sahgal, Laurence D. Rhines, Daniel M. Sciubba, James M. Schuster, Michael G. Fehlings, Aron Lazary, Michelle J. Clarke, Paul M. Arnold, et al. Neurospine. 2022;19(1):43-50. Original Article January 30, 2022 Cited By 1 Full text PubReader ePub PDF
Risk Factors for Poor Outcomes Following Minimally Invasive Discectomy: A Post Hoc Subgroup Analysis of 2-Year Follow-up Prospective Data (872 times) Zihao Chen, Lei He, Lijun Huang, Zhongyu Liu, Jianwen Dong, Bin Liu, Ruiqiang Chen, Liangming Zhang, Peigen Xie, Limin Rong Neurospine. 2022;19(1):224-235. Original Article March 31, 2022 Full text PubReader ePub PDF	Prediction of Discharge Status and Readmissions after Resection of Intradural Spinal Tumors (868 times) Michael C. Jin, Allen L. Ho, Austin Y. Feng, Zachary A. Medress, Arjun V. Pendharkar, Paymon Rezaii, John K. Ratliff, Atman M. Desai Neurospine. 2022;19(1):133-145. Original Article March 31, 2022 Full text PubReader ePub PDF Supplementary Material
Biomaterials in Spinal Implants: A Review (864 times) Andrew Warburton, Steven J. Girdler, Christopher M. Mikhail, Amy Ahn, Samuel K. Cho Neurospine. 2020;17(1):101-110. Review Article November 4, 2019 Cited By 31 Full text PubReader ePub PDF	Sacral Nerves Reconstruction After Surgical Resection of a Large Sacral Chordoma Restores the Urinary and Sexual Function and the Anal Continence (863 times) Luigi Valentino Berra, Daniele Armocida, Mauro Palmieri, Valerio Di Norcia, Luca D’Angelo, Massimo Mongardini, Massimo Vigliotta, Edoardo Maccari, Antonio Santoro Neurospine. 2022;19(1):155-162. Technical Note January 30, 2022 Full text PubReader ePub PDF
Clinical Features, Treatments, and Prognosis of Intramedullary Spinal Cord Metastases From Lung Cancer: A Case Series and Systematic Review (854 times) Liang Wu, Li'ao Wang, Jun Yang, Wenqing Jia, Yulun Xu Neurospine. 2022;19(1):65-76. Original Article February 3, 2022 Full text PubReader ePub PDF	Ossification of the Posterior Longitudinal Ligament: Surgical Approaches and Associated Complications (851 times) Jeffery Head, George Rymarczuk, Geoffrey Stricsek, Lohit Velagapudi, Christopher Maulucci, Christian Hoelscher, James Harrop Neurospine. 2019;16(3):517-529. Review Article September 30, 2019 Cited By 25 Full text PubReader ePub PDF
Outcome Measures and Variables Affecting Prognosis of Cervical Spondylotic Myelopathy: WFNS Spine Committee Recommendations (850 times) Mehmet Zileli, Shradha Maheshwari, Shashank Sharad Kale, Kanwaljeet Garg, Sajesh K. Menon, Jutty Parthiban Neurospine. 2019;16(3):435-447. Review Article September 30, 2019 Cited By 8 Full text PubReader ePub PDF	Review of Radiological Parameters, Imaging Characteristics, and Their Effect on Optimal Treatment Approaches and Surgical Outcomes for Cervical Ossification of the Posterior Longitudinal Ligament (845 times) Nobuyuki Shimokawa, Hidetoshi Sato, Hiroaki Matsumoto, Toshihiro Takami Neurospine. 2019;16(3):506-516. Review Article September 30, 2019 Cited By 9 Full text PubReader ePub PDF
Mechanical Failure After Total En Bloc Spondylectomy and Salvage Surgery (831 times) Shin Won Kwon, Chun Kee Chung, Young Il Won, Woon Tak Yuh, Sung Bae Park, Seung Heon Yang, Chang Hyun Lee, John M. Rhee, Kyoung-Tae Kim, Chi Heon Kim Neurospine. 2022;19(1):146-154. Original Article March 31, 2022 Full text PubReader ePub PDF	Technique of Biportal Endoscopic Transforaminal Lumbar Interbody Fusion (795 times) Dong Hwa Heo, Young Ho Hong, Dong Chan Lee, Hun Jae Chung, Choon Keun Park Neurospine. 2020;17(Suppl 1):S129-S137. Review and Technical Note July 31, 2020 Cited By 16 Full text PubReader ePub PDF Supplementary Material
Scientific Achievements of Our Era: “Making the Lame Walk” (788 times) Martin N. Stienen, Yoon Ha Neurospine. 2022;19(1):246-248. Editorial March 31, 2022 Full text PubReader ePub PDF	Remnant Tumor Margin as Predictive Factor for Its Growth After Incomplete Resection of Cervical Dumbbell-Shaped Schwannomas (787 times) Kazuya Kitamura, Narihito Nagoshi, Osahiko Tsuji, Satoshi Suzuki, Satoshi Nori, Eijiro Okada, Mitsuru Yagi, Morio Matsumoto, Masaya Nakamura, Kota Watanabe Neurospine. 2022;19(1):32-40. Original Article January 30, 2022 Cited By 1 Full text PubReader ePub PDF
The Impact of Spinal Cord Neuromodulation on Restoration of Walking Ability After Spinal Cord Injury (784 times) Michael G. Fehlings, Alexander A. Velumian Neurospine. 2022;19(1):244-245. Editorial March 31, 2022 Full text PubReader ePub PDF	Regional Anesthesia for Lumbar Spine Surgery: Can It Be a Standard in the Future? (783 times) Jae-Koo Lee, Jong Hwa Park, Seung-Jae Hyun, Daniel Hodel, Oliver N. Hausmann Neurospine. 2021;18(4):733-740. Review Article December 31, 2021 Cited By 3 Full text PubReader ePub PDF